BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

Click here to switch to the map view.

The map label for this gene is yxnA [H]

Identifier: 126446406

GI number: 126446406

Start: 2191381

End: 2192412

Strand: Reverse

Name: yxnA [H]

Synonym: BMA10247_A2259

Alternate gene names: 126446406

Gene position: 2192412-2191381 (Counterclockwise)

Preceding gene: 126447203

Following gene: 126446590

Centisome position: 93.19

GC content: 69.86

Gene sequence:

>1032_bases
ATGAAATGCACGCTGAAGCCGATCGGCGAGCAGACGATCGTGATCACCGGCGCGACGAGCGGCATCGGGCTCGTCACCGC
GCGCAAGGCCGCGAAGAAGGGCGCGAAGCTCGTGCTCGTCGCGCGCAACGATACCGCGCTCGAGGCGCTATGCGAGGAGA
TCCGCCAGCACGTCGGCCTCGCCGTCGCGGTCGCGGCCGACGTGAGCCGCTACGAGGACGTCCAGCGCGCGGCGGCGAAG
GCCGTCGAGACGTTCGGCGGCTTCGACACGTGGATCAACAACGCGGGCGTGACGATCTTCGGCTCCGCGCTGTCGGTGCC
GCTCGACGACCAGCGCCGGCTGTTCGATACGAACTACTGGGGCGTCGTGCATGGCTCGCTCGTCGCGTCCGAGCATTTTC
GCCGCAAGAGCGACTTTCGCGGCGGCGCGATCATCAACATGGGCAGCGAGGCGTCCGACGCGCCGGTGCCGCTGCAAAGC
GCGTATGCGGCATCCAAGCACGCGATCAAGGGCTTCACCGATTCGCTGCGCATCGAGCTCGAGGCGGACAACGTGCCGGT
GTCGGTCACGCTCGTCAAGCCCGCGGCCGTCGACACGATGTTCGTGATGCACGCGAAGAACTACATGAACGTCGAGGCGA
AGCTGCCGCCGCCGATCTACGATCCGGACATCGTCGCCGACGCGATCCTGTTCGCGGCCGAGCATGCCCGTCGCACGCTG
TTTGTCGGCGGCGCGGCGAAGCTCGCGTCGTCGGGCGCGTATCACGCGCCGCGGCTGTTCGACCGGCTCGCCACGTCGCT
GTTCTCGCGCGGGCAGCGCACGATGCGCCCCGCGCGGCCGCGCGACGACAACGCGCTGTACGAGCCGACGCGCCCGTTGC
ACGAGCGCGAAGGGATGGACGGCGTGGTGCTGCGCTCGTGCGCGTACAACACGGTGATGCAGCGGCCGAGAGTCGCCGGC
GCGCTCGCGCTGACGGCCGCGGCGCTCGTCGTCGCGGCGCTCGCGCGCGCTCGGCGCGACGTCGCTTCGTAG

Upstream 100 bases:

>100_bases
CGCCGTCGACGTGACCAGGCAGGTGGACGGCGTGAAGACCGTGCGCGACAAGCTGACGGTGCAGCCCAAGTAGCCGGCCC
GTTCGGCAAGGAGTCCAGTC

Downstream 100 bases:

>100_bases
CGCGTGCGGCGCGCTGCGCGCGAACGGCCCGCGATGCGGCGATGCGCATCCGCGCGGCTCGCGCCGCGTGGCGCGCCGCC
GTCCGCTTCCTGCGTTGCGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKCTLKPIGEQTIVITGATSGIGLVTARKAAKKGAKLVLVARNDTALEALCEEIRQHVGLAVAVAADVSRYEDVQRAAAK
AVETFGGFDTWINNAGVTIFGSALSVPLDDQRRLFDTNYWGVVHGSLVASEHFRRKSDFRGGAIINMGSEASDAPVPLQS
AYAASKHAIKGFTDSLRIELEADNVPVSVTLVKPAAVDTMFVMHAKNYMNVEAKLPPPIYDPDIVADAILFAAEHARRTL
FVGGAAKLASSGAYHAPRLFDRLATSLFSRGQRTMRPARPRDDNALYEPTRPLHEREGMDGVVLRSCAYNTVMQRPRVAG
ALALTAAALVVAALARARRDVAS

Sequences:

>Translated_343_residues
MKCTLKPIGEQTIVITGATSGIGLVTARKAAKKGAKLVLVARNDTALEALCEEIRQHVGLAVAVAADVSRYEDVQRAAAK
AVETFGGFDTWINNAGVTIFGSALSVPLDDQRRLFDTNYWGVVHGSLVASEHFRRKSDFRGGAIINMGSEASDAPVPLQS
AYAASKHAIKGFTDSLRIELEADNVPVSVTLVKPAAVDTMFVMHAKNYMNVEAKLPPPIYDPDIVADAILFAAEHARRTL
FVGGAAKLASSGAYHAPRLFDRLATSLFSRGQRTMRPARPRDDNALYEPTRPLHEREGMDGVVLRSCAYNTVMQRPRVAG
ALALTAAALVVAALARARRDVAS
>Mature_343_residues
MKCTLKPIGEQTIVITGATSGIGLVTARKAAKKGAKLVLVARNDTALEALCEEIRQHVGLAVAVAADVSRYEDVQRAAAK
AVETFGGFDTWINNAGVTIFGSALSVPLDDQRRLFDTNYWGVVHGSLVASEHFRRKSDFRGGAIINMGSEASDAPVPLQS
AYAASKHAIKGFTDSLRIELEADNVPVSVTLVKPAAVDTMFVMHAKNYMNVEAKLPPPIYDPDIVADAILFAAEHARRTL
FVGGAAKLASSGAYHAPRLFDRLATSLFSRGQRTMRPARPRDDNALYEPTRPLHEREGMDGVVLRSCAYNTVMQRPRVAG
ALALTAAALVVAALARARRDVAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=35.8208955223881, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=31.7708333333333, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=30.8900523560209, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI109715829, Length=227, Percent_Identity=27.7533039647577, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI7706318, Length=175, Percent_Identity=30.2857142857143, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI32483357, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4758504, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7657478, Length=313, Percent_Identity=27.4760383386581, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=32.6315789473684, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=200, Percent_Identity=32, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI142976729, Length=249, Percent_Identity=28.1124497991968, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI83715985, Length=169, Percent_Identity=34.9112426035503, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=33.1325301204819, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI32455239, Length=200, Percent_Identity=29.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=200, Percent_Identity=29.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557649, Length=207, Percent_Identity=31.4009661835749, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI40548397, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40254992, Length=226, Percent_Identity=26.9911504424779, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40807363, Length=247, Percent_Identity=25.5060728744939, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788459, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=191, Percent_Identity=30.8900523560209, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786701, Length=218, Percent_Identity=25.2293577981651, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=26.5625, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786812, Length=236, Percent_Identity=30.0847457627119, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=194, Percent_Identity=29.3814432989691, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=228, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=223, Percent_Identity=29.1479820627803, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=282, Percent_Identity=26.9503546099291, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=194, Percent_Identity=27.319587628866, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=28.2828282828283, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.615969581749, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=175, Percent_Identity=26.8571428571429, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=24.9027237354086, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=279, Percent_Identity=26.1648745519713, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=278, Percent_Identity=28.4172661870504, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=31.8367346938775, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319635, Length=194, Percent_Identity=30.4123711340206, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=205, Percent_Identity=31.219512195122, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356301, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007236, Length=225, Percent_Identity=31.1111111111111, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571387, Length=233, Percent_Identity=30.4721030042918, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=32.9896907216495, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648944, Length=222, Percent_Identity=31.0810810810811, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=183, Percent_Identity=31.1475409836066, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364494, Length=227, Percent_Identity=29.5154185022026, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=32.4742268041237, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641388, Length=203, Percent_Identity=30.0492610837438, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=30.7291666666667, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=28.4552845528455, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=26.6009852216749, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=32.2751322751323, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007238, Length=207, Percent_Identity=30.9178743961353, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=32.2751322751323, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649181, Length=273, Percent_Identity=25.2747252747253, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584752, Length=205, Percent_Identity=30.2439024390244, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355631, Length=180, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36823; Mature: 36823

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCTLKPIGEQTIVITGATSGIGLVTARKAAKKGAKLVLVARNDTALEALCEEIRQHVGL
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCE
AVAVAADVSRYEDVQRAAAKAVETFGGFDTWINNAGVTIFGSALSVPLDDQRRLFDTNYW
EEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECEEECCCCCCHHHHCCCCC
GVVHGSLVASEHFRRKSDFRGGAIINMGSEASDAPVPLQSAYAASKHAIKGFTDSLRIEL
EEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
EADNVPVSVTLVKPAAVDTMFVMHAKNYMNVEAKLPPPIYDPDIVADAILFAAEHARRTL
EECCCCEEEEEECCHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCEEE
FVGGAAKLASSGAYHAPRLFDRLATSLFSRGQRTMRPARPRDDNALYEPTRPLHEREGMD
EECCHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
GVVLRSCAYNTVMQRPRVAGALALTAAALVVAALARARRDVAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCTLKPIGEQTIVITGATSGIGLVTARKAAKKGAKLVLVARNDTALEALCEEIRQHVGL
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCE
AVAVAADVSRYEDVQRAAAKAVETFGGFDTWINNAGVTIFGSALSVPLDDQRRLFDTNYW
EEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECEEECCCCCCHHHHCCCCC
GVVHGSLVASEHFRRKSDFRGGAIINMGSEASDAPVPLQSAYAASKHAIKGFTDSLRIEL
EEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
EADNVPVSVTLVKPAAVDTMFVMHAKNYMNVEAKLPPPIYDPDIVADAILFAAEHARRTL
EECCCCEEEEEECCHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCEEE
FVGGAAKLASSGAYHAPRLFDRLATSLFSRGQRTMRPARPRDDNALYEPTRPLHEREGMD
EECCHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
GVVLRSCAYNTVMQRPRVAGALALTAAALVVAALARARRDVAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]