BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

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The map label for this gene is fabG3 [H]

Identifier: 126446807

GI number: 126446807

Start: 920315

End: 921085

Strand: Direct

Name: fabG3 [H]

Synonym: BMA10247_A0973

Alternate gene names: 126446807

Gene position: 920315-921085 (Clockwise)

Preceding gene: 126446690

Following gene: 126447262

Centisome position: 39.12

GC content: 73.02

Gene sequence:

>771_bases
ATGAGCGCGCCCGTGCAGGCGATCGCGCTCGCCGGCCGCCGCGTGCTCGTCACGGGCGGCGCGCGCGGGCTCGGCGCGGC
ATTCGTCGAGGCGCTCGTCGCGGCGGGCGCGAAAGTGGCGTTCGGCGACGTGCTCGACGCGGAAGGCCGTGCGCTCGCGC
AGCGCCTGCGCGACGCGGGGCACGACGCGCACTTCATCGCGCTCGACCTCGCGGCTCCCGCCAGCGTGACCGCCTTCGTC
GACGAAGGCGCGCGCGTGCTCGGCGGCCTCGACGGCCTCGTCAACAACGCGGCGATCACGAACTCGGGCGGCAAGCGCGC
AACCGAGCTGTCGATCGACACGTGGGACGCGGTGATGAACGTCAACGCGCGCGGCGTCTGGCTCGCGTGCAACGCGGCGC
TGCCGCATCTCGCGCGCTCGGGGCGCGGCGCGATCGTGAATCTCGCGTCCGACACCGCGTTGTGGGGCGCGCCGAAGCTG
CTCGCCTACGTCGCGAGCAAAGGCGCGGTGATCGCGATGACGCACGCGCTCGCGCGCGAGTTCGGCGAACAGGGCGTGAC
GGTCAACGCGGTCGCGCCGGGCCTGACCGAAGTCGAGGCGACCGCGTACGTGCCGGCCGAGCGCCACGAATACTACTTGC
AGGGCCGCGCGCTACCGCGCGCGCAAGTGCCGGCGGACGTGACGGGGCCGGTGCTGTTCTTGCTGTCCGACGCCGCGCGT
TTCGTCACGGGCCAGTTGCTGCCCGTGAACGGCGGCTTCGTGATGCATTGA

Upstream 100 bases:

>100_bases
GCGTCACGCGCGTGCGGCGGATGCTGCGCCAGCGCGCGCAGGAGCATCTCGCCGCGCTCGACGCGCATCGCGCGGCGCAG
GCCGACGCGGCGGAGCGCGC

Downstream 100 bases:

>100_bases
TCGATTGTTAGCACTTAGCACTCTTGAAGGAGATGACGATGACGGACGCCGATATCGAGCGTAAATCGTGGGACCAGCCG
GCGGGCGAAAGCTTCGCCCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSAPVQAIALAGRRVLVTGGARGLGAAFVEALVAAGAKVAFGDVLDAEGRALAQRLRDAGHDAHFIALDLAAPASVTAFV
DEGARVLGGLDGLVNNAAITNSGGKRATELSIDTWDAVMNVNARGVWLACNAALPHLARSGRGAIVNLASDTALWGAPKL
LAYVASKGAVIAMTHALAREFGEQGVTVNAVAPGLTEVEATAYVPAERHEYYLQGRALPRAQVPADVTGPVLFLLSDAAR
FVTGQLLPVNGGFVMH

Sequences:

>Translated_256_residues
MSAPVQAIALAGRRVLVTGGARGLGAAFVEALVAAGAKVAFGDVLDAEGRALAQRLRDAGHDAHFIALDLAAPASVTAFV
DEGARVLGGLDGLVNNAAITNSGGKRATELSIDTWDAVMNVNARGVWLACNAALPHLARSGRGAIVNLASDTALWGAPKL
LAYVASKGAVIAMTHALAREFGEQGVTVNAVAPGLTEVEATAYVPAERHEYYLQGRALPRAQVPADVTGPVLFLLSDAAR
FVTGQLLPVNGGFVMH
>Mature_255_residues
SAPVQAIALAGRRVLVTGGARGLGAAFVEALVAAGAKVAFGDVLDAEGRALAQRLRDAGHDAHFIALDLAAPASVTAFVD
EGARVLGGLDGLVNNAAITNSGGKRATELSIDTWDAVMNVNARGVWLACNAALPHLARSGRGAIVNLASDTALWGAPKLL
AYVASKGAVIAMTHALAREFGEQGVTVNAVAPGLTEVEATAYVPAERHEYYLQGRALPRAQVPADVTGPVLFLLSDAARF
VTGQLLPVNGGFVMH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=35.9307359307359, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=27.3469387755102, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=30.7984790874525, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI15277342, Length=147, Percent_Identity=34.6938775510204, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=29.2682926829268, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=26.2548262548263, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723750, Length=171, Percent_Identity=27.4853801169591, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=27.8008298755187, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=27.3469387755102, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI20149619, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=30.0395256916996, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=32.5396825396825, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=34.8178137651822, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.8367346938775, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.9803921568627, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=26.6932270916335, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=27.1604938271605, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787526, Length=246, Percent_Identity=28.4552845528455, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.0196078431373, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=32.2834645669291, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=31.8897637795276, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=27.5193798449612, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=33.6585365853659, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.4, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=28.1368821292776, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.3893129770992, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.3436293436293, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.8195488721804, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=217, Percent_Identity=30.8755760368664, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.0676691729323, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=24.2307692307692, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=25, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=26.3565891472868, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=26.063829787234, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=25.9398496240602, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=184, Percent_Identity=26.6304347826087, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=28.5, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=26.1083743842365, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=35.7142857142857, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=33.6, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=36.9047619047619, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=32.2709163346614, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=32.3886639676113, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737361, Length=216, Percent_Identity=31.0185185185185, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=26.3959390862944, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=32.5396825396825, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221331218, Length=242, Percent_Identity=29.7520661157025, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665243, Length=242, Percent_Identity=29.7520661157025, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=243, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665247, Length=243, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=28.0172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.53 [H]

Molecular weight: Translated: 26248; Mature: 26117

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPVQAIALAGRRVLVTGGARGLGAAFVEALVAAGAKVAFGDVLDAEGRALAQRLRDAG
CCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCC
HDAHFIALDLAAPASVTAFVDEGARVLGGLDGLVNNAAITNSGGKRATELSIDTWDAVMN
CCCEEEEEEECCCCEEEEEHHCCHHHHHHHHHHHCCCEEECCCCCEEEEEECCHHHHHEE
VNARGVWLACNAALPHLARSGRGAIVNLASDTALWGAPKLLAYVASKGAVIAMTHALARE
CCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHH
FGEQGVTVNAVAPGLTEVEATAYVPAERHEYYLQGRALPRAQVPADVTGPVLFLLSDAAR
HHHCCCEEEEECCCCCEEEEEEECCCHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
FVTGQLLPVNGGFVMH
HHCCEEEEECCCEEEC
>Mature Secondary Structure 
SAPVQAIALAGRRVLVTGGARGLGAAFVEALVAAGAKVAFGDVLDAEGRALAQRLRDAG
CCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCC
HDAHFIALDLAAPASVTAFVDEGARVLGGLDGLVNNAAITNSGGKRATELSIDTWDAVMN
CCCEEEEEEECCCCEEEEEHHCCHHHHHHHHHHHCCCEEECCCCCEEEEEECCHHHHHEE
VNARGVWLACNAALPHLARSGRGAIVNLASDTALWGAPKLLAYVASKGAVIAMTHALARE
CCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHH
FGEQGVTVNAVAPGLTEVEATAYVPAERHEYYLQGRALPRAQVPADVTGPVLFLLSDAAR
HHHCCCEEEEECCCCCEEEEEEECCCHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
FVTGQLLPVNGGFVMH
HHCCEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]