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The map label for this gene is efp

Identifier: 126174448

GI number: 126174448

Start: 2579789

End: 2580349

Strand: Direct

Name: efp

Synonym: Sbal_2232

Alternate gene names: 126174448

Gene position: 2579789-2580349 (Clockwise)

Preceding gene: 126174447

Following gene: 126174451

Centisome position: 50.31

GC content: 42.78

Gene sequence:

>561_bases
ATGAAAACTGCTCATGAAATCCGTCCTGGTAACGTGATCATGTTAGATGGCAGCCCATGGGTTGTGCAGAAAACTGAAAC
AACTCGTTCTGGCCGTAACGCTGCTATCGTTAAGTTAAAGTTGAAAAACTTACTGCTTAACTCTGGTACTGAAACGACTT
TCAAAGGTGAAGATAAGTTAGAAGACATCATCCTAGATCGTCTTGATTGTACTTATTCTTACTTTGCTGATCCTATGTTT
GTATTCATGGATGCAGAATATAACCAATACGACGTAGAAGCTGAAAACTTAGGTGATGCAGCGGCTTATATCGTTGACGG
TATGGAAGAAACTTGCCAAGTGACTTTCTACGATGGCAAAGCTATCTCTGTTGAAATGCCAACCACTATCGTACGTGAAG
TGATCTACACTGAGCCTTCAGCTCGTGGCGATACTTCAGGTAAAGTGATGAAGCCTGCAACTATCACTGGCGGCGGCACT
GTTACTGTTGCTGACTTCGTGAAAGTTGGCGACAAGATTGAAATCGATACTCGTACTGGCGAATTCAAGAAGCGCGTTTA
A

Upstream 100 bases:

>100_bases
ATTAAATGCTGCAGATCTCGCTACTCGACTAGTTCAGTTCGTTAAAAACAGCTAAGATACTGCGCGAAAACAGAAAAATC
TAAATATAGGAAATAGTGTA

Downstream 100 bases:

>100_bases
TCGCCCTTCTCGTTTCCAGACGAAGAAAAGCCAGTGCTTGCACTGGCTTTTTTGTCGCAGTTTTTTTGTCGCGTGATTTG
TGGGATGTCGAGTCACTCAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKLEDIILDRLDCTYSYFADPMF
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
VTVADFVKVGDKIEIDTRTGEFKKRV

Sequences:

>Translated_186_residues
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKLEDIILDRLDCTYSYFADPMF
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
VTVADFVKVGDKIEIDTRTGEFKKRV
>Mature_186_residues
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKLEDIILDRLDCTYSYFADPMF
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
VTVADFVKVGDKIEIDTRTGEFKKRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=184, Percent_Identity=36.9565217391304, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=27.1276595744681, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_SHEB2 (B8E520)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358167.1
- ProteinModelPortal:   B8E520
- SMR:   B8E520
- GeneID:   7086372
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2245
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20584; Mature: 20584

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKL
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEEEHHHCCCCCCEECCCHHH
EDIILDRLDCTYSYFADPMFVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEHEECCCCCCEEEEEEECCE
AISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTVTVADFVKVGDKIEIDTRTG
EEEEECCHHHHHHHHHCCCCCCCCCCCCEECCEEECCCCEEEEEHHHHCCCEEEEECCCC
EFKKRV
CHHCCC
>Mature Secondary Structure
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKL
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEEEHHHCCCCCCEECCCHHH
EDIILDRLDCTYSYFADPMFVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEHEECCCCCCEEEEEEECCE
AISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTVTVADFVKVGDKIEIDTRTG
EEEEECCHHHHHHHHHCCCCCCCCCCCCEECCEEECCCCEEEEEHHHHCCCEEEEECCCC
EFKKRV
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA