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The map label for this gene is dxs [H]

Identifier: 126175163

GI number: 126175163

Start: 3473103

End: 3474878

Strand: Reverse

Name: dxs [H]

Synonym: Sbal_2961

Alternate gene names: 126175163

Gene position: 3474878-3473103 (Counterclockwise)

Preceding gene: 126175164

Following gene: 126175162

Centisome position: 67.77

GC content: 41.1

Gene sequence:

>1776_bases
ATGGAAATCATTGATTATATTGATTTTGCAGGCTCTCCAGCTGAACTTAAAAAATTACCAATTGAAGCTCTGGATGGACA
GGCCGAAAAAATACGTTGTTTTTTGATAGATAAAATATCTGCCACCGGTGGTCATATTGGTGCCAACCTTTCAGTGATTG
AGCTAACCTTGGCGATTCATTTTGTTTTTAATTCTCCTTTTGACAAAATTATTTTTGATACTGGTCACCAAGGATACACC
CATAAGCTTTTAACTGGGCGCCGTGCCGCATTTGACTCTCTTAACACTTATAAGGGGATGAGTCGTTTTATCGCTAGAGA
AGAAAGTGAGCACGATACTATCGACGCTTCCCACGCTGGTACATCAATTTCATTGGCGACAGGTATCTCTGCTGCGCTCA
AAACCAAAGGAAGTAGTGACTTTACAGTTTCAGTCATCGGAGATGGTTCTCTGGTTGAAGGTATGGCATTTGAGGCTCTA
AACTTTGGAAGTGTAGATAAGGATGCCAAGCTTATTCTTGTAGTTAATGATAACGAAATGGCAATAGCGCCGTCAGTAGG
CGGTGTTAGACAACTCACTATTGGTGATAATTGGCAAGAAAAATCCCAACACTTTTTTGAAAGTTTAGGTTACGGCTATT
TTTCTGTTGCAAATGGTCACTGCACAAAGTCTCTTGTTCAGGCTCTTAAGAATGCAAAGACTCTTGGGCGCCCTACAGTA
GTGCATATCAAAACTCTAAAAGGAAAGGGGTTAGATTACGCAGGTTCTCATCCCTATAAAATGCATTTTTCAATGCCTTT
TAATCCAATCACTGGTGAAGGTGCGTCACCTACAGTTGCTGGAAAGACTTTTGCGGTTGTTTTTGCTGAAAAATTAGCTG
CACTTATGGCATCGGATCCTGATATTCATGTTATCACTCCTGCAACACCCTATGCTTCGTCTTTGGATGGTTTATTTGCC
TTGTTCCCAGGTCGAGTCATAGATGTTGGAATGGCGGAGCAACACGCTGTTGGAATGGCTTGTGGCATGGCCCTTGAGGG
ATTAAAGCCTGTAGTATGTATGCAAACTACCTTTATGCAAAGGGCCTTCGATCAGTTGTTGCATGATGCTTGTTATATGA
ATTTACCCATCACTGTACTGGGTGTCAGGGCTGGATTTGCGGGATACGATGGCTCTACTCATCATGGGATTTATGATATT
CCGTATTTAAAATCATTCCCGAATATGCAAGTGGAATATCCGATTAATAGTATCGAGGCGCAGAGATTGTTGGAAAGGCG
TTTAGTTTCGCCTGTTGGTCCTATGGTTATTTTGCATCCCTATGAGCCCTTAAGTACTTCAGAGCCTGATACTGGAGTTC
TTAGCAAGGGGATGTCTATCGCCGCCAAAGGTAAAAATGGTTTTATTATTTGTCTTGGAAATACTTTGGCAAAGGCTTGG
GAACTCAAATCACTATTGGCAAATTTAGGTAAAACGTTTGGTATTATTTGTGTTCAGAGCATCAAACCTTTTCCTGTAAA
TGGCATTCTCGATTTATTGGTTTCTGGAATGGACATTATCACCCTTGAGGAGAGCGTATTAGCAGGGGGCTTTGGTTCAG
TATTACTTGAGACCATAAGTGATTCAGATATTAATCTCAGGGTTTTTAGAAGTGGTGTAGAAGATAGTTTTATAAGGCCA
GGAAGTAAGCAAGAATGTAGTGATGAAGCTGGTATTACTGCAAAACAGATAGTGGTGAAAATCCAGCGGCGTTGGATGGA
ATATCAAGAGGAATAA

Upstream 100 bases:

