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The map label for this gene is phnW

Identifier: 126445601

GI number: 126445601

Start: 847695

End: 848804

Strand: Reverse

Name: phnW

Synonym: BMA10247_A0895

Alternate gene names: 126445601

Gene position: 848804-847695 (Counterclockwise)

Preceding gene: 126447757

Following gene: 126446546

Centisome position: 36.08

GC content: 72.61

Gene sequence:

>1110_bases
ATGCCAGAACGTGATCCCATCCTGTTGACGCCCGGCCCGCTGACGACCTCGCGCATGACGCGCGACGCGATGCTGCGCGA
CTGGGGCTCGTGGGACGCCGCTTTCAACCGGCTGACGAAGAGCGTCTGCGCGGATCTCGTGCGGATCGCGGGCGGCGGCG
ACGCATATGTGTGCGTGCCGCTGCAAGGCAGCGGCACGTTTGCGGTCGAAGCGACGCTCGGCACGCTCGTGCCGCGCGAC
GCCCGCGTGCTCGTGCCGAACAACGGCGCGTACTGCGCGCGGATCGCGGCGATCCTGCGCCGGCTCGGCATCGCGCACGT
CGAGCTGCCGTTCGCCGAGGACGAGCCGGCGAGCGCGCACGCGATCGACGCGGCGCTCGCGCGCGACGCGCGCCTCACGC
ACGTCGCGCTCGTGCATCTGGAGACGAGCGCCGGCCTGCTGAACCCGCTCGACGACATCGCCGCCGTCTGCCGCGCGCGC
GGCAGGGCGCTGATCGTCGACGCGATGAGCTCGTTCGGCGCGCTGCCGATCGCGCTCGCGGCAAGCGGCATCGACGCGCT
GATCTCGGCGAGCGGCAAGTGCCTGGAAGGAGTGCCCGGCATGGGCTTCGCGATCGTGCGGCGTTCGGCGCTCGAAGCGG
CCGAGGGGCGCTCGCCGTCGGTCGCGCTCGATCTGCACGACCAGTACGCATACATGCAGCGCACGTCGCAATGGCGCTTC
ACGCCGCCGACGCACGTGCTCGCCGCGCTGCGCGCCGCGCTCGACCAGTTCTTCGACGAAGGCGGGCAGCCGGCGCGCGG
CGCGCGCTACGCGCGGAACTGCGCGACGCTCGTCGACGGCATGCGCGCGCTCGGCTTCGAGCCGTTTCTCGACGCGCGCG
CGCAGGCGAGCGTGATCGTCACGTTCTACGCGCCCGCCGATCCCGCGTATGCGTTCCCGGCGTTCTACGCGGCCGTGCGC
GACGCGGGCTACGTGCTGTATCCGGGCAAGCTGACGACGGCCGACACGTTTCGCGTCGGCTGCATCGGCGCGCTCGGCGC
CGACGAGATGCGCGGCGCGGTGGCGGCGATCGGCGGCGCGCTCGAATCGCTCGGAATCGCGATGCGGTGA

Upstream 100 bases:

>100_bases
TCCGTGACGATTGACTTCATTTCCAAAAAACGACACATTTCGCCACTATCCTCCACATCCATCGACCACTGTTCCCGATC
TTTTCCGGAGTGACGAAGCC

Downstream 100 bases:

>100_bases
CGGGGAAGCAGTGAAGTCGCAAAGGGAAAGCGTGGGCCGCGGCGCGAAGGCGGGAACGACAAGTCGAGCGTTGCGGGCCA
CGCCCTGCCGTTATCGGGTG

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRD
ARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRAR
GRALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVR
DAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR

Sequences:

>Translated_369_residues
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRD
ARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRAR
GRALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVR
DAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
>Mature_368_residues
PERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDA
RVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARG
RALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFT
PPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRD
AGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=307, Percent_Identity=26.7100977198697, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536281, Length=306, Percent_Identity=24.1830065359477, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_BURM7 (A3MCV7)

Other databases:

- EMBL:   CP000547
- RefSeq:   YP_001078093.1
- ProteinModelPortal:   A3MCV7
- SMR:   A3MCV7
- GeneID:   4889953
- GenomeReviews:   CP000547_GR
- KEGG:   bmn:BMA10247_A0895
- TIGR:   BMA10247_A0895
- HOGENOM:   HBG423997
- OMA:   ITHVAQV
- ProtClustDB:   PRK13479
- BioCyc:   BMAL320389:BMA10247_A0895-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 38859; Mature: 38728

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVP
CCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAH
ECCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALA
HHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHH
ASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCC
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEE
TFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGA
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LESLGIAMR
HHHCCCCCC
>Mature Secondary Structure 
PERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVP
CCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAH
ECCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALA
HHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHH
ASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCC
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEE
TFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGA
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LESLGIAMR
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA