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The map label for this gene is accD

Identifier: 126696183

GI number: 126696183

Start: 732862

End: 733743

Strand: Reverse

Name: accD

Synonym: P9301_08451

Alternate gene names: 126696183

Gene position: 733743-732862 (Counterclockwise)

Preceding gene: 126696184

Following gene: 126696182

Centisome position: 44.69

GC content: 35.37

Gene sequence:

>882_bases
GTGTCATTAATCGACTGGTTTGCCGCAAGGCGTAAAGATCAATTTGTTGGAAAAGTTTCGCAAGATGCTGATGAGGGAGA
TGGTTTGTGGGTTAAATGTTCAGAATGTTCTCAAGTAGCCTATAGAAAAGACCTAATTTCAAATTTCAATGTTTGCAGTA
ATTGTGGACACCACAATAGGATAAATAGCGATGAAAGGATAAATATAATTGCTGACAAAAATTCATTCGAAGAGTTTGAT
AGTTTACTAAGTCCTACAGATCCTTTAGGTTTTAAAGATAGAAGATCATATGCTGATCGAATTAAAGAAAGTCAAGCAGG
CACAGGTCTAAGAGATGGAGTCGTAACGGGTATCTGTTCTGTAAATTCAATGCCTTTAGCATTAGCTGTTATGGATTTTA
GATTTATGGGAGGATCCATGGGTTCAGTGGTTGGTGAAAAAATTACAAGGATAATTGAAAGAGCAACTTTAGAAAATTTT
CCTATTCTTATTGTTTGCGCATCAGGTGGAGCAAGGATGCAAGAAGGTATGTTAAGTCTCATGCAAATGGCAAAAATATC
TGGAGCACTAAAAAAGCACAAAGAAAAAAATCTTCTTTATATGCCCTTACTAACTCATCCAACAACTGGGGGAGTAACAG
CAAGCTTTGCAATGTTAGGTGATTTAATTTTGGCAGAACCTAAAGCACTTATTGGATTTGCGGGAAGAAGGGTTATTGAA
CAAACATTAAGAGAAAAATTACCTGATAATTTTCAAACAGCTGAATATCTTCTTGAGCATGGTTTTGTTGATGTAATAGT
GAAAAGGAAAGATCTCAAGACTACTTTGGCTAAGATTTTAAAAATCCATGGAGTAAAAGAACTTGCAGAAGCAAATACAT
AA

Upstream 100 bases:

>100_bases
TACTTTGAGGAGTTTTTAATTTAGAGGATATCAAATTTTTATATATCTTTCTTGATAAAAGTACCTTATTTAGATTTAAA
TAGAAAAAACAGGAAACGTT

Downstream 100 bases:

>100_bases
AATGAAAATATTTTCTAATTTATTTTATTTTTATTTAAGCTTTTTACTTTTTATTTTAAACTTTGCTTCCTATTCATATG
CGATAGGAAATGTTGAATGG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSLIDWFAARRKDQFVGKVSQDADEGDGLWVKCSECSQVAYRKDLISNFNVCSNCGHHNRINSDERINIIADKNSFEEFD
SLLSPTDPLGFKDRRSYADRIKESQAGTGLRDGVVTGICSVNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENF
PILIVCASGGARMQEGMLSLMQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIE
QTLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKTTLAKILKIHGVKELAEANT

Sequences:

>Translated_293_residues
MSLIDWFAARRKDQFVGKVSQDADEGDGLWVKCSECSQVAYRKDLISNFNVCSNCGHHNRINSDERINIIADKNSFEEFD
SLLSPTDPLGFKDRRSYADRIKESQAGTGLRDGVVTGICSVNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENF
PILIVCASGGARMQEGMLSLMQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIE
QTLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKTTLAKILKIHGVKELAEANT
>Mature_292_residues
SLIDWFAARRKDQFVGKVSQDADEGDGLWVKCSECSQVAYRKDLISNFNVCSNCGHHNRINSDERINIIADKNSFEEFDS
LLSPTDPLGFKDRRSYADRIKESQAGTGLRDGVVTGICSVNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENFP
ILIVCASGGARMQEGMLSLMQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQ
TLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKTTLAKILKIHGVKELAEANT

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=261, Percent_Identity=50.5747126436782, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI25147362, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25147359, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_PROM0 (A3PCJ3)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091069.1
- ProteinModelPortal:   A3PCJ3
- SMR:   A3PCJ3
- STRING:   A3PCJ3
- GeneID:   4911201
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_08451
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- BioCyc:   PMAR167546:P9301ORF_0861-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32359; Mature: 32228

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDWFAARRKDQFVGKVSQDADEGDGLWVKCSECSQVAYRKDLISNFNVCSNCGHHNR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCCCCCC
INSDERINIIADKNSFEEFDSLLSPTDPLGFKDRRSYADRIKESQAGTGLRDGVVTGICS
CCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHC
VNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENFPILIVCASGGARMQEGMLSL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
MQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIE
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QTLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKTTLAKILKIHGVKELAEANT
HHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure 
SLIDWFAARRKDQFVGKVSQDADEGDGLWVKCSECSQVAYRKDLISNFNVCSNCGHHNR
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCCCCCC
INSDERINIIADKNSFEEFDSLLSPTDPLGFKDRRSYADRIKESQAGTGLRDGVVTGICS
CCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHC
VNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENFPILIVCASGGARMQEGMLSL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
MQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIE
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QTLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKTTLAKILKIHGVKELAEANT
HHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA