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The map label for this gene is prmA

Identifier: 126209001

GI number: 126209001

Start: 1751577

End: 1752458

Strand: Reverse

Name: prmA

Synonym: APL_1537

Alternate gene names: 126209001

Gene position: 1752458-1751577 (Counterclockwise)

Preceding gene: 126209002

Following gene: 126208998

Centisome position: 77.05

GC content: 46.15

Gene sequence:

>882_bases
ATGGCATGGGTACAAATTCGTTTAAATAGTACGGATAAACAGGCTGAGCAAATCAGTGATTTTTTAGAAGAAATCGGGGC
GGTGTCGGTAACTTTTATGGACAGTCAGGATACGCCGATTTTTGAGCCGTTACCGGGAGAAACCCGTTTATGGGGTAATA
CGGACGTAGTGGGTTTATTTGATGCGGAAACCGATATGAAAGCGATTGTTGAAGCATTAATTGCCAGCCGTTTAGTCGAA
GCGGATTTTGCACATAAGATTGAGCAAATCGAAGATAAAGACTGGGAGCGTGAATGGATGGATAACTTCCACCCGATGCA
ATTCGGTAAACGCTTATGGATTTGTCCAAGTTGGCGTGAAGTACCGGATCCGAATGCGGTGAACGTGATGCTTGACCCTG
GTCTTGCTTTCGGTACCGGTACGCATCCGACGACCGCACTTTGTTTGCAATGGTTGGATAGCTTAGATTTAACCGGTAAA
ACGGTAATCGATTTCGGTTGCGGCTCCGGTATTTTGGCGATTGCAGCACTTAAACTCGGTGCAAAACAAGCGATCGGGAT
TGATATCGACCCACAGGCGATTTTAGCTTCGGGTAATAATGCGGAAGCTAACGGTGTGGCGGATCGTTTACAGTTATTCT
TAGCGAAAGATCAACCGCAAGATCTACAAGCCGATGTAGTGGTGGCGAATATTCTTGCCGGTCCACTGAAAGAGCTTGCA
CCAAATATTATTACGTTGGTGAAACCGCAAGGCGATTTAGGTTTATCCGGTATTTTAGCAACGCAAGCGGAATCGGTTTG
CGAAGCCTATGCACCGGACTTCAATCTTGATCCGGTGGTAGAAAAAGAAGAGTGGTGTCGTATTACCGGCGTGAAGAAAT
AG

Upstream 100 bases:

>100_bases
TAATGTTAAAACTCTAAACAAGCGGTCATTTTTGACTGATATTTTACAAATTATCGGTTTTCATTTGAGGAAAGCGGATA
AAAACAAGGAAAAAAATAAT

Downstream 100 bases:

>100_bases
TTTAACGTAATAAAAAGCGGTCGGATTTTGTAGAAAATTTGCAAAATCCGACCGCTTTTTTATGCCCTAGTTTACGAGAG
CTTGACGCAGTTTTCCATGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLFDAETDMKAIVEALIASRLVE
ADFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWREVPDPNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGK
TVIDFGCGSGILAIAALKLGAKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELA
PNIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDPVVEKEEWCRITGVKK

Sequences:

>Translated_293_residues
MAWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLFDAETDMKAIVEALIASRLVE
ADFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWREVPDPNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGK
TVIDFGCGSGILAIAALKLGAKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELA
PNIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDPVVEKEEWCRITGVKK
>Mature_292_residues
AWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLFDAETDMKAIVEALIASRLVEA
DFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWREVPDPNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGKT
VIDFGCGSGILAIAALKLGAKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELAP
NIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDPVVEKEEWCRITGVKK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=77.1331058020478, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_ACTP2 (A3N2I5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054226.1
- ProteinModelPortal:   A3N2I5
- SMR:   A3N2I5
- STRING:   A3N2I5
- GeneID:   4849675
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1537
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- PhylomeDB:   A3N2I5
- ProtClustDB:   PRK00517
- BioCyc:   APLE416269:APL_1537-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31982; Mature: 31851

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLF
CEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMKAIVEALIASRLVEADFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRE
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHC
AKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELA
CCCEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PNIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDPVVEKEEWCRITGVKK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEECCCCC
>Mature Secondary Structure 
AWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLF
EEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMKAIVEALIASRLVEADFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRE
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHC
AKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELA
CCCEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PNIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDPVVEKEEWCRITGVKK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA