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The map label for this gene is ho1 [H]

Identifier: 126697124

GI number: 126697124

Start: 1507241

End: 1507951

Strand: Reverse

Name: ho1 [H]

Synonym: P9301_17861

Alternate gene names: 126697124

Gene position: 1507951-1507241 (Counterclockwise)

Preceding gene: 126697125

Following gene: 126697123

Centisome position: 91.84

GC content: 31.36

Gene sequence:

>711_bases
ATGGCAGTTGCTCTTGCAGGACAATTAAGAGAAGGGACAAAAAAATCCCATACTATGGCAGAAAATACTGGCTTTGTGGC
TTGTTTTTTAAAAGGAGTTGTTGAAAAAAAATCTTATAGAAAATTAATTAGCGATTTATATTTTGTTTATGAAGCTATGG
AAGAAGAAATTGAAAGACTGGTCAATGAGGAACATCCCGTAATAAAACCTATAGGTTTTAAATCATTATTCAGGAAAGAA
ACTCTTGTAAATGATCTTAAATTTTATTTTGGTGAAAACTGGAAGAATGAAATTAATATTTCTCACTCAGCAAAAGAATA
TGTTGAAAGAATCCGAGAGGTCGCAAAAAATTCACCAGAGCTCTTAGTTGGTCATCACTATACTCGCTATATAGGAGATT
TATCTGGGGGGCAAATCTTGAAAAGGATCGCTAAAAAAGCATTAAATTTGCAGGGAAATGATGGTTTAAATTTTTATGAG
TTTGAATTAATTGCTGATGAAAAGAAATTCAAGGAAGAATATTCCCTTACTTTGAATCAACTTCCAATAAATCAAAAGAC
GGCTGATCAAATTATTGATGAAGCTAATCAAGCTTTTACTTACAATATGAAAATGTTTAAGGAGCTTGAAGGTAACTTGA
TTGCTGTTTTAGGCAAAATTGTATTTAATTACATTACAAAAAAAGTTAGGAAAGGAAGTACCGAGACCTAA

Upstream 100 bases:

>100_bases
TTATAAGCTATTCTCTACAACATCCGCTGGTAACAAAAATTAGCTGTTTTATGTATTTTCCTTGTAGATTAAATACACTT
ACAAAAATAATTCAAAATAT

Downstream 100 bases:

>100_bases
AATTTATGTTTGATTCATTAGTTGATTTCCTTAAAACCAATATTGATGAATTAAATGGACATGAAGTACAAATATCTGGT
GAATTTAAAGAACATCATAA

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYEAMEEEIERLVNEEHPVIKPIGFKSLFRKE
TLVNDLKFYFGENWKNEINISHSAKEYVERIREVAKNSPELLVGHHYTRYIGDLSGGQILKRIAKKALNLQGNDGLNFYE
FELIADEKKFKEEYSLTLNQLPINQKTADQIIDEANQAFTYNMKMFKELEGNLIAVLGKIVFNYITKKVRKGSTET

Sequences:

>Translated_236_residues
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYEAMEEEIERLVNEEHPVIKPIGFKSLFRKE
TLVNDLKFYFGENWKNEINISHSAKEYVERIREVAKNSPELLVGHHYTRYIGDLSGGQILKRIAKKALNLQGNDGLNFYE
FELIADEKKFKEEYSLTLNQLPINQKTADQIIDEANQAFTYNMKMFKELEGNLIAVLGKIVFNYITKKVRKGSTET
>Mature_235_residues
AVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYEAMEEEIERLVNEEHPVIKPIGFKSLFRKET
LVNDLKFYFGENWKNEINISHSAKEYVERIREVAKNSPELLVGHHYTRYIGDLSGGQILKRIAKKALNLQGNDGLNFYEF
ELIADEKKFKEEYSLTLNQLPINQKTADQIIDEANQAFTYNMKMFKELEGNLIAVLGKIVFNYITKKVRKGSTET

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=208, Percent_Identity=47.5961538461538, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI187761309, Length=208, Percent_Identity=47.5961538461538, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI187761307, Length=208, Percent_Identity=47.5961538461538, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI8051608, Length=208, Percent_Identity=47.5961538461538, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI4504437, Length=212, Percent_Identity=43.8679245283019, Blast_Score=181, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 27189; Mature: 27057

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYEAMEEEIERL
CCEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNEEHPVIKPIGFKSLFRKETLVNDLKFYFGENWKNEINISHSAKEYVERIREVAKNSPE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
LLVGHHYTRYIGDLSGGQILKRIAKKALNLQGNDGLNFYEFELIADEKKFKEEYSLTLNQ
EEECCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHC
LPINQKTADQIIDEANQAFTYNMKMFKELEGNLIAVLGKIVFNYITKKVRKGSTET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYEAMEEEIERL
CEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNEEHPVIKPIGFKSLFRKETLVNDLKFYFGENWKNEINISHSAKEYVERIREVAKNSPE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
LLVGHHYTRYIGDLSGGQILKRIAKKALNLQGNDGLNFYEFELIADEKKFKEEYSLTLNQ
EEECCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHC
LPINQKTADQIIDEANQAFTYNMKMFKELEGNLIAVLGKIVFNYITKKVRKGSTET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]