>100_bases
TGGTATTAAGGCTGGCATTATACACGATGATGCTGATCCCTATGGTACCAATACTGTTCTTGTTTGTATAAAACCTATTC
GTTAATTTTTAAGGATTTTT

Downstream 100 bases:

>100_bases
CTAGTGGGTAGACTCACAGGTAAAGTGGCGCTTATCACTGGTGCATCAAGAGGGATCGGTGCTGGTATTGCTGAAGCTTT
TGCCATCGAAGGTGCTGATT

Product: transketolase, central region

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MEIIDYIDFAGSPAELKKLPIEALDGQAEKIRCFLIDKISATGGHIGANLSVIELTLAIHFVFNSPFDKIIFDTGHQGYT
HKLLTGRRAAFDSLNTYKGMSRFIAREESEHDTIDASHAGTSISLATGISAALKTKGSSDFTVSVIGDGSLVEGMAFEAL
NFGSVDKDAKLILVVNDNEMAIAPSVGGVRQLTIGDNWQEKSQHFFESLGYGYFSVANGHCTKSLVQALKNAKTLGRPTV
VHIKTLKGKGLDYAGSHPYKMHFSMPFNPITGEGASPTVAGKTFAVVFAEKLAALMASDPDIHVITPATPYASSLDGLFA
LFPGRVIDVGMAEQHAVGMACGMALEGLKPVVCMQTTFMQRAFDQLLHDACYMNLPITVLGVRAGFAGYDGSTHHGIYDI
PYLKSFPNMQVEYPINSIEAQRLLERRLVSPVGPMVILHPYEPLSTSEPDTGVLSKGMSIAAKGKNGFIICLGNTLAKAW
ELKSLLANLGKTFGIICVQSIKPFPVNGILDLLVSGMDIITLEESVLAGGFGSVLLETISDSDINLRVFRSGVEDSFIRP
GSKQECSDEAGITAKQIVVKIQRRWMEYQEE

Sequences:

>Translated_591_residues
MEIIDYIDFAGSPAELKKLPIEALDGQAEKIRCFLIDKISATGGHIGANLSVIELTLAIHFVFNSPFDKIIFDTGHQGYT
HKLLTGRRAAFDSLNTYKGMSRFIAREESEHDTIDASHAGTSISLATGISAALKTKGSSDFTVSVIGDGSLVEGMAFEAL
NFGSVDKDAKLILVVNDNEMAIAPSVGGVRQLTIGDNWQEKSQHFFESLGYGYFSVANGHCTKSLVQALKNAKTLGRPTV
VHIKTLKGKGLDYAGSHPYKMHFSMPFNPITGEGASPTVAGKTFAVVFAEKLAALMASDPDIHVITPATPYASSLDGLFA
LFPGRVIDVGMAEQHAVGMACGMALEGLKPVVCMQTTFMQRAFDQLLHDACYMNLPITVLGVRAGFAGYDGSTHHGIYDI
PYLKSFPNMQVEYPINSIEAQRLLERRLVSPVGPMVILHPYEPLSTSEPDTGVLSKGMSIAAKGKNGFIICLGNTLAKAW
ELKSLLANLGKTFGIICVQSIKPFPVNGILDLLVSGMDIITLEESVLAGGFGSVLLETISDSDINLRVFRSGVEDSFIRP
GSKQECSDEAGITAKQIVVKIQRRWMEYQEE
>Mature_591_residues
MEIIDYIDFAGSPAELKKLPIEALDGQAEKIRCFLIDKISATGGHIGANLSVIELTLAIHFVFNSPFDKIIFDTGHQGYT
HKLLTGRRAAFDSLNTYKGMSRFIAREESEHDTIDASHAGTSISLATGISAALKTKGSSDFTVSVIGDGSLVEGMAFEAL
NFGSVDKDAKLILVVNDNEMAIAPSVGGVRQLTIGDNWQEKSQHFFESLGYGYFSVANGHCTKSLVQALKNAKTLGRPTV
VHIKTLKGKGLDYAGSHPYKMHFSMPFNPITGEGASPTVAGKTFAVVFAEKLAALMASDPDIHVITPATPYASSLDGLFA
LFPGRVIDVGMAEQHAVGMACGMALEGLKPVVCMQTTFMQRAFDQLLHDACYMNLPITVLGVRAGFAGYDGSTHHGIYDI
PYLKSFPNMQVEYPINSIEAQRLLERRLVSPVGPMVILHPYEPLSTSEPDTGVLSKGMSIAAKGKNGFIICLGNTLAKAW
ELKSLLANLGKTFGIICVQSIKPFPVNGILDLLVSGMDIITLEESVLAGGFGSVLLETISDSDINLRVFRSGVEDSFIRP
GSKQECSDEAGITAKQIVVKIQRRWMEYQEE

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786622, Length=618, Percent_Identity=32.5242718446602, Blast_Score=326, Evalue=3e-90,
Organism=Drosophila melanogaster, GI45551847, Length=632, Percent_Identity=22.7848101265823, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550715, Length=632, Percent_Identity=22.7848101265823, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645119, Length=518, Percent_Identity=23.1660231660232, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 63812; Mature: 63812

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIDYIDFAGSPAELKKLPIEALDGQAEKIRCFLIDKISATGGHIGANLSVIELTLAIH
CCHHHHHCCCCCHHHHHHCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEE
FVFNSPFDKIIFDTGHQGYTHKLLTGRRAAFDSLNTYKGMSRFIAREESEHDTIDASHAG
EEECCCCHHHEEECCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TSISLATGISAALKTKGSSDFTVSVIGDGSLVEGMAFEALNFGSVDKDAKLILVVNDNEM
CEEEHHHCCHHHHHCCCCCCEEEEEECCCCHHCCHHHHHCCCCCCCCCCEEEEEECCCCE
AIAPSVGGVRQLTIGDNWQEKSQHFFESLGYGYFSVANGHCTKSLVQALKNAKTLGRPTV
EEECCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCEE
VHIKTLKGKGLDYAGSHPYKMHFSMPFNPITGEGASPTVAGKTFAVVFAEKLAALMASDP
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
DIHVITPATPYASSLDGLFALFPGRVIDVGMAEQHAVGMACGMALEGLKPVVCMQTTFMQ
CEEEECCCCCCCHHHCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAFDQLLHDACYMNLPITVLGVRAGFAGYDGSTHHGIYDIPYLKSFPNMQVEYPINSIEA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEECCHHHCCCCCEEECCCCHHHH
QRLLERRLVSPVGPMVILHPYEPLSTSEPDTGVLSKGMSIAAKGKNGFIICLGNTLAKAW
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEECCHHHHHH
ELKSLLANLGKTFGIICVQSIKPFPVNGILDLLVSGMDIITLEESVLAGGFGSVLLETIS
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECHHHHCCCHHHHHHHHHC
DSDINLRVFRSGVEDSFIRPGSKQECSDEAGITAKQIVVKIQRRWMEYQEE
CCCCEEEEEECCCCHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIIDYIDFAGSPAELKKLPIEALDGQAEKIRCFLIDKISATGGHIGANLSVIELTLAIH
CCHHHHHCCCCCHHHHHHCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEE
FVFNSPFDKIIFDTGHQGYTHKLLTGRRAAFDSLNTYKGMSRFIAREESEHDTIDASHAG
EEECCCCHHHEEECCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TSISLATGISAALKTKGSSDFTVSVIGDGSLVEGMAFEALNFGSVDKDAKLILVVNDNEM
CEEEHHHCCHHHHHCCCCCCEEEEEECCCCHHCCHHHHHCCCCCCCCCCEEEEEECCCCE
AIAPSVGGVRQLTIGDNWQEKSQHFFESLGYGYFSVANGHCTKSLVQALKNAKTLGRPTV
EEECCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCEE
VHIKTLKGKGLDYAGSHPYKMHFSMPFNPITGEGASPTVAGKTFAVVFAEKLAALMASDP
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
DIHVITPATPYASSLDGLFALFPGRVIDVGMAEQHAVGMACGMALEGLKPVVCMQTTFMQ
CEEEECCCCCCCHHHCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAFDQLLHDACYMNLPITVLGVRAGFAGYDGSTHHGIYDIPYLKSFPNMQVEYPINSIEA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEECCHHHCCCCCEEECCCCHHHH
QRLLERRLVSPVGPMVILHPYEPLSTSEPDTGVLSKGMSIAAKGKNGFIICLGNTLAKAW
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEECCHHHHHH
ELKSLLANLGKTFGIICVQSIKPFPVNGILDLLVSGMDIITLEESVLAGGFGSVLLETIS
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECHHHHCCCHHHHHHHHHC
DSDINLRVFRSGVEDSFIRPGSKQECSDEAGITAKQIVVKIQRRWMEYQEE
CCCCEEEEEECCCCHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA