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The map label for this gene is prpR [H]

Identifier: 126443105

GI number: 126443105

Start: 344763

End: 346874

Strand: Reverse

Name: prpR [H]

Synonym: BURPS668_A0381

Alternate gene names: 126443105

Gene position: 346874-344763 (Counterclockwise)

Preceding gene: 126442663

Following gene: 126443650

Centisome position: 11.09

GC content: 73.91

Gene sequence:

>2112_bases
ATGAGCACCCTACCCGAAACCGGCGTGCGGCCGCGCGTCTGGGCGGTCGGCATCAGCCGGCTGCGCGCGCTCTTTCGCGA
CATCGCCGACGAATACGAAGAACGCGCCGATCTGCGGATCGTCGCGCGCGGCTACGAGGAGGCGATCACGGCGCTCGCGA
CGGCGGGCGCCGAGCGCCCCGACGCGATCGTCGCCGCCGGCTCGAACGGCACCTATCTGAAGGCGCGCGTGCGCGTGCCC
GTCGTGCTCGTCAATCCGACCGGCTTCGACGTGATGCACGCGCTCGCGCGGGCGCGGCGCGATGCGGGCCGGATCGCGCT
CGTCAGCTACGGCGAGACGCCGCCCGAGGTGCGCAGTTTCGCGGCCGCGTACGGGCTCGACGTCGTGTTCGCGTCGTACC
AGAGCGCGCAGGAGGCGGACACGCGCGTGCTCGAGATGCGCGAGCGCGGCATCGAGACCGTCGTCGGGCCGGGGCTCGTC
ACCGATCTCGCGGCGAACGCCGGGATGGGCGCGGTGTTCGTCTATTCGCACGCGTCGGTGCGCGCCGCCGTGAACACCGC
GCTCGAGGTCGCGCACGCGACGCACGCGGAAGCGCTGCGCCGCGAGCGCCTCGACAACCTGCTGCAGCACCTGCGCGACG
GCGTGGTGGCGCTCGACCGCGAGGGCCGCATCGAGGCGATCAACGAGCGGCTCGCGCTCGCGCTCGGCGTATCGCCGTCG
GCCGCGGTGGGCCGCGCGCTGGACGATCTGACGCCCGAGCTGCGCACGCTGCGCGCGGCCGACGGCGACACGCTCGCGAC
GGTGCGCGGCGTGCGCTACGTCGTGCATCGCGGGCCGCTCGCCTCGAGCGGCGGCGCGCCCGGCAGCGTGCTGACGTTCC
AGGAATCGCGTGCGGTCGAGCGGCTCGACCGCACGCTGCGCTCGCATCAGCACGCGCAGCAGTTCACCGCGCGCTACCGG
CTCGACGACATCGTCGGCACGACGCCCGCGATCGCGTACGCGCGCGACCTCGCGCGGCGCTACGCGAAATCGGACGCGAC
CGTGCTGATCCTCGGCGAGAGCGGCACCGGCAAGGAGATGATCGCGCAGAGCCTGCACGCGCTGTCCGCGCGCCGCAAGT
ATCCGTTCGTCGCGGTCAACTGCGGCGCGTTTCCGGAATCGCTGCTCGAGAGCGAGCTGTTCGGCTACGAGGAAGGCGCG
TTCACCGGCGCGCGGCGCGGCGGCAAGGCGGGGCTGTTCGAGGCCGCGCACCGCGGCACGCTGTTTCTCGACGAGATCGG
CGAAATGCCCCCGTCGCTGCAAAGCCGGCTGCTGCGCGTGCTGCAGGAGCGCGAGGTCGTGCGCGTCGGCTCGACCGAGC
CGGTTCCGGTCGACATCCGCGTCGTCGCCGCGACGCACCGGCCGCTCTTCGCCGCCGTCGAGGCGGGCACGTTCCGCGCG
GATCTCTATTACCGGCTGAACATCCTGAACATCGGGCTGCCGCCGCTGCGCGAGCGCGCGGCCGACATTCCGGCGCTCGC
CGCGACGCTGCTCGCGCAGGCCGCGCGCCGCGAGCCGCGGCTCGCCGAGCGGCTGCGCGACGCCAACGATGCGGCGCGCG
CGCTCGACGCGGCGAACGCCGCGCTCGCCCGCTATCGATGGCCGGGCAACGTGCGCGAATTGCAGAACGTGATCGAGCGC
ATCGCCGTCGAGCTCGCCGACGCGGGCGAGCGCGGCGATGCGGCCGTGAGCGCCGACACGCTGCGCGCGATCGCGCCCGA
GGTGTTCGCGCTCGATACGCTCGGCGGGTTCGGCTCGTTCGGCTCGTTCGGCTCGTTCGGCTCGGCGGCGGGCGGCGGGC
ACGGCGACGCGAGCGGCGGAGATATCGATGCCGATGCCGACGCGCGACGCCCGACGCTCGTGCAGCGCCGCCGGCGCGCG
GAAGCCGACGAGATTCGCGCGGCGCTCGACGCATGCGGCGGCGACCGCGACCGCGCGTGCGCGAGGCTCGGCATCAGCAA
GACGACGCTGTGGCGCAAGCTCGCGGCGAGCGAAGGGAAAGCGCGAGGCAATAAGCGCGGCGAGCGCGGCGGCGGCCACG
GCGGCGACAACGACGAAGGCGCGGGTGCGTGA

Upstream 100 bases:

>100_bases
ATATTGAAATTGAAATTCCATAATTGAAATCCATGCGCGATAATGTGGTTCATCCCCTCTCTTCATCCGGGCGCGGCTCG
CGCCGCGCCCTCGGTCCAGT

Downstream 100 bases:

>100_bases
CCTCGCGCGGGAAGGTCGCGGTTCCTGATTCCCGGTTTCCGTTCGCCGACTGCCGGCGCGCGAGCATTCGAGCGTCGTGC
GGGCTTCGCTTCGCGCGCGC

Product: propionate catabolism operon regulatory protein PrpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVP
VVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLV
TDLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYR
LDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGA
FTGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIER
IAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRA
EADEIRAALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGERGGGHGGDNDEGAGA

Sequences:

>Translated_703_residues
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVP
VVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLV
TDLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYR
LDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGA
FTGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIER
IAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRA
EADEIRAALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGERGGGHGGDNDEGAGA
>Mature_702_residues
STLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVPV
VLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVT
DLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPSA
AVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYRL
DDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAF
TGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRAD
LYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIERI
AVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAE
ADEIRAALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGERGGGHGGDNDEGAGA

Specific function: Involved In The Transcriptional Regulation Of The Propionate Catabolism Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=284, Percent_Identity=52.4647887323944, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1788550, Length=274, Percent_Identity=48.9051094890511, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI1789233, Length=383, Percent_Identity=35.7702349869452, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI87082117, Length=270, Percent_Identity=48.1481481481481, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI1790437, Length=356, Percent_Identity=42.9775280898876, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1788905, Length=259, Percent_Identity=49.8069498069498, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1790299, Length=275, Percent_Identity=46.5454545454545, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789087, Length=281, Percent_Identity=45.5516014234875, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI87082152, Length=253, Percent_Identity=45.4545454545455, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI87081872, Length=249, Percent_Identity=44.9799196787149, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=36.9281045751634, Blast_Score=187, Evalue=3e-48,
Organism=Escherichia coli, GI87081858, Length=482, Percent_Identity=28.2157676348548, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=37.5, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 75114; Mature: 74982

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
DAIVAAGSNGTYLKARVRVPVVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSF
CEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVTDLAANAGMGAVFVYSHASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCCEEEEEECHHH
RAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHEEEECCCCH
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVE
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
RLDRTLRSHQHAQQFTARYRLDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
IAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAFTGARRGGKAGLFEAAHRGT
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC
LFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
EEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEEECCCCEEEEECCCCEEE
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANA
EEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHH
ALARYRWPGNVRELQNVIERIAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSF
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHEECCCCCCCCC
GSFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIRAALDACGGDRDRAC
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
ARLGISKTTLWRKLAASEGKARGNKRGERGGGHGGDNDEGAGA
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
DAIVAAGSNGTYLKARVRVPVVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSF
CEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVTDLAANAGMGAVFVYSHASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCCEEEEEECHHH
RAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHEEEECCCCH
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVE
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
RLDRTLRSHQHAQQFTARYRLDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
IAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAFTGARRGGKAGLFEAAHRGT
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC
LFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
EEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEEECCCCEEEEECCCCEEE
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANA
EEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHH
ALARYRWPGNVRELQNVIERIAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSF
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHEECCCCCCCCC
GSFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIRAALDACGGDRDRAC
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
ARLGISKTTLWRKLAASEGKARGNKRGERGGGHGGDNDEGAGA
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA