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The map label for this gene is putA [H]

Identifier: 126175655

GI number: 126175655

Start: 4053970

End: 4057164

Strand: Direct

Name: putA [H]

Synonym: Sbal_3458

Alternate gene names: 126175655

Gene position: 4053970-4057164 (Clockwise)

Preceding gene: 126175654

Following gene: 126175656

Centisome position: 79.07

GC content: 50.17

Gene sequence:

>3195_bases
ATGGAAGCGATAACTATGTTCAAAGCGAGTGAAGTGCTGGCAGGCCGCTACGATTCTGCCAATCTCGACGAACTGTTCAA
AGCGATCAGCGACAACTACATTGTCGATGAAGAACAATACTTGTCAGAGTTGATCCAACTAGTTCCCTCCAGTGATGAAG
CCATAGAGCGCGTCACTCGTCGTGCCCACGAACTGGTTAACAAGGTTCGTCAATTCGATAAAAAAGGTTTGATGGTTGGC
ATAGATGCCTTCCTGCAACAGTACAGCTTAGAAACACAGGAAGGCATTATCCTGATGTGTTTAGCCGAAGCGCTGCTGCG
TATTCCTGATGCGGCCACTGCCGATGCACTGATTGAAGACAAGCTTTCAGGCGCTAAGTGGGATGAGCACATGAGTAAGA
GTGATTCTGTACTCGTTAACGCATCGACCTGGGGCCTTATGCTCACGGGTAAAATTGTCAAGCTCGATAAAAAAATCGAT
GGCACCCCAAGCAACTTACTGAGCCGCTTAGTTAATCGTCTCGGCGAGCCAGTGATCCGCCAAGCAATGATGGCCGCGAT
GAAGATCATGGGTAAGCAGTTTGTGCTGGGCCGCAACATGAAAGAAGCCCTGAAGAACAGTGAAGACAAGCGTAAGTTAG
GCTATACCCATTCCTACGACATGCTGGGCGAAGCGGCGTTAACGCGTAAAGATGCTGAGAAATACTATACCGATTACGCC
AATGCGATCACTGAGCTCGGTGCTCAAAGCTATAACGAAAATGAATCACCGCGCCCAACGATTTCAATCAAGCTATCGGC
ATTGCACCCACGTTACGAAGTGGCCAATGAAGACCGCGTTTTAACTGAACTGTACGACACAGTTATCCGCCTGATTACAC
TGGCTCGCGGCTTAAATATCGGTATTTCTATCGATGCTGAAGAAGTCGATCGCCTCGAGTTGTCACTGAAACTGTTCCAA
AAACTATTTAATTCAGAAGCGGCAAAAGGCTGGGGATTACTCGGTATTGTGGTTCAAGCTTACTCTAAGCGTGCCCTGCC
CGTACTGGTTTGGTTAACTCGCCTTGCGAAAGAGCAAGGGGATGAAATCCCCTTGCGTCTGGTAAAAGGCGCCTATTGGG
ATAGCGAACTGAAATGGGCCCAACAAGCTGGCGAAGCCGCTTACCCACTTTACACTCGCAAAGCCGGTACTGACGTTTCT
TACCTCGCCTGCGCCCGCTACTTGTTATCGGATGCGACTCGCGGCGCTATCTACCCACAATTTGCTAGCCACAATGCGCA
AACCGTTGCGGCGATTTCAGATATGGCGGGAGATCGTCACCATGAGTTCCAACGCTTACACGGCATGGGACAAGAGCTGT
ACGACACGATTTTGTCGGAAGCTGGCGCCAAATCGGTACGTATTTATGCGCCCATCGGTGCCCATAAGGATCTACTGCCC
TACTTAGTGCGTCGTCTGCTGGAAAACGGGGCCAACACTTCGTTCGTCCACAAGCTCGTTGATCCTAAAACCCCAATCGA
CTCATTAGTGGTGCATCCGCTAAAAACGCTGACGGGCTATAAAACCCTGGCTAACAATAGAATCGTTTTACCTGCCGATA
TTTTCGGTAGTGATCGCAAAAATTCCAAGGGACTCAATATGAACATCATTTCCGAATCTGAGCCATTTTTCGCGGCAATA
GAACAGTTTAAAAATACCCAATGGCAAGCAGGCCCTCTGGTTAACGGCAAAACCTTAACCGGTGAGCACAAAACCATAGT
CAGCCCATACGACACCACCCAAACAGTGGGTCAAGTAGCCTTTGCCGATGATGCGGCCATAGAACAAGCACTCGCGTCTG
CTGAAGCGGCGTTTGCCTCATGGGCACGTACGCCGGTTGAAACCCGTGCCTCTGCGCTGCAAAAACTCGCTGACTTATTA
GAAGAAAACCGCGAAGAATTGATCGCCTTGTGTACCCGTGAAGCGGGCAAGAGCATTCAAGACGGTATCGACGAAGTACG
TGAAGCCGTTGATTTCTGTCGTTACTACGCAGTACAAGCCAAGAAAATGATGGCGAAGCCTGAACTGCTTCCTGGCCCAA
CAGGAGAGCTGAACGAACTGTTCCTCCAAGGCCGCGGCGTATTCGTGTGTATTAGCCCGTGGAACTTCCCATTGGCCATC
TTCCTCGGCCAAGTGTCTGCGGCATTAGCGGCAGGTAACACAGTGATCGCGAAACCTGCGGAGCAAACCTCGATTATTGG
TTACCGTGCAGTACAACTTGCTCACCAAGCAGGTATTCCTGTTGAGGTTCTGCAATTCCTACCAGGTACGGGTGCGACTG
TGGGTAGCGCAATTACAGCCGATGAACGTATCGGCGGCGTATGCTTTACCGGTTCAACTGGCACTGCAAAACTGATTAAC
CGTACACTGGCCAACCGTGATGGCGCGATTATTCCTTTAATCGCCGAAACTGGTGGTCAAAATGCCATGGTAGTGGACTC
AACCTCACAACCTGAGCAAGTGGTTAACGATGTGGTTTCATCGTCATTCACCAGCGCGGGTCAACGCTGTTCAGCATTGC
GCGTACTCTTCCTACAAGAAGACATCGCCGATCGCGTGATCGAAGTGCTGCAAGGCGCGATGGATGAATTAGTGATTGGC
AACCCAAGCTCAGTGAAAACTGACGTAGGCCCAGTGATTGACGCCACCGCCAAAGCCAACTTAGATGCGCACATCGACCA
CATAAAGCAAGTCGGCAAGCTTATTAAGCAAATGCCGTTGCCTGCTGGTACAGAGAACGGTCACTTCGTTTCACCCACTG
CGGTTGAAATCGATTCGATTAAAGTGCTTGAGAAAGAACACTTTGGCCCAATCCTGCACATTATTCGCTACAACGCTGCA
GAGCTAAGCCAAGTGATCAACGAGATCAATAGCACAGGCTTTGGCTTAACCTTAGGCATCCACAGCCGTAACGAAGGCCA
TGCCCTTGAGGTTGCAGATAAAGTCAACGTGGGTAACGTGTACATTAACCGTAACCAAATCGGCGCTGTGGTGGGTGTAC
AGCCTTTCGGCGGTCAAGGCCTGTCAGGCACTGGTCCTAAAGCCGGTGGCCCACACTACTTAACCCGTTTTGTGACTGAA
AAGACTCGCACCAACAACATCACCGCCATAGGTGGTAATGCAACGTTATTGTCACTGGGTGATGGCGAAGAATAA

Upstream 100 bases:

>100_bases
TATAATCGGCGCGCGCAAACCTTCATATTGTATACAAAATATCAAATGCGTTTGGCGCCTCCCAATTTGTTTCAACAATA
GCGCCCCAATAACGGCCAAG

Downstream 100 bases:

>100_bases
TATCGCTCGCCAGTAAACATAAAAAAGCCAGACTGAGTCTGGCTTTTTTATTGGCTGCGGTTTATCTCTGACAAAGATAA
GTAGTCCTAAACCTCAGGAT

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1064; Mature: 1064

Protein sequence:

>1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAISDNYIVDEEQYLSELIQLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHMSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRNMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYYTDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLITLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNSEAAKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPLRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRHHEFQRLHGMGQELYDTILSEAGAKSVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIDSLVVHPLKTLTGYKTLANNRIVLPADIFGSDRKNSKGLNMNIISESEPFFAAI
EQFKNTQWQAGPLVNGKTLTGEHKTIVSPYDTTQTVGQVAFADDAAIEQALASAEAAFASWARTPVETRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVIAKPAEQTSIIGYRAVQLAHQAGIPVEVLQFLPGTGATVGSAITADERIGGVCFTGSTGTAKLIN
RTLANRDGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIEVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMPLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHIIRYNAA
ELSQVINEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDGEE

Sequences:

>Translated_1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAISDNYIVDEEQYLSELIQLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHMSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRNMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYYTDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLITLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNSEAAKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPLRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRHHEFQRLHGMGQELYDTILSEAGAKSVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIDSLVVHPLKTLTGYKTLANNRIVLPADIFGSDRKNSKGLNMNIISESEPFFAAI
EQFKNTQWQAGPLVNGKTLTGEHKTIVSPYDTTQTVGQVAFADDAAIEQALASAEAAFASWARTPVETRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVIAKPAEQTSIIGYRAVQLAHQAGIPVEVLQFLPGTGATVGSAITADERIGGVCFTGSTGTAKLIN
RTLANRDGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIEVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMPLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHIIRYNAA
ELSQVINEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDGEE
>Mature_1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAISDNYIVDEEQYLSELIQLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHMSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRNMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYYTDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLITLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNSEAAKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPLRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRHHEFQRLHGMGQELYDTILSEAGAKSVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIDSLVVHPLKTLTGYKTLANNRIVLPADIFGSDRKNSKGLNMNIISESEPFFAAI
EQFKNTQWQAGPLVNGKTLTGEHKTIVSPYDTTQTVGQVAFADDAAIEQALASAEAAFASWARTPVETRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVIAKPAEQTSIIGYRAVQLAHQAGIPVEVLQFLPGTGATVGSAITADERIGGVCFTGSTGTAKLIN
RTLANRDGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIEVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMPLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHIIRYNAA
ELSQVINEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDGEE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=488, Percent_Identity=30.1229508196721, Blast_Score=203, Evalue=7e-52,
Organism=Homo sapiens, GI25777734, Length=488, Percent_Identity=30.1229508196721, Blast_Score=203, Evalue=7e-52,
Organism=Homo sapiens, GI238859541, Length=488, Percent_Identity=30.1229508196721, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI153266822, Length=490, Percent_Identity=29.5918367346939, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777732, Length=479, Percent_Identity=31.3152400835073, Blast_Score=190, Evalue=5e-48,
Organism=Homo sapiens, GI21361176, Length=498, Percent_Identity=28.9156626506024, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI25777730, Length=478, Percent_Identity=30.5439330543933, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI25777724, Length=479, Percent_Identity=29.6450939457203, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI21614513, Length=434, Percent_Identity=30.4147465437788, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI12007648, Length=483, Percent_Identity=28.5714285714286, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI238814322, Length=479, Percent_Identity=29.4363256784969, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI25777728, Length=410, Percent_Identity=30, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI4507229, Length=475, Percent_Identity=28.2105263157895, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI188035924, Length=481, Percent_Identity=27.4428274428274, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI310128093, Length=462, Percent_Identity=27.9220779220779, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI310128103, Length=462, Percent_Identity=27.9220779220779, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI25777721, Length=488, Percent_Identity=27.2540983606557, Blast_Score=144, Evalue=7e-34,
Organism=Homo sapiens, GI25952152, Length=474, Percent_Identity=27.2151898734177, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI115387104, Length=445, Percent_Identity=25.1685393258427, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI11095441, Length=420, Percent_Identity=28.3333333333333, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI25777726, Length=479, Percent_Identity=26.7223382045929, Blast_Score=133, Evalue=7e-31,
Organism=Homo sapiens, GI310128091, Length=416, Percent_Identity=27.4038461538462, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI206597441, Length=443, Percent_Identity=24.6049661399549, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI206597439, Length=443, Percent_Identity=24.6049661399549, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI22907049, Length=443, Percent_Identity=24.6049661399549, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI4502043, Length=420, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI238814371, Length=420, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI310128087, Length=282, Percent_Identity=28.7234042553192, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI71773324, Length=416, Percent_Identity=25.2403846153846, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI301500698, Length=283, Percent_Identity=27.5618374558304, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI4557303, Length=435, Percent_Identity=22.9885057471264, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI73466520, Length=435, Percent_Identity=22.9885057471264, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI310128089, Length=328, Percent_Identity=27.4390243902439, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI73695881, Length=327, Percent_Identity=25.3822629969419, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI73695879, Length=327, Percent_Identity=25.3822629969419, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI310128099, Length=232, Percent_Identity=28.8793103448276, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI310128101, Length=230, Percent_Identity=28.695652173913, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128095, Length=314, Percent_Identity=26.7515923566879, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128097, Length=261, Percent_Identity=27.9693486590038, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI223972651, Length=497, Percent_Identity=24.9496981891348, Blast_Score=78, Evalue=6e-14,
Organism=Escherichia coli, GI1787250, Length=1044, Percent_Identity=47.0306513409962, Blast_Score=900, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=504, Percent_Identity=31.547619047619, Blast_Score=213, Evalue=6e-56,
Organism=Escherichia coli, GI1787715, Length=471, Percent_Identity=30.9978768577495, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI1789015, Length=474, Percent_Identity=29.746835443038, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1787558, Length=481, Percent_Identity=29.5218295218295, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI1788042, Length=460, Percent_Identity=30.4347826086957, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1787684, Length=439, Percent_Identity=28.4738041002278, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI87082295, Length=457, Percent_Identity=28.0087527352298, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1786504, Length=438, Percent_Identity=26.4840182648402, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081926, Length=432, Percent_Identity=28.7037037037037, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1787653, Length=372, Percent_Identity=24.1935483870968, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=476, Percent_Identity=31.9327731092437, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI133930964, Length=503, Percent_Identity=28.2306163021869, Blast_Score=175, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI25144435, Length=490, Percent_Identity=29.5918367346939, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=397, Percent_Identity=32.2418136020151, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=458, Percent_Identity=29.6943231441048, Blast_Score=172, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17551164, Length=454, Percent_Identity=30.1762114537445, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=30.6372549019608, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI32564151, Length=428, Percent_Identity=29.6728971962617, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=463, Percent_Identity=28.5097192224622, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995606, Length=465, Percent_Identity=27.0967741935484, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=435, Percent_Identity=26.8965517241379, Blast_Score=143, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17534119, Length=481, Percent_Identity=26.4033264033264, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=421, Percent_Identity=28.7410926365796, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=435, Percent_Identity=26.8965517241379, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=26.1282660332542, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=308, Percent_Identity=31.1688311688312, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=460, Percent_Identity=24.1304347826087, Blast_Score=103, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=460, Percent_Identity=24.1304347826087, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI32566756, Length=460, Percent_Identity=24.1304347826087, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17564084, Length=468, Percent_Identity=24.7863247863248, Blast_Score=102, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324950, Length=465, Percent_Identity=28.8172043010753, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6320917, Length=468, Percent_Identity=29.2735042735043, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=519, Percent_Identity=28.7090558766859, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323821, Length=469, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6323822, Length=484, Percent_Identity=28.5123966942149, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=448, Percent_Identity=29.4642857142857, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=489, Percent_Identity=26.9938650306748, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321828, Length=481, Percent_Identity=24.3243243243243, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6323757, Length=410, Percent_Identity=22.9268292682927, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24668425, Length=487, Percent_Identity=31.006160164271, Blast_Score=196, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24668417, Length=487, Percent_Identity=31.006160164271, Blast_Score=196, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24668413, Length=487, Percent_Identity=31.006160164271, Blast_Score=196, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24585660, Length=475, Percent_Identity=28, Blast_Score=183, Evalue=6e-46,
Organism=Drosophila melanogaster, GI20129399, Length=492, Percent_Identity=29.2682926829268, Blast_Score=179, Evalue=8e-45,
Organism=Drosophila melanogaster, GI281362580, Length=455, Percent_Identity=28.7912087912088, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI62472918, Length=455, Percent_Identity=28.7912087912088, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI62472926, Length=455, Percent_Identity=28.7912087912088, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI62472936, Length=455, Percent_Identity=28.7912087912088, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356737, Length=455, Percent_Identity=28.7912087912088, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24650465, Length=443, Percent_Identity=28.8939051918736, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28571806, Length=484, Percent_Identity=26.6528925619835, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571802, Length=483, Percent_Identity=26.7080745341615, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571800, Length=483, Percent_Identity=26.7080745341615, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571798, Length=484, Percent_Identity=26.6528925619835, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571796, Length=484, Percent_Identity=26.6528925619835, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571794, Length=484, Percent_Identity=26.6528925619835, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24666674, Length=456, Percent_Identity=28.0701754385965, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574525, Length=497, Percent_Identity=23.5412474849095, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24638878, Length=439, Percent_Identity=27.5626423690205, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24638876, Length=439, Percent_Identity=27.5626423690205, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI45552499, Length=453, Percent_Identity=24.5033112582781, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281360303, Length=453, Percent_Identity=24.5033112582781, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360299, Length=457, Percent_Identity=24.2888402625821, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360297, Length=457, Percent_Identity=24.2888402625821, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360295, Length=457, Percent_Identity=24.2888402625821, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586250, Length=457, Percent_Identity=24.2888402625821, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360301, Length=457, Percent_Identity=24.2888402625821, Blast_Score=91, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 115780; Mature: 115780

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAITMFKASEVLAGRYDSANLDELFKAISDNYIVDEEQYLSELIQLVPSSDEAIERVTR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCHHHHHHHHH
RAHELVNKVRQFDKKGLMVGIDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHMSKSDSVLVNASTWGLMLTGKIVKLDKKIDGTPSNLLSRLVNRLGEPVIR
HCCCCCHHHHCCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QAMMAAMKIMGKQFVLGRNMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYYTDYA
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLITLARGLNI
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEVDRLELSLKLFQKLFNSEAAKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DEIPLRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTVAAISDMAGDRHHEFQRLHGMGQELYDTILSEAGAKSVRIYAPIGAHKDLLP
HHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
YLVRRLLENGANTSFVHKLVDPKTPIDSLVVHPLKTLTGYKTLANNRIVLPADIFGSDRK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCC
NSKGLNMNIISESEPFFAAIEQFKNTQWQAGPLVNGKTLTGEHKTIVSPYDTTQTVGQVA
CCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHH
FADDAAIEQALASAEAAFASWARTPVETRASALQKLADLLEENREELIALCTREAGKSIQ
HCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHH
FLGQVSAALAAGNTVIAKPAEQTSIIGYRAVQLAHQAGIPVEVLQFLPGTGATVGSAITA
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
DERIGGVCFTGSTGTAKLINRTLANRDGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQEDIADRVIEVLQGAMDELVIGNPSSVKTDVGPVIDATAKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCHHHCC
LDAHIDHIKQVGKLIKQMPLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHIIRYNAA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEECHHHHHHHHHCCHHHHHHHCCHH
ELSQVINEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCCC
LSGTGPKAGGPHYLTRFVTEKTRTNNITAIGGNATLLSLGDGEE
CCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCC
>Mature Secondary Structure
MEAITMFKASEVLAGRYDSANLDELFKAISDNYIVDEEQYLSELIQLVPSSDEAIERVTR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCHHHHHHHHH
RAHELVNKVRQFDKKGLMVGIDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHMSKSDSVLVNASTWGLMLTGKIVKLDKKIDGTPSNLLSRLVNRLGEPVIR
HCCCCCHHHHCCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QAMMAAMKIMGKQFVLGRNMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYYTDYA
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLITLARGLNI
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEVDRLELSLKLFQKLFNSEAAKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DEIPLRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTVAAISDMAGDRHHEFQRLHGMGQELYDTILSEAGAKSVRIYAPIGAHKDLLP
HHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
YLVRRLLENGANTSFVHKLVDPKTPIDSLVVHPLKTLTGYKTLANNRIVLPADIFGSDRK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCC
NSKGLNMNIISESEPFFAAIEQFKNTQWQAGPLVNGKTLTGEHKTIVSPYDTTQTVGQVA
CCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHH
FADDAAIEQALASAEAAFASWARTPVETRASALQKLADLLEENREELIALCTREAGKSIQ
HCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHH
FLGQVSAALAAGNTVIAKPAEQTSIIGYRAVQLAHQAGIPVEVLQFLPGTGATVGSAITA
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
DERIGGVCFTGSTGTAKLINRTLANRDGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQEDIADRVIEVLQGAMDELVIGNPSSVKTDVGPVIDATAKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCHHHCC
LDAHIDHIKQVGKLIKQMPLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHIIRYNAA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEECHHHHHHHHHCCHHHHHHHCCHH
ELSQVINEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCCC
LSGTGPKAGGPHYLTRFVTEKTRTNNITAIGGNATLLSLGDGEE
CCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]