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The map label for this gene is cat1 [H]

Identifier: 126447851

GI number: 126447851

Start: 1954534

End: 1956048

Strand: Reverse

Name: cat1 [H]

Synonym: BMA10247_A2021

Alternate gene names: 126447851

Gene position: 1956048-1954534 (Counterclockwise)

Preceding gene: 126447097

Following gene: 126445956

Centisome position: 83.14

GC content: 66.93

Gene sequence:

>1515_bases
ATGCCAACCTCTCGTATCCTCGCCCCCAGCCTGCGCTCCCTCGTTCGCACCGCCGACGAGGCCGCCGCGCTGATCGGCCC
GAACATGACCGTCGCGATGAGCGGCTTCACCGGCTCCGGCTATCCGAAGGCGGTGCCGGCCGCGCTCGCCGCGCGGATCG
CGGCTTCCCACGCGCGCGGCGAAGATTTCCGCATCAACGTGCTGACGGGCGCGTCGACCGCGCCCGAGCTGGACGGCGCG
CTCGCGAAGGCGGACGGTATCTCGATGCGGCTGCCGTACCAGTCCGATCCGACGCTGCGCGAGAAGATCAACGCGGGCGA
GCTCGACTATCAGGACATCCACCTGAGCCACGTCGCGCAGTACGCGTGGTTCGGCCTGTTCGGCGAGCTGGACGTCGCGA
TCGTCGAGGTCGCGGGCATTCGCGAGGACGGGCGCCTGATTCCGTCGGCGTCGGTCGGCAACAACAAGACGTGGCTCGAC
CAGGCCAAGCGCGTGATCCTCGAGGTGAACGCGCGCCAGCCGCTCGGTCTCGACGGGATGCACGACATCTATTACGGCAC
CGCGCTGCCGCCGAACCGCAAGCCGATTCCGCTCGTGAAGAGCGACGACCGGATCGGCGAGCCGTATCTGCGCTGCCCGG
CCGAGAAGATCGTCGCGATCGTCGAGACCGACGCGCCGGACCGCAGCAACGCGTTCGCCGCGCCGGACGAGACCTCCAAG
CAGATCGCCGGACTCCTGATCGATTTCCTGCGTCACGAGATCAAGCGCGGCCGTCTGCCCGAACACCTGCTGCCGCTGCA
GTCCGGCGTCGGCAACATCACGAACGCGGTGCTCGCCGGCCTCGGCGAAGGCGGTTTCTCGAACCTGAGCGCGTATACGG
AAGTGATTCAGGACGGCATGCTCGATCTGCTCGCGAACGGTACGCTGAGCTTCGCGTCGGCGACCGCGCTGTCGCTCAGC
CCGGATGCGGTGAAGCGCTTCGCCGACGAGATCGATACGTTCCGCTCGAAGATCGTGCTGCGGCCGCAGGAAATCAGCAA
CCATCCGGAGCTCGTGCGGCGCCTGGGCATCATCGCGATGAACGGGATGATCGAGGCCGATATCTACGGCAACGTGAACT
CGACGCACGTGATGGGCACGAGGATTCAGAACGGGATCGGCGGCTCCGGCGATTTCGCGCGCAACGGCTATCTGTCGTGC
TTCATGTCGGCGAGCACTGCCAAGGGCGGCGCCATTTCGCGGATCGTGCCGATGGCGAGCCACGTTGACCATACCGAGCA
CGACGTCGCGGTCGTCGTGACCGAGCAGGGGCTCGCGGATCTGCGTGGACTGTCGCCGAAGCAGCGCGCGCGCAAGGTCA
TCGCGAACTGCGCGCATCCCGATTACCGGCCGATGCTCGAAGACTACTTCGAGCGCGCGAGCCGCGAGAGCTTCGGCAAG
CAGACGCCGCATCTGCTCGGCGAAGCGCTGTCGTGGCACGAGCGCTACGTGCGGACCGGATCGATGAAAGCCTGA

Upstream 100 bases:

>100_bases
CCTCTTGCGATTGCCGCAGGCGCCGGGAGCGCGCGCCACTCCGGAGACACCCCTGCGGCGCAGCGTCGCCAGATCTACTA
CAACCGTTCGACATTCAGCC

Downstream 100 bases:

>100_bases
CGCCCGGCGCGGCAACGCACCGGGCGGGCGGCAGCGCCCGTTCGGACCGGCGATTGAAACGGCGCGGCACCGCAAGGTGG
CCGCGCCGTTTCGTCAATGC

Product: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAVPAALAARIAASHARGEDFRINVLTGASTAPELDGA
LAKADGISMRLPYQSDPTLREKINAGELDYQDIHLSHVAQYAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLD
QAKRVILEVNARQPLGLDGMHDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVETDAPDRSNAFAAPDETSK
QIAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGLGEGGFSNLSAYTEVIQDGMLDLLANGTLSFASATALSLS
PDAVKRFADEIDTFRSKIVLRPQEISNHPELVRRLGIIAMNGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLSC
FMSASTAKGGAISRIVPMASHVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCAHPDYRPMLEDYFERASRESFGK
QTPHLLGEALSWHERYVRTGSMKA

Sequences:

>Translated_504_residues
MPTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAVPAALAARIAASHARGEDFRINVLTGASTAPELDGA
LAKADGISMRLPYQSDPTLREKINAGELDYQDIHLSHVAQYAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLD
QAKRVILEVNARQPLGLDGMHDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVETDAPDRSNAFAAPDETSK
QIAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGLGEGGFSNLSAYTEVIQDGMLDLLANGTLSFASATALSLS
PDAVKRFADEIDTFRSKIVLRPQEISNHPELVRRLGIIAMNGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLSC
FMSASTAKGGAISRIVPMASHVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCAHPDYRPMLEDYFERASRESFGK
QTPHLLGEALSWHERYVRTGSMKA
>Mature_503_residues
PTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAVPAALAARIAASHARGEDFRINVLTGASTAPELDGAL
AKADGISMRLPYQSDPTLREKINAGELDYQDIHLSHVAQYAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLDQ
AKRVILEVNARQPLGLDGMHDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVETDAPDRSNAFAAPDETSKQ
IAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGLGEGGFSNLSAYTEVIQDGMLDLLANGTLSFASATALSLSP
DAVKRFADEIDTFRSKIVLRPQEISNHPELVRRLGIIAMNGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLSCF
MSASTAKGGAISRIVPMASHVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCAHPDYRPMLEDYFERASRESFGKQ
TPHLLGEALSWHERYVRTGSMKA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=487, Percent_Identity=48.2546201232033, Blast_Score=455, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17538151, Length=489, Percent_Identity=24.7443762781186, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319456, Length=513, Percent_Identity=43.859649122807, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54378; Mature: 54246

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAVPAALAARIAASHARG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
EDFRINVLTGASTAPELDGALAKADGISMRLPYQSDPTLREKINAGELDYQDIHLSHVAQ
CCEEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHH
YAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLDQAKRVILEVNARQPLGLDGM
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCCCCCCC
HDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVETDAPDRSNAFAAPDETSK
HHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHEEEEEECCCCCCCCCCCCCCHHHH
QIAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGLGEGGFSNLSAYTEVIQDGM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LDLLANGTLSFASATALSLSPDAVKRFADEIDTFRSKIVLRPQEISNHPELVRRLGIIAM
HHHHHCCCCHHHHCEEECCCHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHHHHHC
NGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLSCFMSASTAKGGAISRIVPMAS
CCEEEEEEECCCCCCEEEHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
HVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCAHPDYRPMLEDYFERASRESFGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
QTPHLLGEALSWHERYVRTGSMKA
CCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PTSRILAPSLRSLVRTADEAAALIGPNMTVAMSGFTGSGYPKAVPAALAARIAASHARG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
EDFRINVLTGASTAPELDGALAKADGISMRLPYQSDPTLREKINAGELDYQDIHLSHVAQ
CCEEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHH
YAWFGLFGELDVAIVEVAGIREDGRLIPSASVGNNKTWLDQAKRVILEVNARQPLGLDGM
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCCCCCCC
HDIYYGTALPPNRKPIPLVKSDDRIGEPYLRCPAEKIVAIVETDAPDRSNAFAAPDETSK
HHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHEEEEEECCCCCCCCCCCCCCHHHH
QIAGLLIDFLRHEIKRGRLPEHLLPLQSGVGNITNAVLAGLGEGGFSNLSAYTEVIQDGM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LDLLANGTLSFASATALSLSPDAVKRFADEIDTFRSKIVLRPQEISNHPELVRRLGIIAM
HHHHHCCCCHHHHCEEECCCHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHHHHHC
NGMIEADIYGNVNSTHVMGTRIQNGIGGSGDFARNGYLSCFMSASTAKGGAISRIVPMAS
CCEEEEEEECCCCCCEEEHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
HVDHTEHDVAVVVTEQGLADLRGLSPKQRARKVIANCAHPDYRPMLEDYFERASRESFGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
QTPHLLGEALSWHERYVRTGSMKA
CCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]