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The map label for this gene is pepC

Identifier: 126207823

GI number: 126207823

Start: 373967

End: 376606

Strand: Reverse

Name: pepC

Synonym: APL_0339

Alternate gene names: 126207823

Gene position: 376606-373967 (Counterclockwise)

Preceding gene: 126207824

Following gene: 126207822

Centisome position: 16.56

GC content: 46.59

Gene sequence:

>2640_bases
ATGAATCAACCCTACTCCGCTATGCGTAACAACATCCATATGCTTGGTGATTTTTTAGGCGAAACCATTCGAGAAGCCCA
AGGCAACGAAATATTGGAATTAATTGAAAGCATCCGAGTACTTTCAAGAGATTCTCGTGCAGGCGATGAAAAAGCCCGTG
AACAATTACTGGATAAACTCGCCAATATTTCCACCGAAAATGTTTTACCCGTTGCACGCGCATTCAGTCAATTCTTAAAT
CTCACCAATATTGCCGAACAATATCAAACCATCTCTCGTCATCATCAGGACGAATCTCTCGGCAATCGTTCATTAAGTGC
TTTATTTGCTCGTCTAAAAGCACAAGGCACACCGGTTGAAACCGTCATCAAAACCGTTGAGAAGTTATCAATCGAATTAG
TCTTAACCGCTCACCCGACCGAAGTAACTCGCCGTTCGTTAGTACATAAACACGTTGAAATCAATAAATGTTTAGGGCAA
TTGGAACACGACGATTTAACCGAGGCGGAGCAAACCAAACTTAAACGCCGTTTAATGCAGCTGATTGCGCTTGCATGGCA
TACCAATGAAATCCGTGCGGCACGTCCGACGCCGGTGGATGAAGCGAAATGGGGAATGGCGATTATTGAAAACAGCTTAT
GGAAAGCCGTACCTGATTTTTGCCGTGAACTGAACTTTCAATTAGAAAAACATTTTGACGTACAGTATGAAGTCGCACTT
TCGCCGGTACGCTTTTCTTCTTGGATGGGCGGCGACCGTGACGGCAACCCGTTTGTGACTGCCGAAATCACACAAAAAGT
ATTAAGAATGAACCGTTGGAAAGCAGCGGAATTATTTTTAAACGATGTTAGCGACTTGGTCGAAGAACTTTCTATCGTAC
AGTGTACGCCCGAATTTCGTGAGAAATACGGCGATCATATCGAGCCGTATCGCGTTGTGGTTAAAGGTTTACGTAGCAAA
TTACAAAAAACTTTAACTTACTTCGGCGAATTGATTGAAGCGAAACCGACCACTGTTGATCCGAGCGAAATTATCACTTG
CGATAATGATTTATGGGAACCGCTCTATGATTGCTATCAATCGTTGCACGCTTGCGGTATGCGTATTATCGCTAACGGTA
GTCTGTTGGACTGCTTACGCCGTATTCGTTGCTTCGGCTTAGGTTTATCTCGTTTGGATATTCGTCAAGAAAGCTCCCGC
CACGAAACGGCAATTGCCGAAATCACTCGCTATATCGGCTTAGGCGATTACGCACAATGGACGGAAGACGATAAACAAGC
GTTTTTAGTGCGTGAACTAAGTTCTCGTCGTCCGTTAGTACCGACCAACTGGACGCCAAGTCCTGAAACCCAAGAAATTT
TAGACACTTGCAAAGTGGTAGCCCAACAACCTGAAGGGACGATTTCCGCTTATGTGATTTCTATGGCACGCGAAGCTTCC
GACGTATTAGCGGTACATTTATTATTAAAAGAAGCCGGTTGCAATTATACCCTACCGGTCGCACCGTTATTTGAAACGTT
GGACGACTTGGATCATAGTGAAAAAGTGATGACCGATTTATTTAATATCGGTTGGTATCGCGGTGTGATCAACAATTATC
AAATGGTGATGATCGGTTATTCCGATTCGGCTAAAGACGCCGGTATGCTTGCCGCCAGCTGGGCGCAATATCGCGCGCAA
GAAGCATTGGTTAATTTAGCGGAAAAATATCATATTGAACTCGTTTTATTCCACGGGCGCGGCGGTACGGTCGGTCGCGG
CGGTGCGCCGGCACACGCGGCATTACTATCACAACCGCCTCGCTCGCTAAAATCCGGTTTACGCGTCACCGAACAAGGCG
AGATGATCCGCTTCAAACTCGGCTTACCCGCTGTTGCGGTCGAAACGTTAAATCTCTATGCAAGTGCGATTTTAGAGGCC
AACTTATTACCGCCGCCGGAACCGAAACAAAAGTGGCGAGATATTATGGATAAAGGCGCGGCAATTTCTTGTGAAATTTA
TCGCGGCGTTGTTCGCGGCGAACCGGATTTTGTCCCGTATTTCCGCAGTGCGACCCCAGAACAAGAATTAGGGAAATTAC
CGCTCGGCTCTCGTCCTTCAAAACGTAATCCGAACGGTGGTGTGGAAAGCCTACGCGCGATTCCTTGGATTTTCGCTTGG
ATGCAAAACCGTTTGATGTTACCGGCTTGGCTTGGTGCCGGCGCGGCACTGCGCCAAATGATCGAACAAGGCGAGGAAAG
TACGCTTAAAGAAATGTGTAACGAATGGCCGTTCTTCTCTACCCGTATCGGTATGCTGGAAATGGTGTTCTCGAAAGCGG
ATTTATGGCTTGCGGAACATTACGACCAACGTTTGGTGGCAAAAGAGTTACACCGTTTAGGTAAAACGCTTCGTGCGCAA
TTATCGGCGGACATTCAAACGGTATTGACACTTGCGCACGACGGACAGCTTATGGCGGATTTACCTTGGATTGCCGAATC
TATCGCCTTACGTAACGTCTATACCGACCCGCTCAATTTACTGCAAGTAGAACTGCTGCAACGTTTACGTAGCCAAGGTG
AGGTAAGAGATCCGCAATTGGAACAAGCCTTAATGATCACAATTACCGGCATTGCGGCGGGTATGCGTAATACCGGTTAG

