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The map label for this gene is 126446775

Identifier: 126446775

GI number: 126446775

Start: 1020135

End: 1021754

Strand: Reverse

Name: 126446775

Synonym: BMA10247_A1078

Alternate gene names: NA

Gene position: 1021754-1020135 (Counterclockwise)

Preceding gene: 126447123

Following gene: 126445744

Centisome position: 43.43

GC content: 71.48

Gene sequence:

>1620_bases
ATGTCCGTCCTCGTTCCGCTCGCCGGTTGCGGCGGCGGTGGCGACGGAGGCGGAAGCGGCACGCCGTCGGCCGCCGCGCA
GCCGACCCCCGCGCCGGCACCGGCGCCGGCCCCGGCACCCGCGCCGAGCTCGGGTTCGTCGCAATCCACCAATTCGTCGA
CCTCGACGGCGGCCTGCCCCGTCACGCAGGCCGCCTCGACCGCCGCCGGCGAAACGCTCGTCACCCGCACCGTTTCGCAC
GAAGCACCCGTCGACCATCTGATCGTCAAGCTGCAACGCACGGCGGCGGCGAGCGCATCCGGCGCGCGCATCATGGCCGC
GGCGAACGACGCGGCCCGACTCGATTCGGTGATCCAGCGCGTGATGTCGCAATGGAGCGCGAAGAGCGGCGCCGTTCGCT
CGTATGCGCAGAACATCGCGCCGACGAACGCGGTGCAGGTGGAACGGACGATGTCGGACGGTGCCGCGCTGCTCGCGCTC
GGACAAAAGATGAGCGCGGATAATGCCGGCGCTCTCGCGCAAACGTTCGCGGCCGATCCGGACGTCGCCTATGCGGAGCC
CGACCGGCGCGTGTTCGCCCGCACGGTGGCGACCGACCCGGACTACGCGCAGCAGTGGAACTACTTCGATCCGGCGGCCG
GCATCAATCTGCCGGACGCATGGAACGTGACGAACGGCCTGCCGAGCGTCGTCACCGCGGTGCTCGACACCGGCTATCGC
CCGCATCCGGACATCATCGCGAACCTGCTGCCGGGCTACGATTTCATCTCCGACATCAACACCGGCAACAACGGCCACGG
CCGCGGCCCGGACGCGACCGACCCGGGCGACTGGGTCACGCAGCAGGAACTGACCGATCCGTCGAGCCCGTTCTACCAAT
GCGCGAGCGCGCCGTCGAACAGCAGCTGGCACGGCACGCAGGTCGCCGGCATCATCGGCGCCGCCGCGAACAACGGCATC
GGCATCGCGGGCGTCAGCTGGTACGGCAAGATCCTGCCCGTGCGCGTGCTCGGCAAGTGCGGCGGCACGACGAGCGACAT
CGCCGACGCGATGCGCTGGGCGGCGGGCATTCCCGTCGCGGGCGCGCCGACGAACCTCACGCCGGCGAAGGTGATCAACC
TGAGCCTCGGCGGCAGCGGCCCGTGCGGCGACACGTTCCAGCAGGCGATCAACGACGTGATCGCGCGCGGCACGACCGTC
GTCGTCTCGGCCGGCAACGACGGCCAGGCGACGACGCTGGACCGCCCGGCCAACTGCAAGGGCGTGATCTCGGTCGGCGC
GACCGACAGCACCGGCCAGCGCGCGTGGTACAGCAACTTCGGCTCGGACATCACGCTGAGCGCGCCGGGCTCGAACATCC
TGTCGACGAGCAATGCGGGCACCACGGTGCCGACCACCGACGCGTACGGCACGCACAGCGGCACGAGCCTCGCCGCGCCG
CAGGTGGCGGGCGTCGCCTCGCTGATGCTCGCGGTCAACCCGAACCTCACGCCCGCGCAGATCGCGCAGAAGCTCGCGAG
CACCGCGCGGCCGTCGCCGGCCACCGCATCCTGCCTCGCGCGCGCGCCGGGCGCGGGCATCGTCGACGCCGGCACGGTGG
TTGCGTCCGCAACGAAATAG

Upstream 100 bases:

>100_bases
GTATCGAACCCAAGAGTGGAGAGGCCCCATGAACAAGAAATGTAGTAATCCTGAACAGACGCGGCTTGGCCAGGTCCGTG
CCGTCGCCGGCATTCTCTCC

Downstream 100 bases:

>100_bases
CGTCGCGTCCCGAACGCGCTCTTGCGGCGGCCGCCCGAACGGGCGGCCGTCTTTCTTCGGTTCGCGGCCGCGCCGGCGGC
AATGCGCCACCTCGCGCGCA

Product: serine metalloprotease MrpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTSTAACPVTQAASTAAGETLVTRTVSH
EAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAALLAL
GQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGINLPDAWNVTNGLPSVVTAVLDTGYR
PHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCASAPSNSSWHGTQVAGIIGAAANNGI
GIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSLGGSGPCGDTFQQAINDVIARGTTV
VVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILSTSNAGTTVPTTDAYGTHSGTSLAAP
QVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVASATK

Sequences:

>Translated_539_residues
MSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTSTAACPVTQAASTAAGETLVTRTVSH
EAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAALLAL
GQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGINLPDAWNVTNGLPSVVTAVLDTGYR
PHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCASAPSNSSWHGTQVAGIIGAAANNGI
GIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSLGGSGPCGDTFQQAINDVIARGTTV
VVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILSTSNAGTTVPTTDAYGTHSGTSLAAP
QVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVASATK
>Mature_538_residues
SVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTSTAACPVTQAASTAAGETLVTRTVSHE
APVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAALLALG
QKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGINLPDAWNVTNGLPSVVTAVLDTGYRP
HPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCASAPSNSSWHGTQVAGIIGAAANNGIG
IAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSLGGSGPCGDTFQQAINDVIARGTTVV
VSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILSTSNAGTTVPTTDAYGTHSGTSLAAPQ
VAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVASATK

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505577, Length=421, Percent_Identity=28.2660332541568, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20336180, Length=420, Percent_Identity=27.8571428571429, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20336182, Length=412, Percent_Identity=27.4271844660194, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI20336184, Length=412, Percent_Identity=27.4271844660194, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI27894285, Length=423, Percent_Identity=27.6595744680851, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI20336190, Length=423, Percent_Identity=27.6595744680851, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI20336188, Length=422, Percent_Identity=27.2511848341232, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI299523015, Length=389, Percent_Identity=26.2210796915167, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI20336186, Length=391, Percent_Identity=27.3657289002558, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI20336246, Length=389, Percent_Identity=26.2210796915167, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983555, Length=362, Percent_Identity=26.5193370165746, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141268, Length=362, Percent_Identity=26.2430939226519, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320775, Length=218, Percent_Identity=33.9449541284404, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=194, Percent_Identity=33.5051546391753, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360987, Length=402, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642494, Length=402, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642490, Length=402, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45555723, Length=402, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642492, Length=402, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642488, Length=404, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642484, Length=404, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642486, Length=404, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 53852; Mature: 53721

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTSTAACP
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VTQAASTAAGETLVTRTVSHEAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQR
CHHHHHHHCCCHHHEEHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
VMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAALLALGQKMSADNAGALAQTFAADP
HHHHHCCCCCHHHHHHHHCCCCCCEEEEHHHCCCCEEEHHCCCCCCCCCCHHHHHHCCCC
DVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGINLPDAWNVTNGLPSVVTAVLDTGYR
CCEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCASAPSN
CCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCCC
SSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVA
CCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
GAPTNLTPAKVINLSLGGSGPCGDTFQQAINDVIARGTTVVVSAGNDGQATTLDRPANCK
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCC
GVISVGATDSTGQRAWYSNFGSDITLSAPGSNILSTSNAGTTVPTTDAYGTHSGTSLAAP
EEEEECCCCCCCCHHHHHCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
QVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVASATK
HHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEECCC
>Mature Secondary Structure 
SVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTSTAACP
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VTQAASTAAGETLVTRTVSHEAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQR
CHHHHHHHCCCHHHEEHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
VMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAALLALGQKMSADNAGALAQTFAADP
HHHHHCCCCCHHHHHHHHCCCCCCEEEEHHHCCCCEEEHHCCCCCCCCCCHHHHHHCCCC
DVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGINLPDAWNVTNGLPSVVTAVLDTGYR
CCEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCASAPSN
CCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCCC
SSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVA
CCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
GAPTNLTPAKVINLSLGGSGPCGDTFQQAINDVIARGTTVVVSAGNDGQATTLDRPANCK
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCC
GVISVGATDSTGQRAWYSNFGSDITLSAPGSNILSTSNAGTTVPTTDAYGTHSGTSLAAP
EEEEECCCCCCCCHHHHHCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
QVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVASATK
HHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]