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The map label for this gene is yjjG [H]

Identifier: 126207620

GI number: 126207620

Start: 147527

End: 148207

Strand: Direct

Name: yjjG [H]

Synonym: APL_0132

Alternate gene names: 126207620

Gene position: 147527-148207 (Clockwise)

Preceding gene: 126207619

Following gene: 126207621

Centisome position: 6.49

GC content: 42.29

Gene sequence:

>681_bases
ATGAAGTATGATTGGGTTTTATTTGACGCTGACGAAACGCTTTTTTCGTTTAATTCGTACTTAGGTTTAACCTCTATGCT
GAAACGGTACGGTATTGAATTTACGCGAGAAGACTATGAGGCGTTTCAGGCGGTCAATAAACCGCTTTGGGTGGCTTATC
AGAATAATGAAATTACCGCTCAAGACATTCAAACCCGCCGTTTTGCCAAGTTATCGGCGCAAACCGGCATAGACGCATTG
CAACTTAATCAAGAGTTAATGGCGGAAATGGCATTGGTCAGTAAACCGTTGGACGGCGTGACGGCTATGTTGGAACAGCT
ATACGGTAAAGTAAAGATGGGGATTATCACTAACGGCTTTACCGAATTACAGCAAAAGCGATTAGCGAATACGCATACCG
AGAAATTTTTTGAGATTGTCGTCGTATCGGAACAAATCGGTGCAGCCAAGCCGGATCGACAGGTGTTCGATTACGCTTTT
ACTTTGATGGAACAGGAAGACAAAACCAAAGTGTTAATGGTTGGCGATACGCTTGCATCAGACGTTTTAGGCGGTAATAA
TGCGGGTATCGATACCTGTTGGTTTAATCATTCGAAAAGTAAGAATGAAACACAGATTCGCCCGACTTATGAAATTAGCT
CAATGGATCAGCTTATTGAGATTGTTAAAGGAACCGAATAA

Upstream 100 bases:

>100_bases
AGGCGTTTTACGTGGTTTATCCTCCGCAAATGGCAGAGATTGCGAAAGTTAAACATTTTGTCGAGTGGATTACGCATGAA
ATCAAAGGAAGTTATAAATA

Downstream 100 bases:

>100_bases
TGAAATTACAGCAATTACGCTACATCGTTGAAATTGTAAATCAAAATCTGAATATTACCGAAGCGGCGGAAACACTTTAC
ACTTCTCAACCGGGCATTAG

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKYDWVLFDADETLFSFNSYLGLTSMLKRYGIEFTREDYEAFQAVNKPLWVAYQNNEITAQDIQTRRFAKLSAQTGIDAL
QLNQELMAEMALVSKPLDGVTAMLEQLYGKVKMGIITNGFTELQQKRLANTHTEKFFEIVVVSEQIGAAKPDRQVFDYAF
TLMEQEDKTKVLMVGDTLASDVLGGNNAGIDTCWFNHSKSKNETQIRPTYEISSMDQLIEIVKGTE

Sequences:

>Translated_226_residues
MKYDWVLFDADETLFSFNSYLGLTSMLKRYGIEFTREDYEAFQAVNKPLWVAYQNNEITAQDIQTRRFAKLSAQTGIDAL
QLNQELMAEMALVSKPLDGVTAMLEQLYGKVKMGIITNGFTELQQKRLANTHTEKFFEIVVVSEQIGAAKPDRQVFDYAF
TLMEQEDKTKVLMVGDTLASDVLGGNNAGIDTCWFNHSKSKNETQIRPTYEISSMDQLIEIVKGTE
>Mature_226_residues
MKYDWVLFDADETLFSFNSYLGLTSMLKRYGIEFTREDYEAFQAVNKPLWVAYQNNEITAQDIQTRRFAKLSAQTGIDAL
QLNQELMAEMALVSKPLDGVTAMLEQLYGKVKMGIITNGFTELQQKRLANTHTEKFFEIVVVSEQIGAAKPDRQVFDYAF
TLMEQEDKTKVLMVGDTLASDVLGGNNAGIDTCWFNHSKSKNETQIRPTYEISSMDQLIEIVKGTE

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Escherichia coli, GI1790833, Length=222, Percent_Identity=45.045045045045, Blast_Score=224, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYDWVLFDADETLFSFNSYLGLTSMLKRYGIEFTREDYEAFQAVNKPLWVAYQNNEITA
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCH
QDIQTRRFAKLSAQTGIDALQLNQELMAEMALVSKPLDGVTAMLEQLYGKVKMGIITNGF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEHHEECCH
TELQQKRLANTHTEKFFEIVVVSEQIGAAKPDRQVFDYAFTLMEQEDKTKVLMVGDTLAS
HHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHH
DVLGGNNAGIDTCWFNHSKSKNETQIRPTYEISSMDQLIEIVKGTE
HHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYDWVLFDADETLFSFNSYLGLTSMLKRYGIEFTREDYEAFQAVNKPLWVAYQNNEITA
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCH
QDIQTRRFAKLSAQTGIDALQLNQELMAEMALVSKPLDGVTAMLEQLYGKVKMGIITNGF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEHHEECCH
TELQQKRLANTHTEKFFEIVVVSEQIGAAKPDRQVFDYAFTLMEQEDKTKVLMVGDTLAS
HHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHH
DVLGGNNAGIDTCWFNHSKSKNETQIRPTYEISSMDQLIEIVKGTE
HHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]