Upstream 100 bases:

>100_bases
ATCATTATTTTATAAAATTAATTAATTCCTTATTGCTATTTTGACTCATTTTAGGTATATCTACCCCTAATTAAATTTAT
GCAATACATAGGAAAAAATT

Downstream 100 bases:

>100_bases
CTTGTAAAATTACGAAAAAATCGGACCGCTTACGTTAAGCAAGCGGTCTGATTTCACTGAAAGTTTACGCACTCTTACGC
GATTTCTCACTTCCCATTGC

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 879; Mature: 879

Protein sequence:

>879_residues
MNQPYSAMRNNIHMLGDFLGETIREAQGNEILELIESIRVLSRDSRAGDEKAREQLLDKLANISTENVLPVARAFSQFLN
LTNIAEQYQTISRHHQDESLGNRSLSALFARLKAQGTPVETVIKTVEKLSIELVLTAHPTEVTRRSLVHKHVEINKCLGQ
LEHDDLTEAEQTKLKRRLMQLIALAWHTNEIRAARPTPVDEAKWGMAIIENSLWKAVPDFCRELNFQLEKHFDVQYEVAL
SPVRFSSWMGGDRDGNPFVTAEITQKVLRMNRWKAAELFLNDVSDLVEELSIVQCTPEFREKYGDHIEPYRVVVKGLRSK
LQKTLTYFGELIEAKPTTVDPSEIITCDNDLWEPLYDCYQSLHACGMRIIANGSLLDCLRRIRCFGLGLSRLDIRQESSR
HETAIAEITRYIGLGDYAQWTEDDKQAFLVRELSSRRPLVPTNWTPSPETQEILDTCKVVAQQPEGTISAYVISMAREAS
DVLAVHLLLKEAGCNYTLPVAPLFETLDDLDHSEKVMTDLFNIGWYRGVINNYQMVMIGYSDSAKDAGMLAASWAQYRAQ
EALVNLAEKYHIELVLFHGRGGTVGRGGAPAHAALLSQPPRSLKSGLRVTEQGEMIRFKLGLPAVAVETLNLYASAILEA
NLLPPPEPKQKWRDIMDKGAAISCEIYRGVVRGEPDFVPYFRSATPEQELGKLPLGSRPSKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGAALRQMIEQGEESTLKEMCNEWPFFSTRIGMLEMVFSKADLWLAEHYDQRLVAKELHRLGKTLRAQ
LSADIQTVLTLAHDGQLMADLPWIAESIALRNVYTDPLNLLQVELLQRLRSQGEVRDPQLEQALMITITGIAAGMRNTG

Sequences:

>Translated_879_residues
MNQPYSAMRNNIHMLGDFLGETIREAQGNEILELIESIRVLSRDSRAGDEKAREQLLDKLANISTENVLPVARAFSQFLN
LTNIAEQYQTISRHHQDESLGNRSLSALFARLKAQGTPVETVIKTVEKLSIELVLTAHPTEVTRRSLVHKHVEINKCLGQ
LEHDDLTEAEQTKLKRRLMQLIALAWHTNEIRAARPTPVDEAKWGMAIIENSLWKAVPDFCRELNFQLEKHFDVQYEVAL
SPVRFSSWMGGDRDGNPFVTAEITQKVLRMNRWKAAELFLNDVSDLVEELSIVQCTPEFREKYGDHIEPYRVVVKGLRSK
LQKTLTYFGELIEAKPTTVDPSEIITCDNDLWEPLYDCYQSLHACGMRIIANGSLLDCLRRIRCFGLGLSRLDIRQESSR
HETAIAEITRYIGLGDYAQWTEDDKQAFLVRELSSRRPLVPTNWTPSPETQEILDTCKVVAQQPEGTISAYVISMAREAS
DVLAVHLLLKEAGCNYTLPVAPLFETLDDLDHSEKVMTDLFNIGWYRGVINNYQMVMIGYSDSAKDAGMLAASWAQYRAQ
EALVNLAEKYHIELVLFHGRGGTVGRGGAPAHAALLSQPPRSLKSGLRVTEQGEMIRFKLGLPAVAVETLNLYASAILEA
NLLPPPEPKQKWRDIMDKGAAISCEIYRGVVRGEPDFVPYFRSATPEQELGKLPLGSRPSKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGAALRQMIEQGEESTLKEMCNEWPFFSTRIGMLEMVFSKADLWLAEHYDQRLVAKELHRLGKTLRAQ
LSADIQTVLTLAHDGQLMADLPWIAESIALRNVYTDPLNLLQVELLQRLRSQGEVRDPQLEQALMITITGIAAGMRNTG
>Mature_879_residues
MNQPYSAMRNNIHMLGDFLGETIREAQGNEILELIESIRVLSRDSRAGDEKAREQLLDKLANISTENVLPVARAFSQFLN
LTNIAEQYQTISRHHQDESLGNRSLSALFARLKAQGTPVETVIKTVEKLSIELVLTAHPTEVTRRSLVHKHVEINKCLGQ
LEHDDLTEAEQTKLKRRLMQLIALAWHTNEIRAARPTPVDEAKWGMAIIENSLWKAVPDFCRELNFQLEKHFDVQYEVAL
SPVRFSSWMGGDRDGNPFVTAEITQKVLRMNRWKAAELFLNDVSDLVEELSIVQCTPEFREKYGDHIEPYRVVVKGLRSK
LQKTLTYFGELIEAKPTTVDPSEIITCDNDLWEPLYDCYQSLHACGMRIIANGSLLDCLRRIRCFGLGLSRLDIRQESSR
HETAIAEITRYIGLGDYAQWTEDDKQAFLVRELSSRRPLVPTNWTPSPETQEILDTCKVVAQQPEGTISAYVISMAREAS
DVLAVHLLLKEAGCNYTLPVAPLFETLDDLDHSEKVMTDLFNIGWYRGVINNYQMVMIGYSDSAKDAGMLAASWAQYRAQ
EALVNLAEKYHIELVLFHGRGGTVGRGGAPAHAALLSQPPRSLKSGLRVTEQGEMIRFKLGLPAVAVETLNLYASAILEA
NLLPPPEPKQKWRDIMDKGAAISCEIYRGVVRGEPDFVPYFRSATPEQELGKLPLGSRPSKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGAALRQMIEQGEESTLKEMCNEWPFFSTRIGMLEMVFSKADLWLAEHYDQRLVAKELHRLGKTLRAQ
LSADIQTVLTLAHDGQLMADLPWIAESIALRNVYTDPLNLLQVELLQRLRSQGEVRDPQLEQALMITITGIAAGMRNTG

Specific function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG2352

COG function: function code C; Phosphoenolpyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 1 family

Homologues:

Organism=Escherichia coli, GI1790393, Length=886, Percent_Identity=63.882618510158, Blast_Score=1146, Evalue=0.0,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CAPP_ACTP2 (A3MZ57)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053048.1
- ProteinModelPortal:   A3MZ57
- SMR:   A3MZ57
- STRING:   A3MZ57
- GeneID:   4848495
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0339
- eggNOG:   COG2352
- HOGENOM:   HBG351035
- OMA:   AIPWVFG
- PhylomeDB:   A3MZ57
- ProtClustDB:   PRK00009
- BioCyc:   APLE416269:APL_0339-MONOMER
- HAMAP:   MF_00595
- InterPro:   IPR021135
- InterPro:   IPR018129
- InterPro:   IPR022805
- InterPro:   IPR015813
- PRINTS:   PR00150

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 99145; Mature: 99145

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00781 PEPCASE_1; PS00393 PEPCASE_2

Important sites: ACT_SITE 138-138 ACT_SITE 545-545

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPYSAMRNNIHMLGDFLGETIREAQGNEILELIESIRVLSRDSRAGDEKAREQLLDKL
CCCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ANISTENVLPVARAFSQFLNLTNIAEQYQTISRHHQDESLGNRSLSALFARLKAQGTPVE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHH
TVIKTVEKLSIELVLTAHPTEVTRRSLVHKHVEINKCLGQLEHDDLTEAEQTKLKRRLMQ
HHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LIALAWHTNEIRAARPTPVDEAKWGMAIIENSLWKAVPDFCRELNFQLEKHFDVQYEVAL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEE
SPVRFSSWMGGDRDGNPFVTAEITQKVLRMNRWKAAELFLNDVSDLVEELSIVQCTPEFR
CCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EKYGDHIEPYRVVVKGLRSKLQKTLTYFGELIEAKPTTVDPSEIITCDNDLWEPLYDCYQ
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHH
SLHACGMRIIANGSLLDCLRRIRCFGLGLSRLDIRQESSRHETAIAEITRYIGLGDYAQW
HHHHCCHHEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
TEDDKQAFLVRELSSRRPLVPTNWTPSPETQEILDTCKVVAQQPEGTISAYVISMAREAS
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DVLAVHLLLKEAGCNYTLPVAPLFETLDDLDHSEKVMTDLFNIGWYRGVINNYQMVMIGY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SDSAKDAGMLAASWAQYRAQEALVNLAEKYHIELVLFHGRGGTVGRGGAPAHAALLSQPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHCCCC
RSLKSGLRVTEQGEMIRFKLGLPAVAVETLNLYASAILEANLLPPPEPKQKWRDIMDKGA
HHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
AISCEIYRGVVRGEPDFVPYFRSATPEQELGKLPLGSRPSKRNPNGGVESLRAIPWIFAW
EEEHHHHHHHHCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MQNRLMLPAWLGAGAALRQMIEQGEESTLKEMCNEWPFFSTRIGMLEMVFSKADLWLAEH
HHCCEECHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YDQRLVAKELHRLGKTLRAQLSADIQTVLTLAHDGQLMADLPWIAESIALRNVYTDPLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LQVELLQRLRSQGEVRDPQLEQALMITITGIAAGMRNTG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNQPYSAMRNNIHMLGDFLGETIREAQGNEILELIESIRVLSRDSRAGDEKAREQLLDKL
CCCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ANISTENVLPVARAFSQFLNLTNIAEQYQTISRHHQDESLGNRSLSALFARLKAQGTPVE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHH
TVIKTVEKLSIELVLTAHPTEVTRRSLVHKHVEINKCLGQLEHDDLTEAEQTKLKRRLMQ
HHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LIALAWHTNEIRAARPTPVDEAKWGMAIIENSLWKAVPDFCRELNFQLEKHFDVQYEVAL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEE
SPVRFSSWMGGDRDGNPFVTAEITQKVLRMNRWKAAELFLNDVSDLVEELSIVQCTPEFR
CCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EKYGDHIEPYRVVVKGLRSKLQKTLTYFGELIEAKPTTVDPSEIITCDNDLWEPLYDCYQ
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHH
SLHACGMRIIANGSLLDCLRRIRCFGLGLSRLDIRQESSRHETAIAEITRYIGLGDYAQW
HHHHCCHHEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
TEDDKQAFLVRELSSRRPLVPTNWTPSPETQEILDTCKVVAQQPEGTISAYVISMAREAS
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DVLAVHLLLKEAGCNYTLPVAPLFETLDDLDHSEKVMTDLFNIGWYRGVINNYQMVMIGY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SDSAKDAGMLAASWAQYRAQEALVNLAEKYHIELVLFHGRGGTVGRGGAPAHAALLSQPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHCCCC
RSLKSGLRVTEQGEMIRFKLGLPAVAVETLNLYASAILEANLLPPPEPKQKWRDIMDKGA
HHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
AISCEIYRGVVRGEPDFVPYFRSATPEQELGKLPLGSRPSKRNPNGGVESLRAIPWIFAW
EEEHHHHHHHHCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MQNRLMLPAWLGAGAALRQMIEQGEESTLKEMCNEWPFFSTRIGMLEMVFSKADLWLAEH
HHCCEECHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YDQRLVAKELHRLGKTLRAQLSADIQTVLTLAHDGQLMADLPWIAESIALRNVYTDPLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LQVELLQRLRSQGEVRDPQLEQALMITITGIAAGMRNTG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA