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The map label for this gene is yveA [H]

Identifier: 126446001

GI number: 126446001

Start: 831270

End: 833198

Strand: Reverse

Name: yveA [H]

Synonym: BMA10247_A0878

Alternate gene names: 126446001

Gene position: 833198-831270 (Counterclockwise)

Preceding gene: 126446547

Following gene: 126446089

Centisome position: 35.41

GC content: 71.02

Gene sequence:

>1929_bases
ATGCGCCCGCCGCCGATCGCCGCACGCGCCGCGTTGCGTGCGCGATGCGCGATGCGCGACGCCGCCGATCGGGCGCCGGC
CTTGCGTTTCGCGCGGAGGCGATGCCGCGCGAAACCGCCGCGACGGCTCGCCCGCGCGCCGCAGCACGATTCGGCTGAAT
CGGCCGGGCGCGCCGCCGCGGATCGGCGCGCGCCTCGCCGTCGCACGGGCCGCCCCGCCCGCCGCCACGCAAGCGCGGCT
GTAACGGCCGAGGCGGCCGCGGCGGGCGCGCCGTCAGCTCCGCCCGCCGCGGCCCTCCCATGCGCCGCCGCGCCCCGCCC
GCCGCTCGAGACGATCGAAACCCGTCCATCAAATCAAGGAGACAAGCCCATGCCCGCCCAAGGCAATGCCCAGCGAACCG
CGCCGCTCGCGCGGCCCGCGCCCACCGACGCCGGCCACGGCAAGTTCAAGAAACAGCTGTCGCTCACCGATCTGACGTTC
ATCGGCCTCGGCGCGATCTTCGGCTCGGGGTGGCTGTTCGCCGCGAGCCACGTATCGACGATCGCGGGCCCGGCCGGCAT
CCTCTCGTGGCTGCTCGGCGGCTTCGCGGTGCTGCTGCTCGGCATCGTCTACTGCGAGCTCGGCGCGGCGCTGCCGCGCG
CGGGCGGCGTCGTCCGCTATCCGGTGTTCTCGCACGGCCCGCTGCTCGGCTACCTGATGGGCGCGATCACGCTGATCGCG
TTCTCGAGCCTGATCGCGATCGAAGTCGTCGCCGCGCGCCAGTATGCGGCCGCGTGGTTTGCGGGCCTGACCGTCGAGGG
CTCGGGCAATCCGACGACGCTCGGCTGGCTCGTGCAGGCGGCGCTGCTCTGTTTCTTCTTCTACCTGAACTATTCGAGCG
TGAAGACGTTCGCGAAGGCGAACAACGTCATCAGCGTGTTCAAGTTCGTCGTGCCGCTCGCGGTGATCGTCGTGCTGTTC
GCGTTCTTCAAGCCCGCGAACCTCACCCTGCACGGCTTCGCGCCGTTCGGCATGCCCGGCGTCGAGATGGCCGTGTCCGC
GGGCGGCATCATCTTCGCGTATCTCGGCCTCACGCCGATCGTCTCGGTCGCGAGCGAGGTGCGCGACCCGCAGCGCACGA
TTCCGATCGCGCTGATCCTGTCGATCGTGCTCTCGACGCTGATCTACGTGCTGCTGCAGCTCGCGTTCCTCGGCGGCATC
CCGAGCGCGATGCTCGCGGGCGGCTGGCTCGCGTACATGGTCGTCGCCGACGCGATGATCTCGCCGTCCGGCTGCGGCAA
TATCTACATGAACGCGACGCCGCGCGTCGTCTACGGCTGGGCGAAGACGGGCACGTTCTTCAAGGTGTTCGCGCGCGTCG
ACGAGGCCTCCGGCATTCCGCGCGCGGGGCTGTGGCTCACGTTCGCGCTGGCGCTCTTCTGGACGCTGCCTTTCCCGTCG
TGGGAGGCGCTCATCAACACCGTGTCGGCCGCGCTCGTGCTGAGCTACGCGGTCGCGCCGGTATCGGTCGCCGCGCTGCG
CCGCACCGCGCCCGGGCTGCCGCGGCCGTTTCGCGCGAGCGCGTTCGCGCTCACCGGCCCCGCTTCGTTCGTGATCGCCG
CGCTGATCGTCTACTGGTCCGGCTGGCGCACCGTGTCGTGGCTGCTCGGGCTGCAGATCGCGATGTTCGCCGTCTATCTC
GCGTGCCGCCGCCGGGTGCCCACCGCGCATCTGAGCCTCGCCGAGCAGGTGCGCTCGTGCGCGTGGCTGATCGCGTTCTA
CGCGCTGATGATCGTCGCGTCGTATTTCGGCGGCTTCGGCGGCACCGGGCAGCTCGCGCACCCGTACGACACGTTCGCCG
TCGCGGCCGTCGCGCTCGTCATCTACTACTGGGGCGCGCATACCGGCGTGCCGTCCGCGAAGCTGCAGCTCGACGACGAC
GAGAACTGA

Upstream 100 bases:

>100_bases
GGCCTTTGAGCGACGCGGATGCGGCGCGCGGCGGGGATTCCGGCGCCGGCTTGAGCCCCGCCCCGGCTCGGGCGACGTGC
GCGGCGCGGAACGCGCCGTC

Downstream 100 bases:

>100_bases
CGCGCGGCGCGGGCGCATCCGCTTTTTCAACGGCCGCGCGGCGACGCGCGGCCCGCACTTTCTGCGAGGAGAACCATGCG
ACTCACTGGCGAGCTTTTGA

Product: amino acid permease

Products: Proton [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: L-aspartate transporter [H]

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MRPPPIAARAALRARCAMRDAADRAPALRFARRRCRAKPPRRLARAPQHDSAESAGRAAADRRAPRRRTGRPARRHASAA
VTAEAAAAGAPSAPPAAALPCAAAPRPPLETIETRPSNQGDKPMPAQGNAQRTAPLARPAPTDAGHGKFKKQLSLTDLTF
IGLGAIFGSGWLFAASHVSTIAGPAGILSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGAITLIA
FSSLIAIEVVAARQYAAAWFAGLTVEGSGNPTTLGWLVQAALLCFFFYLNYSSVKTFAKANNVISVFKFVVPLAVIVVLF
AFFKPANLTLHGFAPFGMPGVEMAVSAGGIIFAYLGLTPIVSVASEVRDPQRTIPIALILSIVLSTLIYVLLQLAFLGGI
PSAMLAGGWLAYMVVADAMISPSGCGNIYMNATPRVVYGWAKTGTFFKVFARVDEASGIPRAGLWLTFALALFWTLPFPS
WEALINTVSAALVLSYAVAPVSVAALRRTAPGLPRPFRASAFALTGPASFVIAALIVYWSGWRTVSWLLGLQIAMFAVYL
ACRRRVPTAHLSLAEQVRSCAWLIAFYALMIVASYFGGFGGTGQLAHPYDTFAVAAVALVIYYWGAHTGVPSAKLQLDDD
EN

Sequences:

>Translated_642_residues
MRPPPIAARAALRARCAMRDAADRAPALRFARRRCRAKPPRRLARAPQHDSAESAGRAAADRRAPRRRTGRPARRHASAA
VTAEAAAAGAPSAPPAAALPCAAAPRPPLETIETRPSNQGDKPMPAQGNAQRTAPLARPAPTDAGHGKFKKQLSLTDLTF
IGLGAIFGSGWLFAASHVSTIAGPAGILSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGAITLIA
FSSLIAIEVVAARQYAAAWFAGLTVEGSGNPTTLGWLVQAALLCFFFYLNYSSVKTFAKANNVISVFKFVVPLAVIVVLF
AFFKPANLTLHGFAPFGMPGVEMAVSAGGIIFAYLGLTPIVSVASEVRDPQRTIPIALILSIVLSTLIYVLLQLAFLGGI
PSAMLAGGWLAYMVVADAMISPSGCGNIYMNATPRVVYGWAKTGTFFKVFARVDEASGIPRAGLWLTFALALFWTLPFPS
WEALINTVSAALVLSYAVAPVSVAALRRTAPGLPRPFRASAFALTGPASFVIAALIVYWSGWRTVSWLLGLQIAMFAVYL
ACRRRVPTAHLSLAEQVRSCAWLIAFYALMIVASYFGGFGGTGQLAHPYDTFAVAAVALVIYYWGAHTGVPSAKLQLDDD
EN
>Mature_642_residues
MRPPPIAARAALRARCAMRDAADRAPALRFARRRCRAKPPRRLARAPQHDSAESAGRAAADRRAPRRRTGRPARRHASAA
VTAEAAAAGAPSAPPAAALPCAAAPRPPLETIETRPSNQGDKPMPAQGNAQRTAPLARPAPTDAGHGKFKKQLSLTDLTF
IGLGAIFGSGWLFAASHVSTIAGPAGILSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGAITLIA
FSSLIAIEVVAARQYAAAWFAGLTVEGSGNPTTLGWLVQAALLCFFFYLNYSSVKTFAKANNVISVFKFVVPLAVIVVLF
AFFKPANLTLHGFAPFGMPGVEMAVSAGGIIFAYLGLTPIVSVASEVRDPQRTIPIALILSIVLSTLIYVLLQLAFLGGI
PSAMLAGGWLAYMVVADAMISPSGCGNIYMNATPRVVYGWAKTGTFFKVFARVDEASGIPRAGLWLTFALALFWTLPFPS
WEALINTVSAALVLSYAVAPVSVAALRRTAPGLPRPFRASAFALTGPASFVIAALIVYWSGWRTVSWLLGLQIAMFAVYL
ACRRRVPTAHLSLAEQVRSCAWLIAFYALMIVASYFGGFGGTGQLAHPYDTFAVAAVALVIYYWGAHTGVPSAKLQLDDD
EN

Specific function: Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI258614003, Length=431, Percent_Identity=24.3619489559165, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI258614005, Length=431, Percent_Identity=24.3619489559165, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI110347453, Length=404, Percent_Identity=26.4851485148515, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI258645169, Length=431, Percent_Identity=23.6658932714617, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI33286428, Length=436, Percent_Identity=24.5412844036697, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI187423910, Length=423, Percent_Identity=22.6950354609929, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI7657591, Length=423, Percent_Identity=22.6950354609929, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI115648063, Length=476, Percent_Identity=21.8487394957983, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI115648022, Length=476, Percent_Identity=21.8487394957983, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI181337167, Length=392, Percent_Identity=23.7244897959184, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1788480, Length=360, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87082250, Length=351, Percent_Identity=27.0655270655271, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081708, Length=255, Percent_Identity=25.0980392156863, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=409, Percent_Identity=26.8948655256724, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17533459, Length=424, Percent_Identity=26.4150943396226, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=404, Percent_Identity=23.7623762376238, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17568033, Length=424, Percent_Identity=24.0566037735849, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667468, Length=399, Percent_Identity=24.3107769423559, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21357367, Length=458, Percent_Identity=26.8558951965066, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=25.531914893617, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=25.531914893617, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550968, Length=469, Percent_Identity=26.0127931769723, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19921172, Length=469, Percent_Identity=26.0127931769723, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668806, Length=425, Percent_Identity=23.2941176470588, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356285, Length=425, Percent_Identity=23.2941176470588, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24668802, Length=425, Percent_Identity=23.2941176470588, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331183, Length=281, Percent_Identity=28.1138790035587, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17647653, Length=281, Percent_Identity=28.1138790035587, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24664379, Length=281, Percent_Identity=28.1138790035587, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641995, Length=416, Percent_Identity=24.5192307692308, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641993, Length=416, Percent_Identity=24.5192307692308, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 68024; Mature: 68024

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPPIAARAALRARCAMRDAADRAPALRFARRRCRAKPPRRLARAPQHDSAESAGRAAA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHH
DRRAPRRRTGRPARRHASAAVTAEAAAAGAPSAPPAAALPCAAAPRPPLETIETRPSNQG
HHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
DKPMPAQGNAQRTAPLARPAPTDAGHGKFKKQLSLTDLTFIGLGAIFGSGWLFAASHVST
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAGPAGILSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGAITLIA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
FSSLIAIEVVAARQYAAAWFAGLTVEGSGNPTTLGWLVQAALLCFFFYLNYSSVKTFAKA
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNVISVFKFVVPLAVIVVLFAFFKPANLTLHGFAPFGMPGVEMAVSAGGIIFAYLGLTPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHH
VSVASEVRDPQRTIPIALILSIVLSTLIYVLLQLAFLGGIPSAMLAGGWLAYMVVADAMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SPSGCGNIYMNATPRVVYGWAKTGTFFKVFARVDEASGIPRAGLWLTFALALFWTLPFPS
CCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
WEALINTVSAALVLSYAVAPVSVAALRRTAPGLPRPFRASAFALTGPASFVIAALIVYWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHC
GWRTVSWLLGLQIAMFAVYLACRRRVPTAHLSLAEQVRSCAWLIAFYALMIVASYFGGFG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTGQLAHPYDTFAVAAVALVIYYWGAHTGVPSAKLQLDDDEN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MRPPPIAARAALRARCAMRDAADRAPALRFARRRCRAKPPRRLARAPQHDSAESAGRAAA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHH
DRRAPRRRTGRPARRHASAAVTAEAAAAGAPSAPPAAALPCAAAPRPPLETIETRPSNQG
HHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
DKPMPAQGNAQRTAPLARPAPTDAGHGKFKKQLSLTDLTFIGLGAIFGSGWLFAASHVST
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAGPAGILSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGAITLIA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
FSSLIAIEVVAARQYAAAWFAGLTVEGSGNPTTLGWLVQAALLCFFFYLNYSSVKTFAKA
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNVISVFKFVVPLAVIVVLFAFFKPANLTLHGFAPFGMPGVEMAVSAGGIIFAYLGLTPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHH
VSVASEVRDPQRTIPIALILSIVLSTLIYVLLQLAFLGGIPSAMLAGGWLAYMVVADAMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SPSGCGNIYMNATPRVVYGWAKTGTFFKVFARVDEASGIPRAGLWLTFALALFWTLPFPS
CCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
WEALINTVSAALVLSYAVAPVSVAALRRTAPGLPRPFRASAFALTGPASFVIAALIVYWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHC
GWRTVSWLLGLQIAMFAVYLACRRRVPTAHLSLAEQVRSCAWLIAFYALMIVASYFGGFG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTGQLAHPYDTFAVAAVALVIYYWGAHTGVPSAKLQLDDDEN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-lysine [Periplasm] = Proton [Cytoplasm] + L-lysine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]