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The map label for this gene is engD [H]

Identifier: 126696665

GI number: 126696665

Start: 1106265

End: 1107356

Strand: Reverse

Name: engD [H]

Synonym: P9301_13271

Alternate gene names: 126696665

Gene position: 1107356-1106265 (Counterclockwise)

Preceding gene: 126696670

Following gene: 126696662

Centisome position: 67.44

GC content: 32.88

Gene sequence:

>1092_bases
ATGTTAAAAGCAGGTATTATTGGATTACCAAATGTTGGAAAATCAACCCTATTTAATGCACTTGTAGAAAATGCTAAGGC
CCAAGCGGCTAATTTTCCCTTTTGTACTATAGAACCTAATAAAGGCATAGTTTCAGTCCCGGATCAAAGGTTGCAAGAGT
TAGGTAATTTAAGTTGTAGCCAAAATATTATCCCAACAAAAATTGAATTTGTAGATATCGCAGGACTAGTAAAAGGAGCT
AGTAAAGGCGAAGGCTTGGGAAATAAATTTTTATCAAATATTAGGGAGGTTGATGCAATAGTTCATGTTGTAAGGTGCTT
TGAAGATAGTGATGTAATTCATGTTTCTGGAAAGGTAGATCCCCTGGATGACATTGAGATAATTAATCTGGAATTGAATT
TAGCTGATTTATCTCAACTCCAAAAAAGAAGAGAAAGAATTAAAAAACAGGTTAGAACTAGTAAAGAGGCAGCTAAAGAA
GATACCTTACTAGAAAAAATTGAAGAAGAGCTAGAGAAAGGCCTTTCAGTTAGATCAATATCTTTGAATGAAGAAGAAAA
TTTAATAATTAAGCAATTAGGCTTCCTTACTGCTAAACCAATTATTTACGCAACTAATTTGAATGAAAATGATTTAGCTG
AAGGTAATGATTTTTCATCAACAGTTCAGAGTTTTGCAAGCAATGAAAATACAGAATGTATAAAAATATCAGCGCAAGTC
GAATCTGAATTAATAGAGTTAGAACCAGAAGATAAAAAAGACTACCTTATCGGCTTAGGAGTAGAAGAAGGGGGATTAAG
TTCATTAATTAGATCAACATATAAATTATTGGGATTAAAAACTTATTTCACTACCGGTGAAAAGGAGACAAAAGCTTGGA
CAATAAAAGATGGGATGACTGCGCCACAGGCAGCAGGAGTAATTCATACTGATTTTGAAAAAGGATTTATAAGAGCTCAG
ACTATTTCCTATCAAAATTTAATTGATTCAGGTTCAATTGCCAATGCAAAAACTAAAGGTCTTTTAAGAAGTGAAGGTAA
GGAATATATTGTTAACGAAGGTGATGTAATGGAGTTCTTATTTAACGTTTAG

Upstream 100 bases:

>100_bases
ATAATCAAAACGATTATAATTAACTTATCCAAGATTGGTTAAGTAAATACTATATTACTAGAAGATGTTTTCTTGATAAT
TTTCCCATAAGTTTTTTCAA

Downstream 100 bases:

>100_bases
TAAGTCTCTTAAGGCTTACTATTTTGCTTTTTGAATTTAAATTCAAAAAATGAAATTAATAAAATTAAGATACATCCTAA
GCAACTTCCTATTAACCCAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSCSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSTVQSFASNENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSCSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSTVQSFASNENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV
>Mature_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSCSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSTVQSFASNENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=40.7608695652174, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI58761502, Length=184, Percent_Identity=36.4130434782609, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=54.8209366391185, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=43.3242506811989, Blast_Score=284, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=40.2173913043478, Blast_Score=246, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=35.1851851851852, Blast_Score=215, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=172, Percent_Identity=38.3720930232558, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24640873, Length=376, Percent_Identity=40.1595744680851, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640877, Length=376, Percent_Identity=40.1595744680851, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640875, Length=376, Percent_Identity=40.1595744680851, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=37.4251497005988, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24585318, Length=141, Percent_Identity=35.4609929078014, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39927; Mature: 39927

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSCS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDTLLEKIEEELEKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLNEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSTVQSFASNENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEHH
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSCS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDTLLEKIEEELEKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLNEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSTVQSFASNENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEHH
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]