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The map label for this gene is rpoE [H]

Identifier: 126207878

GI number: 126207878

Start: 449086

End: 449664

Strand: Direct

Name: rpoE [H]

Synonym: APL_0394

Alternate gene names: 126207878

Gene position: 449086-449664 (Clockwise)

Preceding gene: 126207877

Following gene: 126207879

Centisome position: 19.74

GC content: 41.28

Gene sequence:

>579_bases
ATGAGTGAGCTGGTAGCCGATCAAGAATTGGTTGAACGTGCACAGAAAGGTGATAAAAAAGCATTTAATTTACTCGTCGT
ACGTTATCAGAATAGAGTGGCAGGTTTATTAACTCGCTATGTTTCACGTGATGATATTCCGGATATTGTGCAGGAATCTT
TTATTAAAGCGTATCGTTCATTAGAGTCTTTCCGTGGAGAGAGCGCCTTTTATACGTGGCTTTATCGTATTGCGGTGAAC
ACTGCTAAAAATCATTTAACCGCTTTGGGAAGACGTCCTCCTAAAGAAGATATTTTGGCGGAAGATGCGGAGAGCTTTGA
TGTTGGGGGTCAACTTCGTGAGAGTGATACACCGGAAAATGTGGTGCTATCCGAAGAATTAAAACGTGTCGTTTTTGACA
CGATTGAAAATTTACCTGAAGAACTCAAAACGGCAATTACTTTGAGTGAGTTGGAAGGTTTAAGTTATGAAGAAATTGCG
GAAGTCATGCAATGTCCCGTCGGTACGGTTCGTTCGCGTATCTTTAGAGCAAGAGAAGCGATTGATGCAAAGGTCAATCC
GCTAATGCAACAGATTTAA

Upstream 100 bases:

>100_bases
TTATTCTTTATATGAACTTTTCATTTTTGTTACACACTAAAGGATGTACGGAATGAGAACAATAAGGAATATGCGAAATA
GATTAGGAGAACGCAAATAG

Downstream 100 bases:

>100_bases
GATTCAATCGGAGTTTATTATGCAACAAAATGAAACCCTTTCCGCTTTTATGGACGGGAAAAAAGTTGATGATGCGTTCA
TCGACGAGTTATGCGAAAGT

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSELVADQELVERAQKGDKKAFNLLVVRYQNRVAGLLTRYVSRDDIPDIVQESFIKAYRSLESFRGESAFYTWLYRIAVN
TAKNHLTALGRRPPKEDILAEDAESFDVGGQLRESDTPENVVLSEELKRVVFDTIENLPEELKTAITLSELEGLSYEEIA
EVMQCPVGTVRSRIFRAREAIDAKVNPLMQQI

Sequences:

>Translated_192_residues
MSELVADQELVERAQKGDKKAFNLLVVRYQNRVAGLLTRYVSRDDIPDIVQESFIKAYRSLESFRGESAFYTWLYRIAVN
TAKNHLTALGRRPPKEDILAEDAESFDVGGQLRESDTPENVVLSEELKRVVFDTIENLPEELKTAITLSELEGLSYEEIA
EVMQCPVGTVRSRIFRAREAIDAKVNPLMQQI
>Mature_191_residues
SELVADQELVERAQKGDKKAFNLLVVRYQNRVAGLLTRYVSRDDIPDIVQESFIKAYRSLESFRGESAFYTWLYRIAVNT
AKNHLTALGRRPPKEDILAEDAESFDVGGQLRESDTPENVVLSEELKRVVFDTIENLPEELKTAITLSELEGLSYEEIAE
VMQCPVGTVRSRIFRAREAIDAKVNPLMQQI

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=70.1570680628272, Blast_Score=284, Evalue=3e-78,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21852; Mature: 21721

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELVADQELVERAQKGDKKAFNLLVVRYQNRVAGLLTRYVSRDDIPDIVQESFIKAYRS
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LESFRGESAFYTWLYRIAVNTAKNHLTALGRRPPKEDILAEDAESFDVGGQLRESDTPEN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHCCCCCCCCCCCCCH
VVLSEELKRVVFDTIENLPEELKTAITLSELEGLSYEEIAEVMQCPVGTVRSRIFRAREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
IDAKVNPLMQQI
HHHHHHHHHHHC
>Mature Secondary Structure 
SELVADQELVERAQKGDKKAFNLLVVRYQNRVAGLLTRYVSRDDIPDIVQESFIKAYRS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LESFRGESAFYTWLYRIAVNTAKNHLTALGRRPPKEDILAEDAESFDVGGQLRESDTPEN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHCCCCCCCCCCCCCH
VVLSEELKRVVFDTIENLPEELKTAITLSELEGLSYEEIAEVMQCPVGTVRSRIFRAREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
IDAKVNPLMQQI
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]