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The map label for this gene is era [H]

Identifier: 126696804

GI number: 126696804

Start: 1234169

End: 1235080

Strand: Reverse

Name: era [H]

Synonym: P9301_14661

Alternate gene names: 126696804

Gene position: 1235080-1234169 (Counterclockwise)

Preceding gene: 126696806

Following gene: 126696803

Centisome position: 75.22

GC content: 31.47

Gene sequence:

>912_bases
TTGGCCAATTATAGATCTGGGTTTGTAACTTTACTAGGAAGGCCAAATGTTGGTAAATCTACTTTAATAAATAAATTGAT
TGGAGAAAAAATAACAATTACTTCTCCAATAGCGCAAACTACTAGAAATAAATTAAAAGGAATACTTACTACAGACAATG
GACAAATAATTTTTGTTGATACCCCAGGTGTTCATAAACCTCATCATCGACTTGGTGAGATATTAGTAAAAAACGCAAAA
TCTGCAATTAATGGAGTTGATATGGTGATTTTTGTAATTGATTCAAGTGAAGAACCTGGTAGAGGTGATGAATATATTTT
GAACTTTCTAATCTCAAATAAAACTGAGTTTATTGTGGCATTAAATAAGTGGGATTTGGTTAATAAAGAATTTAGGAATT
TAAGATTAGATCAATATAGAAGATTTTTTGGAATTAATAGAAACTTTCAAATTGTAAGTGCTTCTCAAGGAGAGGGATGT
TCTGAACTAGTCGATATGGCACTTAATTTTCTTCCAGAGGGACCAAAACTTTATGGCGAAGAGACGATTTGCGACCAACC
ATTAGATAACTTATTATCTGATTTAGTGAGAGAGCAGGTATTAAAAAATACAAGAGAAGAGGTACCTCATAGTGTGGCAG
TAAAGATAGAAAAGATGGAGGAAATGAAAAGAAAAAATGGCAAAGTTTTTACAGCTATTTTGGCTACTATTATTGTTGAA
AGATCAACTCAAAAAGGCATTCTTATTGGAAAGAAAGGTTCAATGTTAAAAATGATTGGTCAGTCAGCAAGAGCAAATAT
GTCAAAATTAATTGATTGTCCAGTTCACTTAGAGTTGTTTGTGAAAGTTATTCCAAATTGGAGAAAAAAAGAATCAAGGT
TAATTGAGTTTGGTTATGAGGAAGATTTCTAG

Upstream 100 bases:

>100_bases
GCGGATATGTTTATTGCTTGCGTGAACGAAGCTTCTTTAAAATTTATGGTTTTTTTTTCCATTTTTGATCAGAATTTTAT
TATTGATGCATTAAAAGTCT

Downstream 100 bases:

>100_bases
ATGAGTGGTTTTAATTTTGATGTAATTACATTATTCCCTAAAGCTTTTGAATTGATAAATAATTTAGGGGTCATAACAAA
AGCTCTAGATAAGAATTTGA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MANYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTDNGQIIFVDTPGVHKPHHRLGEILVKNAK
SAINGVDMVIFVIDSSEEPGRGDEYILNFLISNKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGINRNFQIVSASQGEGC
SELVDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKMEEMKRKNGKVFTAILATIIVE
RSTQKGILIGKKGSMLKMIGQSARANMSKLIDCPVHLELFVKVIPNWRKKESRLIEFGYEEDF

Sequences:

>Translated_303_residues
MANYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTDNGQIIFVDTPGVHKPHHRLGEILVKNAK
SAINGVDMVIFVIDSSEEPGRGDEYILNFLISNKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGINRNFQIVSASQGEGC
SELVDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKMEEMKRKNGKVFTAILATIIVE
RSTQKGILIGKKGSMLKMIGQSARANMSKLIDCPVHLELFVKVIPNWRKKESRLIEFGYEEDF
>Mature_302_residues
ANYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTDNGQIIFVDTPGVHKPHHRLGEILVKNAKS
AINGVDMVIFVIDSSEEPGRGDEYILNFLISNKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGINRNFQIVSASQGEGCS
ELVDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKMEEMKRKNGKVFTAILATIIVER
STQKGILIGKKGSMLKMIGQSARANMSKLIDCPVHLELFVKVIPNWRKKESRLIEFGYEEDF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=38.2059800664452, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=29.1925465838509, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=161, Percent_Identity=31.055900621118, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34247; Mature: 34116

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTDNGQIIFVD
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHCEEEEECCCEEEEEE
TPGVHKPHHRLGEILVKNAKSAINGVDMVIFVIDSSEEPGRGDEYILNFLISNKTEFIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEE
LNKWDLVNKEFRNLRLDQYRRFFGINRNFQIVSASQGEGCSELVDMALNFLPEGPKLYGE
ECCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKMEEMKRKNGKVFTAILATIIVE
CHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RSTQKGILIGKKGSMLKMIGQSARANMSKLIDCPVHLELFVKVIPNWRKKESRLIEFGYE
CCCCCCEEEECCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHEECCCC
EDF
CCC
>Mature Secondary Structure 
ANYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTDNGQIIFVD
CCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHCEEEEECCCEEEEEE
TPGVHKPHHRLGEILVKNAKSAINGVDMVIFVIDSSEEPGRGDEYILNFLISNKTEFIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEE
LNKWDLVNKEFRNLRLDQYRRFFGINRNFQIVSASQGEGCSELVDMALNFLPEGPKLYGE
ECCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKMEEMKRKNGKVFTAILATIIVE
CHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RSTQKGILIGKKGSMLKMIGQSARANMSKLIDCPVHLELFVKVIPNWRKKESRLIEFGYE
CCCCCCEEEECCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHEECCCC
EDF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA