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The map label for this gene is nahR [H]

Identifier: 126446240

GI number: 126446240

Start: 2101013

End: 2101906

Strand: Direct

Name: nahR [H]

Synonym: BMA10247_A2167

Alternate gene names: 126446240

Gene position: 2101013-2101906 (Clockwise)

Preceding gene: 126446811

Following gene: 126446862

Centisome position: 89.3

GC content: 70.81

Gene sequence:

>894_bases
ATGGACAATCTCAGGCGGCTGGATCTGAACCTGCTGATCACGCTCGACGCGCTGCTGTCGGAGCACAACGTGACGCGCGC
GGCCGCACGGCTGAACCTGTCGCAACCGTCGGTCAGCATTCATCTCGCGAAGCTGAGGGACATCTTCGGCGATCCGCTGC
TGCTGCCGGGGCCGCGCGGCATGCGGCCCACCGCGCGCGCCGACGAATTGCGCGAGCCGCTGCGCCGCGCGCTCGAAACG
CTCGGGCGCGCGGTATCGCCGGGCGCGCCGTTCGATCCGGCCACCTCCGCTCACACGTGGCGCGTCGCCGCGTCCGACTA
CAGCGAATCGACGGTCGTGCTGCCCGCGCTGAACGGCCTGCGCGCGGCCGCGCCCGGCACGCGCCTGGCCGTCGTCGAAA
CCGTGCCGTCGCGCATCGCGAAGCAGGCCGAGCAAGGCGACATCGATCTCGCGTTCCACATCACCGAATGCGCGCCGGGC
AACCTGCGCCACCGCGCGCTCTTCACCGAGCGTTACGTGCTCGTCGGACGCGCCGGCCACCCCCGGCTGAAGCGGCGGCC
CACGCTCGCGCAGTTCTGCAAGCTCGACCACGTCATCGTCTCGCCGGACGGCGGCGGCTTTCAGGGCGGCACCGATCACG
CGCTCGCGAAGCTCGGCCTCGCGCGGCGCGTCGTGCTGTCCGTGCCGCACTTCCTGTTCATGATGTCGGCTGTCGCGAAC
AGCGATCTCGTTGCGATGATGCCGTCGCGGCTCGTGCGCGACAGCCGCGCGCTGCAAGTGGTCGAGCCGCCCGTCGACGT
GCCCGGCTTCCGGATGGCGATGCTCTGGCACGAGCGCTCGCATCGCGATCCCGCGCATCAGTGGCTGCGCGAGCATATCG
CGGCCTCGGTGTGA

Upstream 100 bases:

>100_bases
TTCATATCGGGAGAATCGATGGATTGACTGGAGAGGTGAACGCAGGTTATCGGCTGCTCGGGTATATTGGAAATTGATTT
CCAATATTCCAGGTATTGCA

Downstream 100 bases:

>100_bases
CGCGTTCGGTTCGGCATCGAACGCGCTTCGCCGCGCATGCGGGCCCATGCGTTCGCGCGACGTTCGAAGCGCCCGGACCG
TTCGGAAACCTATTTTTCAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MDNLRRLDLNLLITLDALLSEHNVTRAAARLNLSQPSVSIHLAKLRDIFGDPLLLPGPRGMRPTARADELREPLRRALET
LGRAVSPGAPFDPATSAHTWRVAASDYSESTVVLPALNGLRAAAPGTRLAVVETVPSRIAKQAEQGDIDLAFHITECAPG
NLRHRALFTERYVLVGRAGHPRLKRRPTLAQFCKLDHVIVSPDGGGFQGGTDHALAKLGLARRVVLSVPHFLFMMSAVAN
SDLVAMMPSRLVRDSRALQVVEPPVDVPGFRMAMLWHERSHRDPAHQWLREHIAASV

Sequences:

>Translated_297_residues
MDNLRRLDLNLLITLDALLSEHNVTRAAARLNLSQPSVSIHLAKLRDIFGDPLLLPGPRGMRPTARADELREPLRRALET
LGRAVSPGAPFDPATSAHTWRVAASDYSESTVVLPALNGLRAAAPGTRLAVVETVPSRIAKQAEQGDIDLAFHITECAPG
NLRHRALFTERYVLVGRAGHPRLKRRPTLAQFCKLDHVIVSPDGGGFQGGTDHALAKLGLARRVVLSVPHFLFMMSAVAN
SDLVAMMPSRLVRDSRALQVVEPPVDVPGFRMAMLWHERSHRDPAHQWLREHIAASV
>Mature_297_residues
MDNLRRLDLNLLITLDALLSEHNVTRAAARLNLSQPSVSIHLAKLRDIFGDPLLLPGPRGMRPTARADELREPLRRALET
LGRAVSPGAPFDPATSAHTWRVAASDYSESTVVLPALNGLRAAAPGTRLAVVETVPSRIAKQAEQGDIDLAFHITECAPG
NLRHRALFTERYVLVGRAGHPRLKRRPTLAQFCKLDHVIVSPDGGGFQGGTDHALAKLGLARRVVLSVPHFLFMMSAVAN
SDLVAMMPSRLVRDSRALQVVEPPVDVPGFRMAMLWHERSHRDPAHQWLREHIAASV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=29.042904290429, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081766, Length=286, Percent_Identity=27.972027972028, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32593; Mature: 32593

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLRRLDLNLLITLDALLSEHNVTRAAARLNLSQPSVSIHLAKLRDIFGDPLLLPGPRG
CCCCCEECHHHEEEHHHHHHHCCHHHHHHHCCCCCCCCEEHHHHHHHHHCCCEECCCCCC
MRPTARADELREPLRRALETLGRAVSPGAPFDPATSAHTWRVAASDYSESTVVLPALNGL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCC
RAAAPGTRLAVVETVPSRIAKQAEQGDIDLAFHITECAPGNLRHRALFTERYVLVGRAGH
CCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCEEEEECCCC
PRLKRRPTLAQFCKLDHVIVSPDGGGFQGGTDHALAKLGLARRVVLSVPHFLFMMSAVAN
CCCCCCCCHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDLVAMMPSRLVRDSRALQVVEPPVDVPGFRMAMLWHERSHRDPAHQWLREHIAASV
CCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNLRRLDLNLLITLDALLSEHNVTRAAARLNLSQPSVSIHLAKLRDIFGDPLLLPGPRG
CCCCCEECHHHEEEHHHHHHHCCHHHHHHHCCCCCCCCEEHHHHHHHHHCCCEECCCCCC
MRPTARADELREPLRRALETLGRAVSPGAPFDPATSAHTWRVAASDYSESTVVLPALNGL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCC
RAAAPGTRLAVVETVPSRIAKQAEQGDIDLAFHITECAPGNLRHRALFTERYVLVGRAGH
CCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCEEEEECCCC
PRLKRRPTLAQFCKLDHVIVSPDGGGFQGGTDHALAKLGLARRVVLSVPHFLFMMSAVAN
CCCCCCCCHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDLVAMMPSRLVRDSRALQVVEPPVDVPGFRMAMLWHERSHRDPAHQWLREHIAASV
CCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]