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The map label for this gene is gph-2 [C]

Identifier: 126447367

GI number: 126447367

Start: 1840843

End: 1841571

Strand: Direct

Name: gph-2 [C]

Synonym: BMA10247_A1909

Alternate gene names: 126447367

Gene position: 1840843-1841571 (Clockwise)

Preceding gene: 126447297

Following gene: 126445607

Centisome position: 78.24

GC content: 66.8

Gene sequence:

>729_bases
ATGACGACGTCGCCTCTCAATGGCGCGCCGCGCATCGAAGCGGCGCTCATCGATCTCGACGGCACGATGGTCGATACCGC
AGACGATTTCACGGCCGGCCTGAACGCGATGCTCGCGCAGCTCGATGCCGAGGAGACGACGCGCGAGGAAGTGATGCGCT
ATGTCGGCAAGGGTTCGGAGAACCTGATCCAGTGCGTGCTGACGCCGCGCTTTTCCGCAGACGACGCGAACGCGCGCTTC
GACGAGGCGCTCGCGCTCTATCAGGCCGAATACGCGAAGATCAACGGCCGCCACACGCGGCTCTACCCGGACGTCGACGC
AGGCTTGCGGGCGATGCGTGAAGCGGGCGTCAAGCTCGCATGCGTGACGAACAAGCCGTGCCGGTTCGCGGTCGAGCTGC
TCGCGCAGTACGGCCTGTCCGGCCATTTCTCCGCGGTGTTCGGCGGCGACAGCGTGCCGCGCAAGAAGCCCGATCCGGCG
CCGATGCTCGCCGCATGCGCCGCGCTCGGCGTCGCGCCGCGCACGGCGGTCGCGATCGGCGATTCGGAGAACGACGCGCT
CGCGGGCCGCGCGGCCGGGATGGCGACACTGACGGTGCCGTACGGCTACAACCACGGCAACGCTATACAAACGATCGAAT
CGGATGGTATAGTCGATTCGCTTCTCGCCGCCGCACGGCTCATCGCCGCGCACAATTCGGCAGGATCAGCGGCAAGATCA
GCCATCTGA

Upstream 100 bases:

>100_bases
CGTTCGTCGCGGGCTCGGCGATCTTCGGCAAGCCCGACTATCGGCAGGTGATCGGCGAGATGCGCGACGCGCTCGCCACC
GTCGGGCGCGCGTGCGCACG

Downstream 100 bases:

>100_bases
CTTTTTCTTCCATCCGCATGTTTCTGAACAAAAAACGGAGTCTGAGCAGCATCGACCGGGGAGCCTGGCCCTGGCGTCGC
TGGTCGCGCCAACCTCGATG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDANARF
DEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYGLSGHFSAVFGGDSVPRKKPDPA
PMLAACAALGVAPRTAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAARS
AI

Sequences:

>Translated_242_residues
MTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDANARF
DEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYGLSGHFSAVFGGDSVPRKKPDPA
PMLAACAALGVAPRTAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAARS
AI
>Mature_241_residues
TTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSENLIQCVLTPRFSADDANARFD
EALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLACVTNKPCRFAVELLAQYGLSGHFSAVFGGDSVPRKKPDPAP
MLAACAALGVAPRTAVAIGDSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAARSA
I

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=247, Percent_Identity=32.3886639676113, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25313; Mature: 25182

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSE
CCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
NLIQCVLTPRFSADDANARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLA
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEE
CVTNKPCRFAVELLAQYGLSGHFSAVFGGDSVPRKKPDPAPMLAACAALGVAPRTAVAIG
EECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
DSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAARS
CCCCCCHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHC
AI
CC
>Mature Secondary Structure 
TTSPLNGAPRIEAALIDLDGTMVDTADDFTAGLNAMLAQLDAEETTREEVMRYVGKGSE
CCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
NLIQCVLTPRFSADDANARFDEALALYQAEYAKINGRHTRLYPDVDAGLRAMREAGVKLA
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEE
CVTNKPCRFAVELLAQYGLSGHFSAVFGGDSVPRKKPDPAPMLAACAALGVAPRTAVAIG
EECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
DSENDALAGRAAGMATLTVPYGYNHGNAIQTIESDGIVDSLLAAARLIAAHNSAGSAARS
CCCCCCHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHC
AI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA