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The map label for this gene is argB

Identifier: 126695864

GI number: 126695864

Start: 459607

End: 460458

Strand: Reverse

Name: argB

Synonym: P9301_05261

Alternate gene names: 126695864

Gene position: 460458-459607 (Counterclockwise)

Preceding gene: 126695865

Following gene: 126695863

Centisome position: 28.04

GC content: 33.92

Gene sequence:

>852_bases
ATGAATGATTCTCAAAGAGTATCAATATTAAGTGAAGCACTTCCATATATACAAAGTTTCTCAGGCAGAAAAATTGTTAT
CAAGTATGGCGGTTCTGTTATGGAGGATGATGATTTAAAAAATGCTTTTTTTAGAGATATAGCACTTTTATCAACTGTGG
GGGTTTGTCCGATAGTAATTCATGGAGGTGGACCCGAGATTAATAATTGGTTAAAGAAATTAGAAATATCTCCTAAATTT
GAAAATGGATTAAGAATTACTGATCAAAAAACAATGGAAATTGTCGAGATGGTTCTAATGGGTAGAGTTAACAAACAAAT
TGTAAAAGGCATTAATAAAACTGGATCCTTAGCAGTGGGAATATCAGGTCTTGATGGCAACTTAATTCAATCAAGAGAAC
TAGGAGATGGGAGCCATGGGTTAGTGGGTGAGGTCACAAAAATCAATCCTGAAATATTAGATCCTCTTATTTCTAAAGGA
TATATCCCTATTATTTCAAGTATTGGATCAACAGTGGAGGGGATTTCACATAACATTAATGCAGATTTTGTTGCTGGAGA
AATTGCTGCTGCAATAAGTGCGGAAAAACTTATTCTTCTTACTGATACTCAAGGGATTTTAAAAGAAAAAGATAATAAAA
ATAGTCTTGTCGAAAAAACGAATCTCAAAGAGGCAAGAGATTTAATTGATAAAAAAATTGTGACTGAAGGTATGATTCCA
AAGACAGAATGCTGCATTAGGGCTTTAGCTCAAGGAGTCAAAGCTGCTCACATCATTGATGGAAGAGTACAACATTCGTT
ACTTCTTGAAATTTTTACAAATACCGGAATAGGGACAATGATAGTCGCTTAA

Upstream 100 bases:

>100_bases
AATAAAAAAGAATTTGATTTTATTCTCTTTTATTGAATATAGGGATATATTTGTAAAAACCTAACTTCTCAATTCAATCA
AGTTTTAATGATTTTTAATA

Downstream 100 bases:

>100_bases
ACTATGAAAACTTATGAGCAAGTTTTAGAAACAGTAGAACTTGCTTTAGCAAAAGGTGAGTATCATTATTGTATTGAATT
TCTTTTACCTTTAATCGAAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLKKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTVEGISHNINADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIP
KTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA

Sequences:

>Translated_283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLKKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTVEGISHNINADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIP
KTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA
>Mature_283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLKKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTVEGISHNINADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIP
KTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=26.1484098939929, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693208, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320913, Length=276, Percent_Identity=30.0724637681159, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PROM0 (A3PBM4)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090750.1
- ProteinModelPortal:   A3PBM4
- SMR:   A3PBM4
- STRING:   A3PBM4
- GeneID:   4912162
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_05261
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   PMAR167546:P9301ORF_0539-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30526; Mature: 30526

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: BINDING 85-85 BINDING 178-178

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
HGGGPEINNWLKKLEISPKFENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVG
ECCCCCHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTVEGISHNIN
EECCCCCEEECCCCCCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIP
CHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCC
KTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA
HHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
HGGGPEINNWLKKLEISPKFENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVG
ECCCCCHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTVEGISHNIN
EECCCCCEEECCCCCCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIP
CHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCC
KTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA
HHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA