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The map label for this gene is fldA [H]

Identifier: 126174446

GI number: 126174446

Start: 2577951

End: 2578478

Strand: Direct

Name: fldA [H]

Synonym: Sbal_2230

Alternate gene names: 126174446

Gene position: 2577951-2578478 (Clockwise)

Preceding gene: 126174445

Following gene: 126174447

Centisome position: 50.28

GC content: 45.08

Gene sequence:

>528_bases
ATGGCAACTGTAGGTCTTTTTTTCGGTAGCGACACAGGTAACACCGAAGCCGTAGCCAAGATGATCCAGAAAAAACTGGG
TAAAAAAATGGTTGAGGTGAAAGATATCGCCAAAAGTACCAAAGAACAGATTGCAGAGTATGACTTGCTGCTGTTCGGCA
TCCCGACCTGGTATTACGGCGAAGCTCAATGTGACTGGGATGATTTCTTCCCTGAACTAGAGCAAATTGATTTTACTGAC
AAACTTGTCGCTATTTTTGGTTGTGGTGATCAAGAAGACTACGCTGAGTATTTCCTTGATGCCATGGGCATGGTTGGCGA
TATCGTTCAGGCGCGTGGTGGTATCATCATTGGTCACTGGCCAACTGCAAGCTACAACTTCGAAGCCTCTAAAGGCCAAG
TTGATGACGACCACTTTATTGGTTTAGGTATCGATGAAGATCGCCAGCCAGAGCTGACCGAAGAGCGTGTCGATGCTTGG
GTTAAGCAAATTTACGAAGAAATGTGCTTAGCTGAATTAGAAGACTAA

Upstream 100 bases:

>100_bases
TAGCCAGTTAATCGAATTAATTCTTCAGCAACAAGTTGAGTGCTGAACGAGTACCAGCAAGATTAACGTAATAAGTGAAC
TAGACATTAAAGGATAGACA

Downstream 100 bases:

>100_bases
TTGGGCTAACCATTCGATTAAAGCGGCCTTAACGCCGCTTTTTTTATGCTTATATTTCTGACTAAGAATAACGACATACC
ACACTCATGACCAACACACC

Product: flavodoxin FldA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTD
KLVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHWPTASYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAW
VKQIYEEMCLAELED

Sequences:

>Translated_175_residues
MATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTD
KLVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHWPTASYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAW
VKQIYEEMCLAELED
>Mature_174_residues
ATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTDK
LVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHWPTASYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAWV
KQIYEEMCLAELED

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=173, Percent_Identity=72.2543352601156, Blast_Score=271, Evalue=1e-74,
Organism=Escherichia coli, GI1789262, Length=168, Percent_Identity=38.6904761904762, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 19792; Mature: 19661

Theoretical pI: Translated: 3.89; Mature: 3.89

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEECC
EAQCDWDDFFPELEQIDFTDKLVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHW
CCCCCHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
PTASYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAWVKQIYEEMCLAELED
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYG
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEECC
EAQCDWDDFFPELEQIDFTDKLVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHW
CCCCCHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
PTASYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAWVKQIYEEMCLAELED
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]