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The map label for this gene is cumB [H]

Identifier: 126696279

GI number: 126696279

Start: 809707

End: 810222

Strand: Reverse

Name: cumB [H]

Synonym: P9301_09411

Alternate gene names: 126696279

Gene position: 810222-809707 (Counterclockwise)

Preceding gene: 126696282

Following gene: 126696277

Centisome position: 49.35

GC content: 32.56

Gene sequence:

>516_bases
ATGAGGTATATTTTTGAAAATGTAAATAGTAATTATGATGAACAGAAAGGAACAAATACTCTAAAATACACCAAATGGAT
GAGTTCTATTTTAAGAAGATCAGAAGAAATTGGAAAAGTTGAGTTACCAATCTGTTCAATAATTTTAGATGAGAGAGGAA
GATGTATTGGAAGAGGGGTTAATAGGAGAAATATAAATAATGATCCATTGGGTCATGCTGAAATTATGGCACTAAGGCAG
GCATCTCTAATAAAAAATGATTGGAGATTTAATGAATGTATTATCATCACAAATTTAGAACCATGTACTATGTGTGCTTC
GGCACTTATACAGGCAAGGATGGGTAAAGTTGTTTTTGGGGCCTACGATAAAAAAAGAGGTGGATTGGGCGGCTCAATTG
ATTTATCGAAGCATAAAAGTTCTCATCACAAAATGGAAATCGTAGGAGGTATTTTAGAAGACGAATGCTGTAAAAATTTA
CAATTATGGTTTAAAAAGTTGAGGACTCAAAAATAG

Upstream 100 bases:

>100_bases
AGTCCCTGAATACGAAGGGAAGTATATATCTTTTTTATTAATTAAATCTTCAGTCATCAGATAAGATATCTATTAATAAG
TTTATTCTTAATATTTGTAA

Downstream 100 bases:

>100_bases
AATATTTTTTTAATTCAGTATCAAATAGGTTTAATAATCTATCTACATTCTCCTCACTTGAGTTAAAGCCCATTAATCCT
ATGCGCCAAACCTTACCAGA

Product: putative cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MRYIFENVNSNYDEQKGTNTLKYTKWMSSILRRSEEIGKVELPICSIILDERGRCIGRGVNRRNINNDPLGHAEIMALRQ
ASLIKNDWRFNECIIITNLEPCTMCASALIQARMGKVVFGAYDKKRGGLGGSIDLSKHKSSHHKMEIVGGILEDECCKNL
QLWFKKLRTQK

Sequences:

>Translated_171_residues
MRYIFENVNSNYDEQKGTNTLKYTKWMSSILRRSEEIGKVELPICSIILDERGRCIGRGVNRRNINNDPLGHAEIMALRQ
ASLIKNDWRFNECIIITNLEPCTMCASALIQARMGKVVFGAYDKKRGGLGGSIDLSKHKSSHHKMEIVGGILEDECCKNL
QLWFKKLRTQK
>Mature_171_residues
MRYIFENVNSNYDEQKGTNTLKYTKWMSSILRRSEEIGKVELPICSIILDERGRCIGRGVNRRNINNDPLGHAEIMALRQ
ASLIKNDWRFNECIIITNLEPCTMCASALIQARMGKVVFGAYDKKRGGLGGSIDLSKHKSSHHKMEIVGGILEDECCKNL
QLWFKKLRTQK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=130, Percent_Identity=42.3076923076923, Blast_Score=115, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19562; Mature: 19562

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYIFENVNSNYDEQKGTNTLKYTKWMSSILRRSEEIGKVELPICSIILDERGRCIGRGV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHCCCCHHHCCC
NRRNINNDPLGHAEIMALRQASLIKNDWRFNECIIITNLEPCTMCASALIQARMGKVVFG
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEC
AYDKKRGGLGGSIDLSKHKSSHHKMEIVGGILEDECCKNLQLWFKKLRTQK
CCCCCCCCCCCCCCCHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRYIFENVNSNYDEQKGTNTLKYTKWMSSILRRSEEIGKVELPICSIILDERGRCIGRGV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHCCCCHHHCCC
NRRNINNDPLGHAEIMALRQASLIKNDWRFNECIIITNLEPCTMCASALIQARMGKVVFG
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEC
AYDKKRGGLGGSIDLSKHKSSHHKMEIVGGILEDECCKNLQLWFKKLRTQK
CCCCCCCCCCCCCCCHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]