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The map label for this gene is sasA

Identifier: 126696522

GI number: 126696522

Start: 996740

End: 997858

Strand: Reverse

Name: sasA

Synonym: P9301_11841

Alternate gene names: 126696522

Gene position: 997858-996740 (Counterclockwise)

Preceding gene: 126696525

Following gene: 126696520

Centisome position: 60.78

GC content: 34.23

Gene sequence:

>1119_bases
TTGAATGATAAAAAAGAGTTAAAATTAATACTTGTGGCAGCTAGAAATCAACTTTCTAGTAATGACATTAAGTCCTTAAT
AGCTTATCTAGAATCAGATGATTGTGAATTTGAGATATCTCTCCAGATTTCTGAGCCTACAGAGCAACCAGAATTACTCG
AATTACATAGATTAGTAGCTATTCCTGCCCTTATAAAAGTTTCTCCAGCTCCAAAACAAATATTTGCTGGAAGTAATATT
TTTTCTCAGTTGCAAAAGTGGTTGCCAAGATGGACACAGGAAGGCTTAACAAAAAATCTTGGGATTAATTTGCAACCATC
TAAAATTGATTCAATAAGAACTCAAAAAGAATTTCTATTAGAAGATGAACTTCTCGTTTTAAGACAAGAAAATGAGACTT
TAACAAAAAGAATTGAGTCTCAGGAGAGATTGTTAAGAATGGTCGCGCATGAATTAAGGACACCTTTAACGGCTGCTACT
TTGGCTGTTCAAAGTCAAAAACTAGGACAAATAGATATTTCAAAATTGCAAGAGGTAATAAAAAGACGTCTAGAAGAAAT
TGAACTCTTATCTCAGGATCTATTAGAGGTTGGAACAACCAAATGGGAAGCGTTATTTAATCCTCAGAAAATTGATTTAG
GTAATATTAGTGCTGAAGTAATACTCGAATTAGAAAAATTCTGGAGATTAAGGAATATTGAAATTGATACTGATATTCCA
TCTGATCTGCCAAGTGTATTTGCAGATCAAAGAAGAATGAGGCAAGTATTTTTAAATTTAATTGAAAATGCTATTAAATT
TTCTAGAGATTCTGGATCTATAAAAATCACGATGATTCACAAGACAAATCAATGGGTAGAAATAACAATTTGTGACAAAG
GTGCAGGTATTCCTTTGAGCGAACAAAAAAGAATTTTTCTTGATAGGGTAAGACTCCCGCAGACTTCTGAAGGAACTTCA
GGATTTGGCATAGGTTTATCAGTATGCAGGAGAATAGTACAAGTCCATGGAGGAAGAATATGGGTGGTATCTGAAGTTGG
CGTAGGTTCGTGCTTTCATTTCACAGTTCCTGTGTGGCAAGGACAAAACAAAGAGCAACAATACTTGACGAAAGGCTAG

Upstream 100 bases:

>100_bases
ATAAGTCCTATTTATTTAATAGCTTATCTGTAAAATAAAAATAAATATCTTAAGGTGTTTATAAGGATTAACAGCTTTTC
AACACTTCAGAGGAAATCAT

Downstream 100 bases:

>100_bases
CCTTACTCTTAGTTTTTAATAAGCTGTTATACTAATTTCCTGGCCCCATCGTCTAGAGGCCTAGGACACCTCCCTTTCAC
GGAGGCGACAGGGGTTCGAA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQYLTKG

Sequences:

>Translated_372_residues
MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQYLTKG
>Mature_372_residues
MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQYLTKG

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.9256198347107, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.3913043478261, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=30.2040816326531, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=30.4721030042918, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=25.3275109170306, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=237, Percent_Identity=28.6919831223629, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=24.6753246753247, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SASA_PROM0 (A3PDI2)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091408.1
- ProteinModelPortal:   A3PDI2
- STRING:   A3PDI2
- GeneID:   4911836
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_11841
- eggNOG:   COG0642
- HOGENOM:   HBG284956
- OMA:   VEITICD
- ProtClustDB:   PRK09303
- BioCyc:   PMAR167546:P9301ORF_1205-MONOMER
- GO:   GO:0016020
- HAMAP:   MF_01837
- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.30.565.10
- Gene3D:   G3DSA:3.40.30.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim; SSF52833 Thiordxn-like_fd

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42439; Mature: 42439

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVA
CCCHHHEEEEEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDISKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQQYLTKG
CCCCHHHHCCCC
>Mature Secondary Structure
MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVA
CCCHHHEEEEEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDISKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQQYLTKG
CCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA