Click here to switch to the map view.

The map label for this gene is pheS [H]

Identifier: 126696793

GI number: 126696793

Start: 1226716

End: 1227723

Strand: Reverse

Name: pheS [H]

Synonym: P9301_14551

Alternate gene names: 126696793

Gene position: 1227723-1226716 (Counterclockwise)

Preceding gene: 126696795

Following gene: 126696792

Centisome position: 74.78

GC content: 33.53

Gene sequence:

>1008_bases
GTGAGTCAAATTGAATCATTAAGTCAAATTGAGGAAAAACTAAATAATCTTTCTCTAACAGCAAAAAATAATATAGATAA
TTCTAATACTCATGAAGAACTTGATCAATTGAGAGTTTCATTGCTAGGGAAAAAAGGTGATTTATCAATTATCTTGAAAA
CAATGGGTCAACTATCTGCTACTGATAGACCAATTGTTGGCCAGAAGGCAAATTTAATAAAGATAAATTTGCAAGAACTA
ATAACTGAAAGAAAAAGTCAACTGAATAGTGAAGCCTTAGATAAGAAGATTAAAACAGAAAAAATTGATGTAACTATCCC
TTCAATTGGAACTCCCTCTGGAAATAAACATCCTTTAATTTCAACCCAAGATGAAATAATTGATATTTTTTGTGGTTTAG
GTTACTCAGTTGAAAGTGGCCCTGAAATAGAGACTGATTTTTATAATTTTGAGTCTCTCAATATACCCAAAAATCATCCC
GCAAGAGATATGCAGGATACTTTCTACTTAGATGAAAATCGACTTTTGAGGACCCATACTTCTCCTGTTCAGATAAGGTA
TTTAGAGAAAAATCCTCCTCCAGTAAGAATAATTGCCCCTGGAAGGGTTTATAGGAGAGATGCTGTAGATGCTACACATT
CCCCTGTATTTAATCAGGTTGAGGTTTTATGTATCGATCAAGATATCAATTTTAGTCATTTAAGAGGAACAGTTCTTACA
TTTTTAAAGTCCTTTTTTGGAGATATTCCTGTGAGATTTAGAGCTAGTTATTTCCCCTTTACTGAACCTTCAGCAGAAGT
AGACGTCCAGTGGAAAGGTAAATGGCTGGAAGTAATGGGCTGCGGAATGGTAGATCCAAAGGTCTTAGAAAAATTAGGAA
TAGATTCTGAGAAATGGACAGGATTCGCTGCAGGATTAGGAGTTGAAAGATTTTGTATGGTAAGACATCAGATTGATGAC
ATCAGAAAATTTTATACAAATGATATTAGATTCTTAGAACAGTTCTAA

Upstream 100 bases:

>100_bases
TCATTACTAATTAATATATTTAACGGTTTCATTAATTAATACATTTTATTTATGGACGATATTTAAGTAAGATAAAACAA
TACTTCTTTTTACTATATCA

Downstream 100 bases:

>100_bases
TAGGATTTAATTCTTAAATTAGGATTGTCCAACAAATTAGTTTAAGATAGTCCTAGTTTTAATTTTTTGATTGGTACGTA
AAGCAGGGCTAATAGTTAAT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSQIESLSQIEEKLNNLSLTAKNNIDNSNTHEELDQLRVSLLGKKGDLSIILKTMGQLSATDRPIVGQKANLIKINLQEL
ITERKSQLNSEALDKKIKTEKIDVTIPSIGTPSGNKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHP
ARDMQDTFYLDENRLLRTHTSPVQIRYLEKNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFSHLRGTVLT
FLKSFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFCMVRHQIDD
IRKFYTNDIRFLEQF

Sequences:

>Translated_335_residues
MSQIESLSQIEEKLNNLSLTAKNNIDNSNTHEELDQLRVSLLGKKGDLSIILKTMGQLSATDRPIVGQKANLIKINLQEL
ITERKSQLNSEALDKKIKTEKIDVTIPSIGTPSGNKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHP
ARDMQDTFYLDENRLLRTHTSPVQIRYLEKNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFSHLRGTVLT
FLKSFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFCMVRHQIDD
IRKFYTNDIRFLEQF
>Mature_334_residues
SQIESLSQIEEKLNNLSLTAKNNIDNSNTHEELDQLRVSLLGKKGDLSIILKTMGQLSATDRPIVGQKANLIKINLQELI
TERKSQLNSEALDKKIKTEKIDVTIPSIGTPSGNKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHPA
RDMQDTFYLDENRLLRTHTSPVQIRYLEKNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFSHLRGTVLTF
LKSFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFCMVRHQIDDI
RKFYTNDIRFLEQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=229, Percent_Identity=33.1877729257642, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI4758340, Length=264, Percent_Identity=31.8181818181818, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1788007, Length=324, Percent_Identity=50, Blast_Score=333, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI32566635, Length=264, Percent_Identity=34.0909090909091, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563657, Length=264, Percent_Identity=29.5454545454545, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17508957, Length=264, Percent_Identity=29.5454545454545, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321087, Length=371, Percent_Identity=28.8409703504043, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6325304, Length=88, Percent_Identity=42.0454545454545, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17137424, Length=277, Percent_Identity=29.2418772563177, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18858079, Length=265, Percent_Identity=29.4339622641509, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38131; Mature: 38000

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIESLSQIEEKLNNLSLTAKNNIDNSNTHEELDQLRVSLLGKKGDLSIILKTMGQLSA
CCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
TDRPIVGQKANLIKINLQELITERKSQLNSEALDKKIKTEKIDVTIPSIGTPSGNKHPLI
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
STQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHPARDMQDTFYLDENRLLRTHT
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHEEECCCCEEEECC
SPVQIRYLEKNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFSHLRGTVLT
CCEEEEEEECCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
FLKSFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWT
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHCCCCHHCC
GFAAGLGVERFCMVRHQIDDIRKFYTNDIRFLEQF
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQIESLSQIEEKLNNLSLTAKNNIDNSNTHEELDQLRVSLLGKKGDLSIILKTMGQLSA
CHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
TDRPIVGQKANLIKINLQELITERKSQLNSEALDKKIKTEKIDVTIPSIGTPSGNKHPLI
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
STQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHPARDMQDTFYLDENRLLRTHT
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHEEECCCCEEEECC
SPVQIRYLEKNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFSHLRGTVLT
CCEEEEEEECCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
FLKSFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWT
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHCCCCHHCC
GFAAGLGVERFCMVRHQIDDIRKFYTNDIRFLEQF
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA