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The map label for this gene is cheB2 [H]

Identifier: 126174336

GI number: 126174336

Start: 2457170

End: 2458219

Strand: Direct

Name: cheB2 [H]

Synonym: Sbal_2117

Alternate gene names: 126174336

Gene position: 2457170-2458219 (Clockwise)

Preceding gene: 126174335

Following gene: 126174338

Centisome position: 47.92

GC content: 50.0

Gene sequence:

>1050_bases
ATGACGATCAAAGTGCTAGTAGTTGACGATTCCGCGCTGATGCGCAGCTTGCTCGGTAAAATGATTGAGGCTGACCCTGA
ACTGTCTCTGGTTGGGCAAGCTGCCGATGCCTTTGAGGCCAAGGATCTAGTGAATCAATTTCGCCCCGATGTGATCACCT
TAGACATCGAAATGCCTAAAGTGGATGGCTTAACCTTTCTGGACCGCTTGATGAAAGCCAGACCCACAGCGGTAGTGATG
ATTTCTTCGTTAACCGAGCAGGGCGCAGATGCGACCTTTAACGCCTTAGCCTTAGGCGCGGTAGATTTTATCCCGAAACC
GAAATTAGACTCGCCCCAAGGTATCCATGATTATCAGGATTTGATTTTAGATAAGATCAAATCCGCCGCGAAAGCCAAAA
TCATCAAACCGCAAAAATTTGTTGAGCCAACACGCCCAGTGTCGAGTAAGCGGCCGGTATTGGCCAATACAACCCTAACC
CAGCATCTAGTTGCGATAGGCGCCTCTACAGGCGGCACCGAAGCCATTTTGTATGTGTTACAGCATTTACCTGCGGCTAT
GCCACCGATAGTGATCACCCAACATATGCCAGCGGGGTTTACCCGCACTTTTGCCGAACGCTTAAATCGACTGTCGCGGA
TCACAGTCAAAGAAGCCGAGCACGGTGAGCGACTTTTACCCAGTTATGCCTATGTTGCCCCTGGCGATCATCACCTTGAG
ATCATCAAAGTGGGTGGCAGTTATAAAGTGAAATTAACCCAAGATGAAAAGGTCAGCGGCCACAGGCCATCGGTCGATGT
GATGTTTAATGCCTTGGCCCAATGCGCCGCGCCCAATATCAGCGCGATGATATTAACCGGCATGGGTAAAGATGGCGCCG
AAGGTATGGTGGCGCTGCATCAAAAAGGCGTCACCACCTTTGCCCAAGATGAACAAAGTTGTGTGGTATTTGGTATGCCA
AGGGAAGCGATAAAGTGCCGCGCGGTGGATTATGTGGTGGAGTTGTCGCAGATGCCGAGTAAACTTATCAACCACTTAAG
CTCACTGTGA

Upstream 100 bases:

>100_bases
TTTGCACAACAGCACGATCCTTGACCGAGAAAGCGAGTATCGCTTACGGGTTCGTAATCTCCCCACGGGCGGCGACGTTG
AACTATTTGGTGATTAAGTT

Downstream 100 bases:

>100_bases
TTGCTGCCTTTAACGTGCTTAAAAAGTAATCATCAATATGGCGGTGAGTCAAACCGAATGACATTACGGCCTGATTCATG
CGTCGGATGAGTGAATGGGT

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTIKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPKVDGLTFLDRLMKARPTAVVM
ISSLTEQGADATFNALALGAVDFIPKPKLDSPQGIHDYQDLILDKIKSAAKAKIIKPQKFVEPTRPVSSKRPVLANTTLT
QHLVAIGASTGGTEAILYVLQHLPAAMPPIVITQHMPAGFTRTFAERLNRLSRITVKEAEHGERLLPSYAYVAPGDHHLE
IIKVGGSYKVKLTQDEKVSGHRPSVDVMFNALAQCAAPNISAMILTGMGKDGAEGMVALHQKGVTTFAQDEQSCVVFGMP
REAIKCRAVDYVVELSQMPSKLINHLSSL

Sequences:

>Translated_349_residues
MTIKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPKVDGLTFLDRLMKARPTAVVM
ISSLTEQGADATFNALALGAVDFIPKPKLDSPQGIHDYQDLILDKIKSAAKAKIIKPQKFVEPTRPVSSKRPVLANTTLT
QHLVAIGASTGGTEAILYVLQHLPAAMPPIVITQHMPAGFTRTFAERLNRLSRITVKEAEHGERLLPSYAYVAPGDHHLE
IIKVGGSYKVKLTQDEKVSGHRPSVDVMFNALAQCAAPNISAMILTGMGKDGAEGMVALHQKGVTTFAQDEQSCVVFGMP
REAIKCRAVDYVVELSQMPSKLINHLSSL
>Mature_348_residues
TIKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPKVDGLTFLDRLMKARPTAVVMI
SSLTEQGADATFNALALGAVDFIPKPKLDSPQGIHDYQDLILDKIKSAAKAKIIKPQKFVEPTRPVSSKRPVLANTTLTQ
HLVAIGASTGGTEAILYVLQHLPAAMPPIVITQHMPAGFTRTFAERLNRLSRITVKEAEHGERLLPSYAYVAPGDHHLEI
IKVGGSYKVKLTQDEKVSGHRPSVDVMFNALAQCAAPNISAMILTGMGKDGAEGMVALHQKGVTTFAQDEQSCVVFGMPR
EAIKCRAVDYVVELSQMPSKLINHLSSL

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=346, Percent_Identity=50.2890173410405, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI87082052, Length=105, Percent_Identity=32.3809523809524, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37857; Mature: 37725

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPK
CEEEEEEECCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
VDGLTFLDRLMKARPTAVVMISSLTEQGADATFNALALGAVDFIPKPKLDSPQGIHDYQD
CCCHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LILDKIKSAAKAKIIKPQKFVEPTRPVSSKRPVLANTTLTQHLVAIGASTGGTEAILYVL
HHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHH
QHLPAAMPPIVITQHMPAGFTRTFAERLNRLSRITVKEAEHGERLLPSYAYVAPGDHHLE
HHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCCCEE
IIKVGGSYKVKLTQDEKVSGHRPSVDVMFNALAQCAAPNISAMILTGMGKDGAEGMVALH
EEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHH
QKGVTTFAQDEQSCVVFGMPREAIKCRAVDYVVELSQMPSKLINHLSSL
HCCCCEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPK
EEEEEEECCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
VDGLTFLDRLMKARPTAVVMISSLTEQGADATFNALALGAVDFIPKPKLDSPQGIHDYQD
CCCHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LILDKIKSAAKAKIIKPQKFVEPTRPVSSKRPVLANTTLTQHLVAIGASTGGTEAILYVL
HHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHH
QHLPAAMPPIVITQHMPAGFTRTFAERLNRLSRITVKEAEHGERLLPSYAYVAPGDHHLE
HHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCCCEE
IIKVGGSYKVKLTQDEKVSGHRPSVDVMFNALAQCAAPNISAMILTGMGKDGAEGMVALH
EEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHH
QKGVTTFAQDEQSCVVFGMPREAIKCRAVDYVVELSQMPSKLINHLSSL
HCCCCEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA