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The map label for this gene is clpB [H]

Identifier: 126695944

GI number: 126695944

Start: 528241

End: 530823

Strand: Reverse

Name: clpB [H]

Synonym: P9301_06061

Alternate gene names: 126695944

Gene position: 530823-528241 (Counterclockwise)

Preceding gene: 126695945

Following gene: 126695942

Centisome position: 32.33

GC content: 30.66

Gene sequence:

>2583_bases
ATGAAAATAGTTCCAAGCGAATTCTCAAATTCTGCTTGGAACTATTTTATTTTTGCCAAAGAAATTGCTTATAAAAATTA
TCAACAAAACGTAGACTCTGATAATTTATTATTAACTCTTATAAAAGAGGACAATATTACAAAAAATATTTTAATAAAAA
ATAATATAAATCTAAAGAATCTTGAGAGGGAAATAATTTCTTCATTAAATGCGAAGGCAAAAATGAAAAATAAACAAGAT
AATTTATATATTGGTGATACTCTTCACAAAATATTTTTAAAGGCGAATGATATTAAAAATAAATTAAATGATGTAGTGAT
ATCAACAGAATACTTAGTTTACGGTTTCGCTTATGATAACAAATATGGATTTCAAATTTTAAATCAAAAAGGTATTCTAG
AATTTCTTGAAATTATAAAGAAAATGAAGTCAGATCCGGCAGTAAAAAATGAATTTAATAGTTCTAATGAGTCTTTGGAA
AAATATGGTATTGATCTAACTCAATCTGCACGAGATGGGATTTTAGACCCAGTTATTGGTAGGGATGAAGAGATTAGAAG
AACAATCCAAATATTGAGTAGAAGAACAAAAAACAACCCTGTTCTTATTGGAGAACCTGGGGTTGGCAAAACGGCCATTG
TTGAAGGGTTAGCTCAGAGAATAATTAATGGCGATGTACCTTCTGCACTACAAGATAGGCAACTAATTTCATTAGATATG
GGCTCACTTATAGCTGGGGCAAAATATCGTGGAGAATTTGAAGAAAGAATAAAAAATATTCTAAAGAAAGTGAAAGAATC
AGACGGAAAGATTATTCTTTTTATTGATGAAATTCATACAGTTGTTGGAGCTGGTGCTAGCGGAGGTTCTTTAGATGCAA
GCAACCTATTAAAACCAATGCTTGCGAGAGGAGAACTTAGATGTATTGGTGCTACAACTATTAATGAACACAAACAAAAT
ATAGAAAAAGATCCTGCTCTAGAACGAAGATTTCAGAAAATAAAAATTGATGCTCCTTCAATAGAAGATACCGTATCAAT
ATTAAGAGGATTGAGAGAAAGATACGAAGTCCATCATAGTGTGAGAATTTCTGATAATGCCTTAGTTGCAGCTGCAACCC
TTAGCGAAAGATATATTAACGATAGATTTCTTCCTGACAAAGCAATAGATCTAATTGATGAAGCAGCCTCAAGATTAAAT
ATGGTCATAACTTCCAAACCTGAAGAAATTGATGAAATTGATCGAAAAGTTCTGCAGTTTGAGATGGAAAAATTATCTTT
AAAAAGGGAAATAGATGATTTTTCTGTAGAAAGATTAGAAAAAATCAATCATGAACTTTTATCTCTTAAAGATAAACAGG
CCGAATTAGGCGCTAAATGGAAAAAAGAAAAAGACGAAATTGATGAGATTAGCACCATAAAAGAAGAAATTGAATCTGTT
CAATTGCAAATAGATCAAGCCAAAAGGAGTTTTGACCTAAACAAAGCAGCAGAATTAGAATTTGGAACTTTAAATTCTTT
GCAAAAAAAATTGAAAGAAAAAAGCGAGTCTCTAGTAAATTCGCAAAAAAATGGAGATACAAGTCTTTTAAGACAAGAGG
TAACTTTTGATGATATTGCAGAAGTTGTTTCAAAGTGGACCTCTATTCCAGTACAGAACTTAAACCAGTCAGAAAAAGAT
AAACTCTTGAGCCTCGAGTCAATCCTCAAAGAAAAAATTATTGGTCAAGATTGTGCAATTAGGGCTGTTGCAGATTCCAT
TAAGAGATCAAGGACTGGTCTAAATGATCCAAGCAAGCCATTAGCCAGTTTTCTCTTTTTAGGTCCAACTGGTGTTGGGA
AAACAGAGCTAAGTAAAGTAACAGCCAAAATAATATTCGATTCAAATTCTTCAATTACAAGACTGGATATGTCTGAATAT
ATGGAAAAGCATTCTGTGAGCAAAATCATAGGTGCGCCTCCCGGATATTTAGGTTTCGAATCAGGCGGCCAACTAACTGA
AGCTGTACGCAAAAATCCTTATTCATTAATACTCCTAGATGAAATAGAGAAAGCTCACAAAGATATTTTAGATATTCTCT
TACAGGTTCTTGATGATGGAATCATTACTGATGGTCAAGGTCGTACAATCAATTTCAAAAATTCAATCATTGTTCTCACA
AGTAATTTAGGAAGTCAATCAATAAATGATTTATCAGTTAGAAAAGAAGATAAAAATGAAATTAAAAAAGTTGTAGATAA
TGAAATTAAAAAATTTTTCAAGCCTGAGTTTTTAAATCGACTTGATGAAATAGTTATTTTTAATAATTTAGAATTAAGTG
ACATAAAAGAAATTGCAAAAATCCAGCTTCAACATTTAGAAAAAAGACTTAACAAAAAAAACTTAAAATTCAAAATTACG
GATGAAGCAATTAACCAACTTGTCGAAAATAGTTTCGATCATGCCTATGGTGCAAGACCTTTAAAAAGAATTATTCAAAA
ACAAATTGAGACAAAAATTTCAAATAATATATTGAATAATCATTACCTTAATAAAGACGAGATTAATATTTATCTGGTTA
ATGGAGAGATAAATGTTGATTAA

Upstream 100 bases:

>100_bases
TGGTAGGTAAAGTTGTTGTTGAATAAATCTTAAATCTTCTAAATTTTTAAAAACTCTTTTTGACTGAATATTTATTACCA
TCATATTCAAATTTTGATTG

Downstream 100 bases:

>100_bases
ATCTCTAACTAAAGAATCCTATATGAATTTACAATTAACAACTTTAATCTAAGATTTGAACCAATCAGGAATTTTCTCAT
AACTTGCTTTATTCGATTTA

Product: ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MKIVPSEFSNSAWNYFIFAKEIAYKNYQQNVDSDNLLLTLIKEDNITKNILIKNNINLKNLEREIISSLNAKAKMKNKQD
NLYIGDTLHKIFLKANDIKNKLNDVVISTEYLVYGFAYDNKYGFQILNQKGILEFLEIIKKMKSDPAVKNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRQLISLDM
GSLIAGAKYRGEFEERIKNILKKVKESDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIEDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKREIDDFSVERLEKINHELLSLKDKQAELGAKWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDCAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDKNEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELSDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVNGEINVD

Sequences:

>Translated_860_residues
MKIVPSEFSNSAWNYFIFAKEIAYKNYQQNVDSDNLLLTLIKEDNITKNILIKNNINLKNLEREIISSLNAKAKMKNKQD
NLYIGDTLHKIFLKANDIKNKLNDVVISTEYLVYGFAYDNKYGFQILNQKGILEFLEIIKKMKSDPAVKNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRQLISLDM
GSLIAGAKYRGEFEERIKNILKKVKESDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIEDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKREIDDFSVERLEKINHELLSLKDKQAELGAKWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDCAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDKNEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELSDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVNGEINVD
>Mature_860_residues
MKIVPSEFSNSAWNYFIFAKEIAYKNYQQNVDSDNLLLTLIKEDNITKNILIKNNINLKNLEREIISSLNAKAKMKNKQD
NLYIGDTLHKIFLKANDIKNKLNDVVISTEYLVYGFAYDNKYGFQILNQKGILEFLEIIKKMKSDPAVKNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRQLISLDM
GSLIAGAKYRGEFEERIKNILKKVKESDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIEDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKREIDDFSVERLEKINHELLSLKDKQAELGAKWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDCAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDKNEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELSDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVNGEINVD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=37, Blast_Score=198, Evalue=2e-50,
Organism=Escherichia coli, GI1788943, Length=827, Percent_Identity=49.9395405078597, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=267, Percent_Identity=55.4307116104869, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6320464, Length=799, Percent_Identity=47.3091364205257, Blast_Score=726, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=708, Percent_Identity=44.2090395480226, Blast_Score=605, Evalue=1e-173,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97402; Mature: 97402

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVPSEFSNSAWNYFIFAKEIAYKNYQQNVDSDNLLLTLIKEDNITKNILIKNNINLKN
CCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCHHH
LEREIISSLNAKAKMKNKQDNLYIGDTLHKIFLKANDIKNKLNDVVISTEYLVYGFAYDN
HHHHHHHHCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEECC
KYGFQILNQKGILEFLEIIKKMKSDPAVKNEFNSSNESLEKYGIDLTQSARDGILDPVIG
CCCCEEECCCCHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCCHHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRQLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCHHCCH
GSLIAGAKYRGEFEERIKNILKKVKESDGKIILFIDEIHTVVGAGASGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKIDAPSIEDTVSILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKREIDDFSVERLEKINHELLSLKDKQAELGAKWKKEKDEIDEISTIKEEIESV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKDKLLSLESILKEKIIGQDCAIRAVADSIKRSRTGLNDPSKP
HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHHCCCCCCCHHHHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDKNEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELSDIKEIAK
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQHLEKRLNKKNLKFKITDEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNN
HHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHC
HYLNKDEINIYLVNGEINVD
CCCCCCCEEEEEEECEEECC
>Mature Secondary Structure
MKIVPSEFSNSAWNYFIFAKEIAYKNYQQNVDSDNLLLTLIKEDNITKNILIKNNINLKN
CCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCHHH
LEREIISSLNAKAKMKNKQDNLYIGDTLHKIFLKANDIKNKLNDVVISTEYLVYGFAYDN
HHHHHHHHCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEECC
KYGFQILNQKGILEFLEIIKKMKSDPAVKNEFNSSNESLEKYGIDLTQSARDGILDPVIG
CCCCEEECCCCHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCCHHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRQLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCHHCCH
GSLIAGAKYRGEFEERIKNILKKVKESDGKIILFIDEIHTVVGAGASGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKIDAPSIEDTVSILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKREIDDFSVERLEKINHELLSLKDKQAELGAKWKKEKDEIDEISTIKEEIESV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKDKLLSLESILKEKIIGQDCAIRAVADSIKRSRTGLNDPSKP
HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHHCCCCCCCHHHHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDKNEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELSDIKEIAK
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQHLEKRLNKKNLKFKITDEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNN
HHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHC
HYLNKDEINIYLVNGEINVD
CCCCCCCEEEEEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]