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The map label for this gene is gldA [H]

Identifier: 126175553

GI number: 126175553

Start: 3920787

End: 3921902

Strand: Direct

Name: gldA [H]

Synonym: Sbal_3356

Alternate gene names: 126175553

Gene position: 3920787-3921902 (Clockwise)

Preceding gene: 126175549

Following gene: 126175554

Centisome position: 76.47

GC content: 50.9

Gene sequence:

>1116_bases
ATGAGCACTGTCGTTCCACGTACCGTCACTTCCCCTAAAAAGTTCATTATCGGCAAGGGCTTATTAGCTCAAATGCATGA
TTATGTTAAGGACTTTGGTGACAATGCTTTTATCATCTGCGATGAATTTATCCTCAGCCGAGTTGAGAATGAAGCGGTCG
CAGGGCTGGATCAAAATGGGATCAGCAGCCATCTCGAAAAATTCAACTATGAGTGCAGCGAAGCCGAGATAAAGCGCTTA
GGTGCGCTGGCAGAGCAGCATCATACCAACGTGATTGTAGGGATCGGCGGGGGTAAAACCTTAGATACCGCCAAAGCCGT
CGCCTTCTATCAAAAACGGCCAGTGGTGCTCTACCCAACCATTGCTTCAACCGATGCACCATGTACGGCACTTGCCGTGA
TCTATTCCGAAACCGGTGAGTTTGAGCACTATCTGTTTCTGCCACAAAATCCTGATGCTGTTGTTGCCGACACAGCCATT
ATCGCCGCGGCTCCCGCCCGATTCTTTGCAGCAGGCATAGGCGATGCACTGGCCACTTACTTTGAAGCCCGCGCCTGTTA
TCAATCCGATGGCGTCAATCTCGTATTGAAAAAACCTTCCCGCACTGGGCTGGGATTAGCGCAGCTTTGCTATCAGTTAC
TGACTGAAAATGTTGAAGCCGCTATGGATGCGGTGAGAAACAAGATAGTCACTCCCGCACTTGAGCAAACCATTGAAGCG
ACGATTTATCTCAGTGGTGTCGGGGCCGAAGCGGGCGGATTAGCCGCAGCCCATGCTGTGAACAATGGTATGTCGGCGGT
AGCTGACCTACATAAAGCCCAGCACGGCGAGAAAGTGGTGTTTGGCTTGCTCACCCAGCTAGTACTCGAAAATGCCCCCA
AAACCGAAATTGATAACGTCATTCACATCATCAAAACCGCGGGACTGCCGCTCACGCTCGCCGATTTGGGGCTAAAAACC
TTTGTCGAAGCAGAGTGGCGCAAAGTGGCTGAGATAGCCTGCGCTGAAGGCGACACTATGGGTAATATGCCGATGCAGTT
AACTGCCGACGATGTCTATCAAGCCATGATCGCCGCCAATGCCATGGCTGAGCGCTATAAAACGCTTGCGATTTAA

Upstream 100 bases:

>100_bases
CATAATAAAAATATTACCACCGCTCATGCTGTGACGACAAATTAAGCGTATGCTAGGGTAAGCATGAAAGGATAACCGTC
ATAAGTGCAAAGGAGGCTCT

Downstream 100 bases:

>100_bases
AACAATTAAAAACGCCTCTGGCAGGCGCCCATCATCCCCTTGATATTTTTATCAAAGGGATGATGAGCGCGGCTAAAACA
CAGCCTGCCACTGCGCGAGT

Product: glycerol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSTVVPRTVTSPKKFIIGKGLLAQMHDYVKDFGDNAFIICDEFILSRVENEAVAGLDQNGISSHLEKFNYECSEAEIKRL
GALAEQHHTNVIVGIGGGKTLDTAKAVAFYQKRPVVLYPTIASTDAPCTALAVIYSETGEFEHYLFLPQNPDAVVADTAI
IAAAPARFFAAGIGDALATYFEARACYQSDGVNLVLKKPSRTGLGLAQLCYQLLTENVEAAMDAVRNKIVTPALEQTIEA
TIYLSGVGAEAGGLAAAHAVNNGMSAVADLHKAQHGEKVVFGLLTQLVLENAPKTEIDNVIHIIKTAGLPLTLADLGLKT
FVEAEWRKVAEIACAEGDTMGNMPMQLTADDVYQAMIAANAMAERYKTLAI

Sequences:

>Translated_371_residues
MSTVVPRTVTSPKKFIIGKGLLAQMHDYVKDFGDNAFIICDEFILSRVENEAVAGLDQNGISSHLEKFNYECSEAEIKRL
GALAEQHHTNVIVGIGGGKTLDTAKAVAFYQKRPVVLYPTIASTDAPCTALAVIYSETGEFEHYLFLPQNPDAVVADTAI
IAAAPARFFAAGIGDALATYFEARACYQSDGVNLVLKKPSRTGLGLAQLCYQLLTENVEAAMDAVRNKIVTPALEQTIEA
TIYLSGVGAEAGGLAAAHAVNNGMSAVADLHKAQHGEKVVFGLLTQLVLENAPKTEIDNVIHIIKTAGLPLTLADLGLKT
FVEAEWRKVAEIACAEGDTMGNMPMQLTADDVYQAMIAANAMAERYKTLAI
>Mature_370_residues
STVVPRTVTSPKKFIIGKGLLAQMHDYVKDFGDNAFIICDEFILSRVENEAVAGLDQNGISSHLEKFNYECSEAEIKRLG
ALAEQHHTNVIVGIGGGKTLDTAKAVAFYQKRPVVLYPTIASTDAPCTALAVIYSETGEFEHYLFLPQNPDAVVADTAII
AAAPARFFAAGIGDALATYFEARACYQSDGVNLVLKKPSRTGLGLAQLCYQLLTENVEAAMDAVRNKIVTPALEQTIEAT
IYLSGVGAEAGGLAAAHAVNNGMSAVADLHKAQHGEKVVFGLLTQLVLENAPKTEIDNVIHIIKTAGLPLTLADLGLKTF
VEAEWRKVAEIACAEGDTMGNMPMQLTADDVYQAMIAANAMAERYKTLAI

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions [H]

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=360, Percent_Identity=50.5555555555556, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1786815, Length=360, Percent_Identity=30, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 39691; Mature: 39560

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00913 ADH_IRON_1 ; PS00687 ALDEHYDE_DEHYDR_GLU ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVVPRTVTSPKKFIIGKGLLAQMHDYVKDFGDNAFIICDEFILSRVENEAVAGLDQNG
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCHHHCCCCCCH
ISSHLEKFNYECSEAEIKRLGALAEQHHTNVIVGIGGGKTLDTAKAVAFYQKRPVVLYPT
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEC
IASTDAPCTALAVIYSETGEFEHYLFLPQNPDAVVADTAIIAAAPARFFAAGIGDALATY
CCCCCCCHHHEEEEECCCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
FEARACYQSDGVNLVLKKPSRTGLGLAQLCYQLLTENVEAAMDAVRNKIVTPALEQTIEA
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEE
TIYLSGVGAEAGGLAAAHAVNNGMSAVADLHKAQHGEKVVFGLLTQLVLENAPKTEIDNV
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
IHIIKTAGLPLTLADLGLKTFVEAEWRKVAEIACAEGDTMGNMPMQLTADDVYQAMIAAN
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHH
AMAERYKTLAI
HHHHHHHHHCC
>Mature Secondary Structure 
STVVPRTVTSPKKFIIGKGLLAQMHDYVKDFGDNAFIICDEFILSRVENEAVAGLDQNG
CCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCHHHCCCCCCH
ISSHLEKFNYECSEAEIKRLGALAEQHHTNVIVGIGGGKTLDTAKAVAFYQKRPVVLYPT
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEC
IASTDAPCTALAVIYSETGEFEHYLFLPQNPDAVVADTAIIAAAPARFFAAGIGDALATY
CCCCCCCHHHEEEEECCCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
FEARACYQSDGVNLVLKKPSRTGLGLAQLCYQLLTENVEAAMDAVRNKIVTPALEQTIEA
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEE
TIYLSGVGAEAGGLAAAHAVNNGMSAVADLHKAQHGEKVVFGLLTQLVLENAPKTEIDNV
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
IHIIKTAGLPLTLADLGLKTFVEAEWRKVAEIACAEGDTMGNMPMQLTADDVYQAMIAAN
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHH
AMAERYKTLAI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]