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The map label for this gene is lptA [H]

Identifier: 126207821

GI number: 126207821

Start: 372683

End: 373186

Strand: Reverse

Name: lptA [H]

Synonym: APL_0337

Alternate gene names: 126207821

Gene position: 373186-372683 (Counterclockwise)

Preceding gene: 126207822

Following gene: 126207820

Centisome position: 16.41

GC content: 37.3

Gene sequence:

>504_bases
ATGAAATTTGCAATTAAATCTATGGTGTTTACGGCTTTATTAAGTACCAGCCTCTCGTCCTATGCACTCAAAGGCGATAC
CGACCAACCGATTAATATCGACTCGGGTAGCCAATCGCTTGATATGAATAGTAATGTCGTGACATTTAGCGATAATGTCG
TCATTACTCAAGGTTCGATTAAAGTTACCGCAGATAAAGTAACGATTATTCGTCAAGAGGGCAAAAAAGAGACCCTCGAA
GCAAGCGGTTCTCCGGTCACTTTCCAACAAACGTTGGATAACGGTAAACCGGTAAACGGAAAAGGTAATAGCGTTCACTA
TGATTTAAATTCCGAATTTTTAACCTTAGTCGGTAATGCGGAATTAAAACAGCAAGGTAGTTTTATCAAAGCCAGTAAAA
TTACTTATGATGTGAAAAAACAACAACTTAAAGCTAACAGCGGAAATAAATCTCGTGTCAAAACGATACTTATTCCGAAT
GAATTAAACGATAAGAAAAAATAG

Upstream 100 bases:

>100_bases
AACGATTACTAAAGATGTAAAAACGTATCTTGAACCGACAATCATTAAACAATCTAACGACGAACAAAAAAATTAGAGCA
TTTTCTCTGAAGGATACATA

Downstream 100 bases:

>100_bases
GTAATGCCAATGCCAACGCTTTATGCCGAACATTTAGCGAAAAGCTATAAAAATCGCCAAGTGGTAAAAGACGTCAGCTT
AAATGTTAAAGCCGGTGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKFAIKSMVFTALLSTSLSSYALKGDTDQPINIDSGSQSLDMNSNVVTFSDNVVITQGSIKVTADKVTIIRQEGKKETLE
ASGSPVTFQQTLDNGKPVNGKGNSVHYDLNSEFLTLVGNAELKQQGSFIKASKITYDVKKQQLKANSGNKSRVKTILIPN
ELNDKKK

Sequences:

>Translated_167_residues
MKFAIKSMVFTALLSTSLSSYALKGDTDQPINIDSGSQSLDMNSNVVTFSDNVVITQGSIKVTADKVTIIRQEGKKETLE
ASGSPVTFQQTLDNGKPVNGKGNSVHYDLNSEFLTLVGNAELKQQGSFIKASKITYDVKKQQLKANSGNKSRVKTILIPN
ELNDKKK
>Mature_167_residues
MKFAIKSMVFTALLSTSLSSYALKGDTDQPINIDSGSQSLDMNSNVVTFSDNVVITQGSIKVTADKVTIIRQEGKKETLE
ASGSPVTFQQTLDNGKPVNGKGNSVHYDLNSEFLTLVGNAELKQQGSFIKASKITYDVKKQQLKANSGNKSRVKTILIPN
ELNDKKK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=166, Percent_Identity=48.7951807228916, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 18159; Mature: 18159

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAIKSMVFTALLSTSLSSYALKGDTDQPINIDSGSQSLDMNSNVVTFSDNVVITQGSI
CCHHHHHHHHHHHHHHCHHHEEECCCCCCCEEECCCCCCCCCCCCEEEEECCEEEECCCE
KVTADKVTIIRQEGKKETLEASGSPVTFQQTLDNGKPVNGKGNSVHYDLNSEFLTLVGNA
EEEECEEEEEECCCCCCHHHCCCCCEEEHHHCCCCCCCCCCCCEEEEECCCCEEEEECCC
ELKQQGSFIKASKITYDVKKQQLKANSGNKSRVKTILIPNELNDKKK
CHHHCCCEEEEEEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKFAIKSMVFTALLSTSLSSYALKGDTDQPINIDSGSQSLDMNSNVVTFSDNVVITQGSI
CCHHHHHHHHHHHHHHCHHHEEECCCCCCCEEECCCCCCCCCCCCEEEEECCEEEECCCE
KVTADKVTIIRQEGKKETLEASGSPVTFQQTLDNGKPVNGKGNSVHYDLNSEFLTLVGNA
EEEECEEEEEECCCCCCHHHCCCCCEEEHHHCCCCCCCCCCCCEEEEECCCCEEEEECCC
ELKQQGSFIKASKITYDVKKQQLKANSGNKSRVKTILIPNELNDKKK
CHHHCCCEEEEEEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]