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The map label for this gene is stcD [H]

Identifier: 126445991

GI number: 126445991

Start: 1902020

End: 1904083

Strand: Reverse

Name: stcD [H]

Synonym: BMA10247_A1976

Alternate gene names: 126445991

Gene position: 1904083-1902020 (Counterclockwise)

Preceding gene: 126446458

Following gene: 126447501

Centisome position: 80.93

GC content: 67.2

Gene sequence:

>2064_bases
ATGCGTTATCCCCACCTGTTCAAACCCCTGCAGCTGAACCAGCTGACGCTGCGCAACCGGATCGTCAGCACCGCGCACGC
GGAGGTGTACGCGGAGCCGGGCGGCCTGCCGGGCGAGCGCTACATCCGTTACTACGAAGAGAAGGCGAAGGGCGGCGTCG
GCCTCGCCGTGTGCGGCGGATCGAGCCCCGTGTCGATCGACAGCCCGCAGGGCTGGTGGAAATCGGTGAACCTGTCGACC
GACAAGATCGTCGATCCGCTTGCGCGGCTCGCCGAGGCGATGCACCGGCACGGCGCGAAGATCATGATCCAGGCGACGCA
CATGGGCCGCCGCTCGGCGTTTCACGGCGAGCACTGGCCGCACCTGATGTCGCCGTCGGGCGTGCGCGAGCCGGTGCACC
GCGGTAACGCGAAGATCATCGAGGTCGAGGAGATCCGGCGGATCATCGGCGATTTCGCGGCCGCCGCGAAGCGCGTGAAG
GACGCGGGCATGGACGGCATCGAGATCTCGGCCGCGCACCAGCATCTGATCGACCAGTTCTGGAGCCCGCGCACGAACGT
GCGCACCGACGAATGGGGCGGCAGCCTCGAGAACCGGCTGCGCTTCGGCGTCGAAGTGCTGACGGCGGTGCGCGAGGCGG
TGGGGCGCGACTTCTGCGTCGGCCTGCGGATGTGCGGCGACGAATTTCACGAGGACGGCCTCGATCACGAGCAGTTGAAG
GAGATCGCGCAGGCGATGTCCGAGACGGGCCTGATCGATTATCTCGGCGTGATCGGCTCCGGCGCGGACACGCACAACAC
GCTCGCGAACTGCATGCCGCCGATGGCGCTGCCGCCCGAGCCGTTCGTGCATCTCGCGGCGGGCATCAAGTCCGTCGTCA
GGATTCCGGTGATGCACGCGCAAAGCATTCGCGACGCGGGCCAGGCCGAGCGCCTGCTCGCGAACGGGATGATCGACCTC
GTCGGCATGACGCGCGCGCAGATCGCCGATCCGCACATGGTGATCAAGATCCGCGATGGCCGCGAGGACGAGATCAAGCA
GTGCGTCGGCGCGAACTACTGCATCGATCGCCAGTACAACGGCCTCGACGTGCTGTGCGTGCAGAACGCGGCGACTTCGC
GCGAGGCGACGATGCCGCACGTGATCGAGAAGTCGCGCGGGCCGAAACGCAAGGTCGTCGTGGTCGGCGCGGGCCCGGCG
GGCCTGGAGGCCGCGCGCGTCGCCCGCTCGCGCGGGCACGACGTCGTGCTGTTCGAGAAGAACGCCGAAGTCGGCGGGCA
GATCATGCTCGCGGCGAAGGCGCCGCAGCGCGAGCAGATGGCGGGCATCGTGCGCTGGTTCGACATGGAGACGAAGCGGC
TCGGCGTCGACCGCCGGCTCGGCGTCGAGGCCGACGAGAAGGCAATCATGGCCGAGAAGCCGGACATCATCGTGCTCGCC
ACGGGCGGGCGCAGCTTCACCGATCAGGTGTCGGGCTGGGGCGTCGCCGAGGGGCACGCGGTCGGCTCGTGGGACATCCT
GTCGGGCCGCGTCGAGCCGGGAAAGAACGTGCTCGTCTATGACGGCGTCAGCACGCATGCGGGCGCGGGCGTCGCGGATT
TCATCGCGAGCCGCGGCTCGAACGTGGAGATCGTCACGCCGGACGTGAAGGTGGCCGACGACTGCGGCGGCACGACGTTC
CCGATTTTCTATCGGCGGCTCTACGCGCAGGGCGTGATCCACACGCCGAACTACTGGCTCGACCGCGTCTACGAGGAAGA
CGGCAAAAAGATCGCGGTGCTGCGCAACGAATACACGGAAGAGCAGGAGGAGCGCGCGGTCGATCAGGTCGTGATCGAGA
ACGGCATCACGCCGAATGATGCGCTGTACTGGAAGCTCAAGCCCGAATCGGTCAATCGCGGCCAGATCGACGTGCACAAA
CTATTCGCCGCCGAGCCGCAGCCGTGCCTTGCCGAGACGCTCGGCAACGGCCGCTTCCTGCTGTTTCGCGTCGGCGATTG
CATCTCGATGCACAACATCCACGGCGCGATCTATGACGCGCTGCGCCTCGTGAAGGATTTCTGA

Upstream 100 bases:

>100_bases
TGACCATTGCGTCTTCGAAGTGTCGCCGATCGCGCGCTGATCCGCCGACGCCGAACCCCACTCGCAACACCCGATATTCG
AACGCCAGAGGTCGCCTGCG

Downstream 100 bases:

>100_bases
CGATGAATCCGGCCATCCTGATTACCGCGCTGCTGTGGCTGTCGGTCGCGGGCCTCGCGTTCGCGGTCGCGAAACGCTCG
GCGTACTGGCGGCTCGGCCG

Product: oxidoreductase, FAD/FMN-binding

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: Stachydrine utilization protein stcD [H]

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MRYPHLFKPLQLNQLTLRNRIVSTAHAEVYAEPGGLPGERYIRYYEEKAKGGVGLAVCGGSSPVSIDSPQGWWKSVNLST
DKIVDPLARLAEAMHRHGAKIMIQATHMGRRSAFHGEHWPHLMSPSGVREPVHRGNAKIIEVEEIRRIIGDFAAAAKRVK
DAGMDGIEISAAHQHLIDQFWSPRTNVRTDEWGGSLENRLRFGVEVLTAVREAVGRDFCVGLRMCGDEFHEDGLDHEQLK
EIAQAMSETGLIDYLGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVVRIPVMHAQSIRDAGQAERLLANGMIDL
VGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYNGLDVLCVQNAATSREATMPHVIEKSRGPKRKVVVVGAGPA
GLEAARVARSRGHDVVLFEKNAEVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVEADEKAIMAEKPDIIVLA
TGGRSFTDQVSGWGVAEGHAVGSWDILSGRVEPGKNVLVYDGVSTHAGAGVADFIASRGSNVEIVTPDVKVADDCGGTTF
PIFYRRLYAQGVIHTPNYWLDRVYEEDGKKIAVLRNEYTEEQEERAVDQVVIENGITPNDALYWKLKPESVNRGQIDVHK
LFAAEPQPCLAETLGNGRFLLFRVGDCISMHNIHGAIYDALRLVKDF

Sequences:

>Translated_687_residues
MRYPHLFKPLQLNQLTLRNRIVSTAHAEVYAEPGGLPGERYIRYYEEKAKGGVGLAVCGGSSPVSIDSPQGWWKSVNLST
DKIVDPLARLAEAMHRHGAKIMIQATHMGRRSAFHGEHWPHLMSPSGVREPVHRGNAKIIEVEEIRRIIGDFAAAAKRVK
DAGMDGIEISAAHQHLIDQFWSPRTNVRTDEWGGSLENRLRFGVEVLTAVREAVGRDFCVGLRMCGDEFHEDGLDHEQLK
EIAQAMSETGLIDYLGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVVRIPVMHAQSIRDAGQAERLLANGMIDL
VGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYNGLDVLCVQNAATSREATMPHVIEKSRGPKRKVVVVGAGPA
GLEAARVARSRGHDVVLFEKNAEVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVEADEKAIMAEKPDIIVLA
TGGRSFTDQVSGWGVAEGHAVGSWDILSGRVEPGKNVLVYDGVSTHAGAGVADFIASRGSNVEIVTPDVKVADDCGGTTF
PIFYRRLYAQGVIHTPNYWLDRVYEEDGKKIAVLRNEYTEEQEERAVDQVVIENGITPNDALYWKLKPESVNRGQIDVHK
LFAAEPQPCLAETLGNGRFLLFRVGDCISMHNIHGAIYDALRLVKDF
>Mature_687_residues
MRYPHLFKPLQLNQLTLRNRIVSTAHAEVYAEPGGLPGERYIRYYEEKAKGGVGLAVCGGSSPVSIDSPQGWWKSVNLST
DKIVDPLARLAEAMHRHGAKIMIQATHMGRRSAFHGEHWPHLMSPSGVREPVHRGNAKIIEVEEIRRIIGDFAAAAKRVK
DAGMDGIEISAAHQHLIDQFWSPRTNVRTDEWGGSLENRLRFGVEVLTAVREAVGRDFCVGLRMCGDEFHEDGLDHEQLK
EIAQAMSETGLIDYLGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVVRIPVMHAQSIRDAGQAERLLANGMIDL
VGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYNGLDVLCVQNAATSREATMPHVIEKSRGPKRKVVVVGAGPA
GLEAARVARSRGHDVVLFEKNAEVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVEADEKAIMAEKPDIIVLA
TGGRSFTDQVSGWGVAEGHAVGSWDILSGRVEPGKNVLVYDGVSTHAGAGVADFIASRGSNVEIVTPDVKVADDCGGTTF
PIFYRRLYAQGVIHTPNYWLDRVYEEDGKKIAVLRNEYTEEQEERAVDQVVIENGITPNDALYWKLKPESVNRGQIDVHK
LFAAEPQPCLAETLGNGRFLLFRVGDCISMHNIHGAIYDALRLVKDF

Specific function: Possible NADH-dependent oxidase, functions as a demethylase that converts N-methylproline to proline [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=669, Percent_Identity=30.7922272047833, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI1787939, Length=359, Percent_Identity=26.1838440111421, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=243, Percent_Identity=31.2757201646091, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=344, Percent_Identity=23.546511627907, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=377, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=346, Percent_Identity=27.7456647398844, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=336, Percent_Identity=25.297619047619, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=370, Percent_Identity=27.027027027027, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI72001454, Length=350, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=242, Percent_Identity=29.3388429752066, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325086, Length=246, Percent_Identity=28.4552845528455, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 75585; Mature: 75585

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYPHLFKPLQLNQLTLRNRIVSTAHAEVYAEPGGLPGERYIRYYEEKAKGGVGLAVCGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECC
SSPVSIDSPQGWWKSVNLSTDKIVDPLARLAEAMHRHGAKIMIQATHMGRRSAFHGEHWP
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
HLMSPSGVREPVHRGNAKIIEVEEIRRIIGDFAAAAKRVKDAGMDGIEISAAHQHLIDQF
CCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
WSPRTNVRTDEWGGSLENRLRFGVEVLTAVREAVGRDFCVGLRMCGDEFHEDGLDHEQLK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
EIAQAMSETGLIDYLGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVVRIPVMHA
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QSIRDAGQAERLLANGMIDLVGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYN
HHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEECCCCC
GLDVLCVQNAATSREATMPHVIEKSRGPKRKVVVVGAGPAGLEAARVARSRGHDVVLFEK
CEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEC
NAEVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVEADEKAIMAEKPDIIVLA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHEECCCCEEEEE
TGGRSFTDQVSGWGVAEGHAVGSWDILSGRVEPGKNVLVYDGVSTHAGAGVADFIASRGS
CCCCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCC
NVEIVTPDVKVADDCGGTTFPIFYRRLYAQGVIHTPNYWLDRVYEEDGKKIAVLRNEYTE
CEEEECCCCEEECCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHCCCEEEEEHHHHHH
EQEERAVDQVVIENGITPNDALYWKLKPESVNRGQIDVHKLFAAEPQPCLAETLGNGRFL
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCHHHHHHCCCCCEE
LFRVGDCISMHNIHGAIYDALRLVKDF
EEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYPHLFKPLQLNQLTLRNRIVSTAHAEVYAEPGGLPGERYIRYYEEKAKGGVGLAVCGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECC
SSPVSIDSPQGWWKSVNLSTDKIVDPLARLAEAMHRHGAKIMIQATHMGRRSAFHGEHWP
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
HLMSPSGVREPVHRGNAKIIEVEEIRRIIGDFAAAAKRVKDAGMDGIEISAAHQHLIDQF
CCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
WSPRTNVRTDEWGGSLENRLRFGVEVLTAVREAVGRDFCVGLRMCGDEFHEDGLDHEQLK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
EIAQAMSETGLIDYLGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVVRIPVMHA
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QSIRDAGQAERLLANGMIDLVGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYN
HHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEECCCCC
GLDVLCVQNAATSREATMPHVIEKSRGPKRKVVVVGAGPAGLEAARVARSRGHDVVLFEK
CEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEC
NAEVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVEADEKAIMAEKPDIIVLA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHEECCCCEEEEE
TGGRSFTDQVSGWGVAEGHAVGSWDILSGRVEPGKNVLVYDGVSTHAGAGVADFIASRGS
CCCCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCC
NVEIVTPDVKVADDCGGTTFPIFYRRLYAQGVIHTPNYWLDRVYEEDGKKIAVLRNEYTE
CEEEECCCCEEECCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHCCCEEEEEHHHHHH
EQEERAVDQVVIENGITPNDALYWKLKPESVNRGQIDVHKLFAAEPQPCLAETLGNGRFL
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCHHHHHHCCCCCEE
LFRVGDCISMHNIHGAIYDALRLVKDF
EEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9758825; 11481431 [H]