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The map label for this gene is aroB

Identifier: 126696073

GI number: 126696073

Start: 655091

End: 656182

Strand: Reverse

Name: aroB

Synonym: P9301_07351

Alternate gene names: 126696073

Gene position: 656182-655091 (Counterclockwise)

Preceding gene: 126696078

Following gene: 126696071

Centisome position: 39.97

GC content: 29.85

Gene sequence:

>1092_bases
GTGAATAAGAGAAAAATATTAGTCCCATTAGGTGATAAGTCATATGAAGTAACTCTAGAAGCAGGGATACTGAATAATAT
CAGCGAAGAACTTTTAAAAATTGGAATAACAAAGAATAGAAAAATACTTGTGATTTCAAATGAAGAAATATCAAACTTAT
ATGGAGAAAAATTTTTAAATAATTTAAAAGATAATAAATTTCAGGCCAAAATGGTCCTTATCAAGGCTGGAGAATCATAT
AAAAACTTAAAAACCTTAAGTGAAATATATGATGTAGCATTTGAATTTGGCTTAGATAGAAATTCAATAATTATTGCCCT
TGGAGGAGGAATTGTTGGAGATGTAAGTGGTTTTGCAGCTGCGACTTGGCTGAGAGGTATCGAATATATTCAGATTCCAA
CAACATTATTATCAATGGTTGATTCATCTGTGGGAGGAAAAACAGGAGTAAATCATCCAAAAGGTAAGAATTTAATTGGA
GCTTTCAATCAACCTAAAGCAGTTTTTATTGATCCAGAAACTTTAAAAAGTTTGCCCAAAAGAGAATTTAGTGCAGGCAT
GGCCGAAGTAATAAAATACGGAGTAATAAGAGATAAAGAACTTTTCAAATACTTAGAAATTGAAAAAAACAAAAATGAAC
TTATAAATCTCAAAAATGAATATCTAATTAAAATAATTAATAGTTCAATTAAAACAAAGTCTCATATTGTTTCTCAAGAC
GAACATGAAAATGGTGTTAGAGCAATATTGAATTATGGTCATTCTTTTGGTCACGTTATTGAAAATTTATGTGGATACGG
CAAATTTCTACATGGTGAGGCAATATCAATTGGTATGAATATTGCAGGTAAAATAGCAATTGAGAAGGGGTTATGGTCTA
AAGAAGAATTAGAAAGGCAGAAAATTCTATTAGAGAGTTACGATCTTCCTACCGAGATCCCCAAAATAAATAAAGAAGAC
GTTCTAACAATACTTATGGGCGATAAAAAAGTTCGTGATGGCAAAATGAGATTTATATTACCGAAAGAAATTGGTGCTGT
TGATATATATGATGACGTAGAAGATTCATTATTTTTAAAATTTTTTTCTTAA

Upstream 100 bases:

>100_bases
TTCTTAACAACTGAATTTTTAAGGATCTAGAGCTTAGATTTTGCTAATATATAAAGTATTTAATACCAAATATTTATAAA
TTTTAACTAGGTAATCAATT

Downstream 100 bases:

>100_bases
CGCAAGCAGGTTGAATTTATATTCATTTTCTTCTCATTAAACTTTTTAAAAACAAACCACTTGAAATCACCTAAACAAAC
AGGATCTACGAGTCTAAGTA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKNRKILVISNEEISNLYGEKFLNNLKDNKFQAKMVLIKAGESY
KNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAAATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIG
AFNQPKAVFIDPETLKSLPKREFSAGMAEVIKYGVIRDKELFKYLEIEKNKNELINLKNEYLIKIINSSIKTKSHIVSQD
EHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQKILLESYDLPTEIPKINKED
VLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLKFFS

Sequences:

>Translated_363_residues
MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKNRKILVISNEEISNLYGEKFLNNLKDNKFQAKMVLIKAGESY
KNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAAATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIG
AFNQPKAVFIDPETLKSLPKREFSAGMAEVIKYGVIRDKELFKYLEIEKNKNELINLKNEYLIKIINSSIKTKSHIVSQD
EHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQKILLESYDLPTEIPKINKED
VLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLKFFS
>Mature_363_residues
MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKNRKILVISNEEISNLYGEKFLNNLKDNKFQAKMVLIKAGESY
KNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAAATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIG
AFNQPKAVFIDPETLKSLPKREFSAGMAEVIKYGVIRDKELFKYLEIEKNKNELINLKNEYLIKIINSSIKTKSHIVSQD
EHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQKILLESYDLPTEIPKINKED
VLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLKFFS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=357, Percent_Identity=42.0168067226891, Blast_Score=279, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320332, Length=309, Percent_Identity=36.5695792880259, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PROM0 (A3PC83)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090959.1
- ProteinModelPortal:   A3PC83
- SMR:   A3PC83
- STRING:   A3PC83
- GeneID:   4912439
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_07351
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   PMAR167546:P9301ORF_0749-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40672; Mature: 40672

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKNRKILVISNEEISNLYGEKFLN
CCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
NLKDNKFQAKMVLIKAGESYKNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAA
HHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHH
ATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIGAFNQPKAVFIDPETLKSLPK
HHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEEECHHHHHHCCH
REFSAGMAEVIKYGVIRDKELFKYLEIEKNKNELINLKNEYLIKIINSSIKTKSHIVSQD
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
EHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQ
CCCHHHHHHHHCCCHHHHHHHHHHHCCCEECCCEEEECCCCEEEEEEECCCCCHHHHHHH
KILLESYDLPTEIPKINKEDVLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLK
HHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCEEEECCCCCCCEEEE
FFS
ECC
>Mature Secondary Structure
MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKNRKILVISNEEISNLYGEKFLN
CCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
NLKDNKFQAKMVLIKAGESYKNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAA
HHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHH
ATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIGAFNQPKAVFIDPETLKSLPK
HHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEEECHHHHHHCCH
REFSAGMAEVIKYGVIRDKELFKYLEIEKNKNELINLKNEYLIKIINSSIKTKSHIVSQD
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
EHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQ
CCCHHHHHHHHCCCHHHHHHHHHHHCCCEECCCEEEECCCCEEEEEEECCCCCHHHHHHH
KILLESYDLPTEIPKINKEDVLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLK
HHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCEEEECCCCCCCEEEE
FFS
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA