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The map label for this gene is prc [H]

Identifier: 126207608

GI number: 126207608

Start: 136190

End: 138202

Strand: Direct

Name: prc [H]

Synonym: APL_0120

Alternate gene names: 126207608

Gene position: 136190-138202 (Clockwise)

Preceding gene: 126207607

Following gene: 126207609

Centisome position: 5.99

GC content: 40.54

Gene sequence:

>2013_bases
ATGAAAATAAATCAACTTAGCCGTCTTATTGCTATTTGTTTCGGGACTATCGTAAGCAGTGCATTTGCGGTAGAACCGCA
AATTCAAGAGAGTGCGTTAGTAACCCCGAAACCGACGGAACAACACAGCCTTTCAACTAAACGTGTTACAGCGCGTTTGA
CACAATCTCACTACCATAAGTTTAAATTAGACGATGAGTTTGCGGATAAGATTTTTAACCGATATATGGATTGGTTAGAC
GGAGCGCATAATACTTTTTTACAATCCGATATTGATGAGATGCGCGCCAAATATGCGGCGAAATTAGATGATGAGCTGTA
TGAAGGTAAGTTGGATTCCGCATTTGAAATCTATGATTTAATGACCAAACGTCGTTATGGACGTTATAAGTATGCGTTGT
CTTTATTAGATAAAGAGCCGAATTTAAAAGGGTCGGATCAAATCGAAAATGATCGTGAAAAGGCGGCGTTTCCCGCAACG
GTTGAAGAAGCCAATCAGCTATGGGAACAACGTGTTAAAAACGATGTAATTAATCTCTATCTTAAAGATAAAAAATGGCC
TGAAATTAAGAAAACGTTAATTAAACGCTATAATTTAGCAATCAAACGTTTGACGCAAATTAAAGCGGACGATGTATTGC
AAACGTATTTAAATGCGTTCGCACGTGAAATTGATCCGCACACAAGTTATCTTTCGCCTCGTGCGGCAAAAGCATTCCAA
GAAAGTATGAATTTGTCTTTGGAAGGTATCGGTGCGACGCTTGCTATGGAAGACGACGTAACCACGATTAAATCTCTCGT
GCCGGGTGCGCCTGCCGCTCGTAGTAAAAAACTGGTGGTCGGCGATAAGATCGTAGGTGTCGGTCAGGATAACGATGAGA
TTGAAGATGTTATCGGCTGGCGTTTAGATGATGTTGTCGATAAGATCAAAGGTAAAAAAGGTACTAAAGTCCGTTTAGAA
ATTGAACCGGAAAAAGGCGGTAAAACGAAAGTTATCACTTTGGTTCGAGATAAAGTCCGTTTAGAAGACAGTGCGGCGAA
ATTAACCGTTGATAAAATTAACGGTAAAAATGTCGCGGTAATTAAAATTTCAACGTTTTACATCGGTTTGACCAATGATG
TGCGTAAATTATTAGATGAAATGAAAACTAAAAAAGTGGACGGTTTAATTATCGATTTACGTGAAAACGGCGGCGGTTCT
CTGACGGAAGTTGTTGAATTAACCGGACTCTTTATTAAAGACGGGCCGGTTGTTCAGGTTCGAGATGCGTTCAACCGTAT
TAAAGTGCATGAAGATCCGGAAGCGGATAAATCGCTTTATGACGGTAAGATCATGGTTATGATTAACCGCCACAGCGCGT
CGGCATCCGAAATTTTTGCTGCGGCGATGCAAGATTACAATCGTGCAATTATCGTAGGGCAACAAACCTTCGGTAAAGGT
ACGGTTCAACAAAGTCGTTCGTTAAATTTTGTATATGACTTGGATCAGGAACCGTTAGGCTTTATTCAATACACAATCCA
AAAATTCTATCGTATTGACGGCGGCAGCACTCAATTGAAAGGCGTCGAAGCGGATATTAAATTCCCTGAAATTATTAATG
CGGAGAAAACCGGCGAAAGTTTTGAAGATAATGCTTTACCTTGGGATAAAATTCCTGCGGCAAGCTATCAAGAAGCCGGA
CATGCAAGAGATGCGGTTTCCGCATTAACTGCTAAGCATGAAGAACGTATTGCGAAAGAACCTGAGTTTATTACGTTAAA
CGAAGATATTGCAATCCGTAAAGAAAGAGACGCTCGCAAGTATTCGTCACTGAATCTGGAAGAGCGTTTGAAAGAAGATC
GTGCCGACGAAGCGAAACGTCTGAAAGATCTGAATGCACGCTTTGCAAGGGAAGGGAAAAAAGCGATTAAGAATATTGAC
GCCTTACCGAAAGACTATGAAGCGCCGGACTTTTTCTTAAAAGAAGCTGAAAAAATGATGGTTGATTGGTTAGAAATTGA
TAAGAAGTCATAA

Upstream 100 bases:

>100_bases
AATAAATAATTTGCAGGTCTAGCGGTCGGTTTATTGTCGTTTTACAATACGTAACGTTTTTTTGACCGCTTGCATATCTT
TATAATGAATCAGGATTTTT

Downstream 100 bases:

>100_bases
AATAGCTTATAATGTATTAAATTAGCTGCCGCTTAATGAAAGTTAGGCGGTTTGCTTTTATTGATATTTTATAATCTCGG
AGCTAAGGATTTTTATATGA

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MKINQLSRLIAICFGTIVSSAFAVEPQIQESALVTPKPTEQHSLSTKRVTARLTQSHYHKFKLDDEFADKIFNRYMDWLD
GAHNTFLQSDIDEMRAKYAAKLDDELYEGKLDSAFEIYDLMTKRRYGRYKYALSLLDKEPNLKGSDQIENDREKAAFPAT
VEEANQLWEQRVKNDVINLYLKDKKWPEIKKTLIKRYNLAIKRLTQIKADDVLQTYLNAFAREIDPHTSYLSPRAAKAFQ
ESMNLSLEGIGATLAMEDDVTTIKSLVPGAPAARSKKLVVGDKIVGVGQDNDEIEDVIGWRLDDVVDKIKGKKGTKVRLE
IEPEKGGKTKVITLVRDKVRLEDSAAKLTVDKINGKNVAVIKISTFYIGLTNDVRKLLDEMKTKKVDGLIIDLRENGGGS
LTEVVELTGLFIKDGPVVQVRDAFNRIKVHEDPEADKSLYDGKIMVMINRHSASASEIFAAAMQDYNRAIIVGQQTFGKG
TVQQSRSLNFVYDLDQEPLGFIQYTIQKFYRIDGGSTQLKGVEADIKFPEIINAEKTGESFEDNALPWDKIPAASYQEAG
HARDAVSALTAKHEERIAKEPEFITLNEDIAIRKERDARKYSSLNLEERLKEDRADEAKRLKDLNARFAREGKKAIKNID
ALPKDYEAPDFFLKEAEKMMVDWLEIDKKS

Sequences:

>Translated_670_residues
MKINQLSRLIAICFGTIVSSAFAVEPQIQESALVTPKPTEQHSLSTKRVTARLTQSHYHKFKLDDEFADKIFNRYMDWLD
GAHNTFLQSDIDEMRAKYAAKLDDELYEGKLDSAFEIYDLMTKRRYGRYKYALSLLDKEPNLKGSDQIENDREKAAFPAT
VEEANQLWEQRVKNDVINLYLKDKKWPEIKKTLIKRYNLAIKRLTQIKADDVLQTYLNAFAREIDPHTSYLSPRAAKAFQ
ESMNLSLEGIGATLAMEDDVTTIKSLVPGAPAARSKKLVVGDKIVGVGQDNDEIEDVIGWRLDDVVDKIKGKKGTKVRLE
IEPEKGGKTKVITLVRDKVRLEDSAAKLTVDKINGKNVAVIKISTFYIGLTNDVRKLLDEMKTKKVDGLIIDLRENGGGS
LTEVVELTGLFIKDGPVVQVRDAFNRIKVHEDPEADKSLYDGKIMVMINRHSASASEIFAAAMQDYNRAIIVGQQTFGKG
TVQQSRSLNFVYDLDQEPLGFIQYTIQKFYRIDGGSTQLKGVEADIKFPEIINAEKTGESFEDNALPWDKIPAASYQEAG
HARDAVSALTAKHEERIAKEPEFITLNEDIAIRKERDARKYSSLNLEERLKEDRADEAKRLKDLNARFAREGKKAIKNID
ALPKDYEAPDFFLKEAEKMMVDWLEIDKKS
>Mature_670_residues
MKINQLSRLIAICFGTIVSSAFAVEPQIQESALVTPKPTEQHSLSTKRVTARLTQSHYHKFKLDDEFADKIFNRYMDWLD
GAHNTFLQSDIDEMRAKYAAKLDDELYEGKLDSAFEIYDLMTKRRYGRYKYALSLLDKEPNLKGSDQIENDREKAAFPAT
VEEANQLWEQRVKNDVINLYLKDKKWPEIKKTLIKRYNLAIKRLTQIKADDVLQTYLNAFAREIDPHTSYLSPRAAKAFQ
ESMNLSLEGIGATLAMEDDVTTIKSLVPGAPAARSKKLVVGDKIVGVGQDNDEIEDVIGWRLDDVVDKIKGKKGTKVRLE
IEPEKGGKTKVITLVRDKVRLEDSAAKLTVDKINGKNVAVIKISTFYIGLTNDVRKLLDEMKTKKVDGLIIDLRENGGGS
LTEVVELTGLFIKDGPVVQVRDAFNRIKVHEDPEADKSLYDGKIMVMINRHSASASEIFAAAMQDYNRAIIVGQQTFGKG
TVQQSRSLNFVYDLDQEPLGFIQYTIQKFYRIDGGSTQLKGVEADIKFPEIINAEKTGESFEDNALPWDKIPAASYQEAG
HARDAVSALTAKHEERIAKEPEFITLNEDIAIRKERDARKYSSLNLEERLKEDRADEAKRLKDLNARFAREGKKAIKNID
ALPKDYEAPDFFLKEAEKMMVDWLEIDKKS

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=674, Percent_Identity=50.593471810089, Blast_Score=640, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 75960; Mature: 75960

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINQLSRLIAICFGTIVSSAFAVEPQIQESALVTPKPTEQHSLSTKRVTARLTQSHYHK
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHE
FKLDDEFADKIFNRYMDWLDGAHNTFLQSDIDEMRAKYAAKLDDELYEGKLDSAFEIYDL
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MTKRRYGRYKYALSLLDKEPNLKGSDQIENDREKAAFPATVEEANQLWEQRVKNDVINLY
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHEEEE
LKDKKWPEIKKTLIKRYNLAIKRLTQIKADDVLQTYLNAFAREIDPHTSYLSPRAAKAFQ
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHH
ESMNLSLEGIGATLAMEDDVTTIKSLVPGAPAARSKKLVVGDKIVGVGQDNDEIEDVIGW
HHHCCEEEECCEEEEECCCHHHHHHHCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHCC
RLDDVVDKIKGKKGTKVRLEIEPEKGGKTKVITLVRDKVRLEDSAAKLTVDKINGKNVAV
CHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEHHHHHCCCCHHEEEEEECCCCEEEE
IKISTFYIGLTNDVRKLLDEMKTKKVDGLIIDLRENGGGSLTEVVELTGLFIKDGPVVQV
EEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCEEEE
RDAFNRIKVHEDPEADKSLYDGKIMVMINRHSASASEIFAAAMQDYNRAIIVGQQTFGKG
EHHHHHCCCCCCCCCCHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
TVQQSRSLNFVYDLDQEPLGFIQYTIQKFYRIDGGSTQLKGVEADIKFPEIINAEKTGES
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHCCCCCCCCC
FEDNALPWDKIPAASYQEAGHARDAVSALTAKHEERIAKEPEFITLNEDIAIRKERDARK
CCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEECCHHHHHH
YSSLNLEERLKEDRADEAKRLKDLNARFAREGKKAIKNIDALPKDYEAPDFFLKEAEKMM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VDWLEIDKKS
HHHHHHCCCC
>Mature Secondary Structure
MKINQLSRLIAICFGTIVSSAFAVEPQIQESALVTPKPTEQHSLSTKRVTARLTQSHYHK
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHE
FKLDDEFADKIFNRYMDWLDGAHNTFLQSDIDEMRAKYAAKLDDELYEGKLDSAFEIYDL
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MTKRRYGRYKYALSLLDKEPNLKGSDQIENDREKAAFPATVEEANQLWEQRVKNDVINLY
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHEEEE
LKDKKWPEIKKTLIKRYNLAIKRLTQIKADDVLQTYLNAFAREIDPHTSYLSPRAAKAFQ
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHH
ESMNLSLEGIGATLAMEDDVTTIKSLVPGAPAARSKKLVVGDKIVGVGQDNDEIEDVIGW
HHHCCEEEECCEEEEECCCHHHHHHHCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHCC
RLDDVVDKIKGKKGTKVRLEIEPEKGGKTKVITLVRDKVRLEDSAAKLTVDKINGKNVAV
CHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEHHHHHCCCCHHEEEEEECCCCEEEE
IKISTFYIGLTNDVRKLLDEMKTKKVDGLIIDLRENGGGSLTEVVELTGLFIKDGPVVQV
EEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCEEEE
RDAFNRIKVHEDPEADKSLYDGKIMVMINRHSASASEIFAAAMQDYNRAIIVGQQTFGKG
EHHHHHCCCCCCCCCCHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
TVQQSRSLNFVYDLDQEPLGFIQYTIQKFYRIDGGSTQLKGVEADIKFPEIINAEKTGES
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHCCCCCCCCC
FEDNALPWDKIPAASYQEAGHARDAVSALTAKHEERIAKEPEFITLNEDIAIRKERDARK
CCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEECCHHHHHH
YSSLNLEERLKEDRADEAKRLKDLNARFAREGKKAIKNIDALPKDYEAPDFFLKEAEKMM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VDWLEIDKKS
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]