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The map label for this gene is engC

Identifier: 126207618

GI number: 126207618

Start: 145093

End: 146127

Strand: Reverse

Name: engC

Synonym: APL_0130

Alternate gene names: 126207618

Gene position: 146127-145093 (Counterclockwise)

Preceding gene: 126207623

Following gene: 126207617

Centisome position: 6.42

GC content: 41.84

Gene sequence:

>1035_bases
TTGAGTAAACGCAGACTGACCCAAAACCAACAACGCAGAATCAAATCGAATCATCATAAAAAAATCGCAAAACCCGAATT
GGAATGGCAAGACGAAATGCTAGGCGAAGTTCAACAAGGTATTGTGGTTACTCGCCATGCCAAACACGCCGATGTAGAAA
CCGAACAAGGTGAAATTTATCGTTGCAATCTTCGCCGTACTTTAAAAAACGTGGTGGTCGGCGATCAGGTGTCTTGGCGA
AAAGGCAACGAGCAGTTACAAGGCATTAGCGGTGTGATTGAAGCAATTTATCCGCGTAAAAATGAATTGAGCCGTCCCGA
TTATTATGACGGTATCAAAGTGATGGCGGCAAATATCGATCAAATCATTATTGTTTCCGCCGTATTACCCACACTTTCGC
TTAATATTATTGATCGCTACTTAGTGATTTGTGAAACCGCTAAAATTCCTGCGCTTATTGTGCTAAATAAAATTGATTTG
CTTTCGGAATCCGAACGACAAGAAGTGCAAAAGCAATTAGCCATTTATGAAAATATCGGTTATGAAACCCTTTGTCTGTC
TGCCGATACCGGTGAAAATATGGAAAAATTAGACCGCTATTTATCACGCGGCACTTCAATTTTCGTCGGACAATCCGGGG
TAGGAAAATCAAGCCTAATCAACCAATTATTACCGGAGGTTAATGCTTTGACCGGTGCGGTAAGCGATATTTCGGGATTA
GGTCAGCATACGACCACATCTTCTCGCTTATACCATTTACCGCAAGGGGGTAATTTAATTGACTCGCCGGGGATTCGTGA
ATTCGGTTTATGGCATTTAGAGCCGGAACAAATCACGCTTGGTTACCGTGAATTTCAATCGGTATTAGGCACATGTAAAT
TCCGAGATTGCAAACATAAATCGGATCCGGGCTGTGCGGTGAGAGAAGCGGTCGAAAAAGGTGAAATTAATGCAATTCGT
TTCGAAAACTATCATCGATTAATTGAAAGCCGTGATGAAACCAAAAGTCAGCGTCATTTTAGAACGGAAGAATAA

Upstream 100 bases:

>100_bases
TTTATCCGTCAGCTTCGATAACTTCATTCTTCCGATACTACATAAACAAAGCGATTTATAGTATCCTTTCAACTTATTTC
GATCATCTAAGAGAAATCCT

Downstream 100 bases:

>100_bases
AATTAAATAAGAATCAATAGCAATGAGTACAAATTTCATTTATCCTAATGCCCACTTGATCGCAGGTGTGGACGAAGTCG
GTAGAGGCCCGTTAGTCGGT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIYRCNLRRTLKNVVVGDQVSWR
KGNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANIDQIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDL
LSESERQEVQKQLAIYENIGYETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGL
GQHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHKSDPGCAVREAVEKGEINAIR
FENYHRLIESRDETKSQRHFRTEE

Sequences:

>Translated_344_residues
MSKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIYRCNLRRTLKNVVVGDQVSWR
KGNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANIDQIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDL
LSESERQEVQKQLAIYENIGYETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGL
GQHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHKSDPGCAVREAVEKGEINAIR
FENYHRLIESRDETKSQRHFRTEE
>Mature_343_residues
SKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIYRCNLRRTLKNVVVGDQVSWRK
GNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANIDQIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDLL
SESERQEVQKQLAIYENIGYETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGLG
QHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHKSDPGCAVREAVEKGEINAIRF
ENYHRLIESRDETKSQRHFRTEE

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=345, Percent_Identity=55.3623188405797, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_ACTP2 (A3MYK2)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052843.1
- ProteinModelPortal:   A3MYK2
- SMR:   A3MYK2
- STRING:   A3MYK2
- GeneID:   4848826
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0130
- eggNOG:   COG1162
- HOGENOM:   HBG652450
- OMA:   FRDCKHL
- PhylomeDB:   A3MYK2
- ProtClustDB:   PRK12288
- BioCyc:   APLE416269:APL_0130-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 39024; Mature: 38893

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIY
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCEE
RCNLRRTLKNVVVGDQVSWRKGNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANID
EEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHEECCCCC
QIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDLLSESERQEVQKQLAIYENIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHCCC
YETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGL
CEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GQHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHK
CCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECHHHEECCHHHHHHHHHCCCCCCCCCC
SDPGCAVREAVEKGEINAIRFENYHRLIESRDETKSQRHFRTEE
CCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKRRLTQNQQRRIKSNHHKKIAKPELEWQDEMLGEVQQGIVVTRHAKHADVETEQGEIY
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCEE
RCNLRRTLKNVVVGDQVSWRKGNEQLQGISGVIEAIYPRKNELSRPDYYDGIKVMAANID
EEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHEECCCCC
QIIIVSAVLPTLSLNIIDRYLVICETAKIPALIVLNKIDLLSESERQEVQKQLAIYENIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHCCC
YETLCLSADTGENMEKLDRYLSRGTSIFVGQSGVGKSSLINQLLPEVNALTGAVSDISGL
CEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GQHTTTSSRLYHLPQGGNLIDSPGIREFGLWHLEPEQITLGYREFQSVLGTCKFRDCKHK
CCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECHHHEECCHHHHHHHHHCCCCCCCCCC
SDPGCAVREAVEKGEINAIRFENYHRLIESRDETKSQRHFRTEE
CCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA