Click here to switch to the map view.

The map label for this gene is ribA [H]

Identifier: 126446339

GI number: 126446339

Start: 908015

End: 908668

Strand: Direct

Name: ribA [H]

Synonym: BMA10247_A0959

Alternate gene names: 126446339

Gene position: 908015-908668 (Clockwise)

Preceding gene: 126447859

Following gene: 126445689

Centisome position: 38.59

GC content: 65.6

Gene sequence:

>654_bases
ATGAAGTCTTCGCATCCTGACTCGCCGCAGCCGGACGACGGCGCCGCGCCCGAGTGCGTGACGCTCGTCGCCACCGCGAC
GCTTCCTACCCGCTACGGCACGTTCACGTCGTATGCGTTTCGCGTGGCGGGCGGCGATGCCGAGCACCTCGCGCTCGTGA
TGGGCGACGTCGCCGAGCAGCCGTCGGTGCTGACGCGGCTTCATTCCGAGTGCCTGACGGGTGACGTGTTCGGCTCGTAT
CGATGCGATTGCGGCGAGCAGCTCGATCTCTCGCTGCGCTACATCGCGGCCGAAGGGCGCGGCGTATTGCTGTATCTGCG
CGGCCACGAAGGCCGCGGGATCGGCCTGAGCAACAAGATCCGCGCGTATGCGCTGCAGGAGCAGGGGCGCGACACCGTCG
AGGCGAACCTCGACCTCGGGCTACCCGACGACGCGCGCGAATACGATTCCGCCGCCGCGATCCTGCGCATCCTGAAAGTC
ACGTCCGTGCGACTGATGAGCAATAATCCGAAGAAGTTCGACACGCTCGCGCGGCACGGTATCCCGGTCTGCGAGCGCGT
CGCGCTCGCCGTGCCGGTGCGCGAGGAGAACGAGCGCTATATCCGCACGAAGCAGCTCAAGTTCGGCCACTATTATTTCG
ACGAAAACGAATAG

Upstream 100 bases:

>100_bases
TCGGCGTCCGCGGGCGGGTGCGTCCAGTGCGCAGATTAGCGGTAAACTCCGTGCACTCGCCATCCAAAACATACCTTAAT
CCTTTCGTTTGATGCATTCC

Downstream 100 bases:

>100_bases
CGCGCGTCGCGCGGCGCGGCTTGCGCGCGCCGAAGCGCTGCTCGGCGATCGGCAGATCGAAGCGGCAGCGCACTTCGGTC
GCGATCCAGTCGCAGGCCTG

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSY
RCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKV
TSVRLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE

Sequences:

>Translated_217_residues
MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSY
RCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKV
TSVRLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE
>Mature_217_residues
MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSY
RCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKV
TSVRLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=188, Percent_Identity=52.6595744680851, Blast_Score=187, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319438, Length=170, Percent_Identity=44.1176470588235, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 23963; Mature: 23963

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQ
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHEEEEECCCCHHHHHHEEHHHCCC
PSVLTRLHSECLTGDVFGSYRCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKI
CHHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCH
RAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKVTSVRLMSNNPKKFDTLARHG
HEEEEHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCC
IPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE
CCHHHHHEEECCCCCCCCCEEEEEEEEECEEEECCCC
>Mature Secondary Structure
MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQ
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHEEEEECCCCHHHHHHEEHHHCCC
PSVLTRLHSECLTGDVFGSYRCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKI
CHHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCH
RAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKVTSVRLMSNNPKKFDTLARHG
HEEEEHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCC
IPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE
CCHHHHHEEECCCCCCCCCEEEEEEEEECEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA