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The map label for this gene is tcp [H]

Identifier: 126174333

GI number: 126174333

Start: 2453740

End: 2455713

Strand: Direct

Name: tcp [H]

Synonym: Sbal_2114

Alternate gene names: 126174333

Gene position: 2453740-2455713 (Clockwise)

Preceding gene: 126174332

Following gene: 126174334

Centisome position: 47.86

GC content: 48.43

Gene sequence:

>1974_bases
ATGAGTATCTTCAAATTTTTTGGCAATGATGAAGCGCGTGAGCAAAGGGATGAAGAGCGTCAGCGCTATTTTCAGCTACT
CGATAACAGTGGCAACAGCTTCATGATTGCTGACAGTCAGCGCAATATCATCTATGCGAATAAAGCCGTCGTCCGCTTGC
TGCAAGAGGCCGAGGATGATATTCGTAAAGAGTTACCCCAATTCTCGGTCGCTAAACTGATCGGCAGTAATATCGATATT
TTCCATAAAAATCCAGCGCATCAACGCAACCTGTTAGAGCGTTTGACTCAGTCCCATACTGCGCAAATCACCATTGGCAA
GCGTACCTTTAGGTTGATTCTGACGCCGATTATCACCTCTGAAAATAAACACTTAGGTACAGGTGTTGAGTGGATAGATC
GCACCGAAAGTATCGAAGCCGAGCGCGCAACCCAGCGTATTATGGAAGCGCTCAACAATACCAGTACCAACGTCATGATC
GCCGATGCTAACCGTACCATCATTTATATGAATCGCTCGGTCGAAGCCATGTTACGTCAGTCTGAGCATGAAATTAGGCA
GGCTTTACCGCATTTTTCCGTGGATAAAATCCTCGGCAGCTCGATGGATATTTTCCATCGCAATCCTGCCCACCAAGCGA
GTTTACTCGATAAATTAGACCGCAAATATGAATCGCTGATTAAGGTGGCCAGCTGCCATTTCCGTTTAACCGCCAGCCCC
ATAGTGTCAAAAGAAGGCGAGCGCTTAGGGACAGTGGTTGAATGGCTCGACCGCACCATTGAAGTGCAAACTGAGCAGGA
GATTTCCCGCATTGTGACCGCAGCAGCAGCGGGAGATTTCTCCCAAAGGGCGGACACCGAAGGCAAGCAAGGTTTCTTCC
TGATGTTGGCGAACAACTTGAATTCGTTAATTGAAACCTCAGACCGTGGACTACAAGATGTGGCGCGCGTACTGATGGCG
CTGGCGGATGGCGATCTCACCACCCGCATTTATAACGACTATGAAGGCACGTTTAATGATTTGAAAAACTACTCAAATCA
AACCGCTGAAAAGCTATCTTTCATGATCCAAGATATTCAGCGAGCGGCGGATACCATTAATACCGCCTCAGCAGAAATTG
CCCAAGGCAACGCCGATTTATCCAGCCGCACCGAAGAACAAGCTTCGAGCCTAGAAGAAACCTCCGCCAGCATGGAGGAA
CTCACAGGTACAGTGAAACTCAATGCGGATAACGCCAGCCAAGCCAATGCCTTAGCCTCTAAAGCATCGGAAGTGGCAGT
GGACGGTGGTGAGCTTATCCAGCAAGTCGTACAGACCATGGCATCGATTAATGAATCGGCGCGTAAGATTGCCGACATTA
TTGGTGTTATCGATGGTATTGCTTTCCAAACCAATATCTTAGCGCTTAATGCCGCCGTTGAAGCCGCGCGGGCGGGTGAG
CAAGGACGCGGCTTTGCAGTAGTCGCATCAGAAGTACGCAGCTTAGCCCAACGCTCGACCAATGCCGCTAAAGATATCAA
GGCATTGATCTCGGATTCTGTCACTAAGATCGAAAGCGGCAACAGTCTCGTCGGTAAGTCGGGCGATACCATGAAAGAAA
TCGTCATTGCCATTAAACGGGTGAACGACATCATGGCGGAGATTGCCTCAGCGTCCAATGAACAAGCACTTGGTATAGAT
GAGATCAGCAAAGCTGTGGTGCAAATGGATGAAATGACCCAGCAAAATGCTGCCTTGGTTGAAGAAGCGGCCGCTGCAGC
TGAAAGCATGCAATCTCAAGCGCAACAATTATCAGACAGTGTTGCCAGCTTCCGCGTAGATGACGATGAACAGCCGCATG
TTGTTCAGCCCACAAAGAAGAAAAAGCTTACGGCAAACACCACCTCGCTGACGGTTGCTCGTATGCCCGTTAAAGCAAAA
ATGCCCATGCCAAAATTGAAAAAAGTGGATCAAGATGAATGGGAAGAATTTTAA

Upstream 100 bases:

>100_bases
AGGATAAGATGATCATTTTAGTAAATATTCAGGCTCTGATCAGCAGTGATGAGCTGGGTCTAATTGATGCAAATAGTCTG
ACTGATCAGGAGTAACAATA

Downstream 100 bases:

>100_bases
TTGAGCGAGCTTAAATCGTTGGAGCGGGAGTTTGCCTATACCACGGCGCATTTTAATACTGCGCGGACGACGCTATATCG
GTTTTCAGGTATTAAACTTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MSIFKFFGNDEAREQRDEERQRYFQLLDNSGNSFMIADSQRNIIYANKAVVRLLQEAEDDIRKELPQFSVAKLIGSNIDI
FHKNPAHQRNLLERLTQSHTAQITIGKRTFRLILTPIITSENKHLGTGVEWIDRTESIEAERATQRIMEALNNTSTNVMI
ADANRTIIYMNRSVEAMLRQSEHEIRQALPHFSVDKILGSSMDIFHRNPAHQASLLDKLDRKYESLIKVASCHFRLTASP
IVSKEGERLGTVVEWLDRTIEVQTEQEISRIVTAAAAGDFSQRADTEGKQGFFLMLANNLNSLIETSDRGLQDVARVLMA
LADGDLTTRIYNDYEGTFNDLKNYSNQTAEKLSFMIQDIQRAADTINTASAEIAQGNADLSSRTEEQASSLEETSASMEE
LTGTVKLNADNASQANALASKASEVAVDGGELIQQVVQTMASINESARKIADIIGVIDGIAFQTNILALNAAVEAARAGE
QGRGFAVVASEVRSLAQRSTNAAKDIKALISDSVTKIESGNSLVGKSGDTMKEIVIAIKRVNDIMAEIASASNEQALGID
EISKAVVQMDEMTQQNAALVEEAAAAAESMQSQAQQLSDSVASFRVDDDEQPHVVQPTKKKKLTANTTSLTVARMPVKAK
MPMPKLKKVDQDEWEEF

Sequences:

>Translated_657_residues
MSIFKFFGNDEAREQRDEERQRYFQLLDNSGNSFMIADSQRNIIYANKAVVRLLQEAEDDIRKELPQFSVAKLIGSNIDI
FHKNPAHQRNLLERLTQSHTAQITIGKRTFRLILTPIITSENKHLGTGVEWIDRTESIEAERATQRIMEALNNTSTNVMI
ADANRTIIYMNRSVEAMLRQSEHEIRQALPHFSVDKILGSSMDIFHRNPAHQASLLDKLDRKYESLIKVASCHFRLTASP
IVSKEGERLGTVVEWLDRTIEVQTEQEISRIVTAAAAGDFSQRADTEGKQGFFLMLANNLNSLIETSDRGLQDVARVLMA
LADGDLTTRIYNDYEGTFNDLKNYSNQTAEKLSFMIQDIQRAADTINTASAEIAQGNADLSSRTEEQASSLEETSASMEE
LTGTVKLNADNASQANALASKASEVAVDGGELIQQVVQTMASINESARKIADIIGVIDGIAFQTNILALNAAVEAARAGE
QGRGFAVVASEVRSLAQRSTNAAKDIKALISDSVTKIESGNSLVGKSGDTMKEIVIAIKRVNDIMAEIASASNEQALGID
EISKAVVQMDEMTQQNAALVEEAAAAAESMQSQAQQLSDSVASFRVDDDEQPHVVQPTKKKKLTANTTSLTVARMPVKAK
MPMPKLKKVDQDEWEEF
>Mature_656_residues
SIFKFFGNDEAREQRDEERQRYFQLLDNSGNSFMIADSQRNIIYANKAVVRLLQEAEDDIRKELPQFSVAKLIGSNIDIF
HKNPAHQRNLLERLTQSHTAQITIGKRTFRLILTPIITSENKHLGTGVEWIDRTESIEAERATQRIMEALNNTSTNVMIA
DANRTIIYMNRSVEAMLRQSEHEIRQALPHFSVDKILGSSMDIFHRNPAHQASLLDKLDRKYESLIKVASCHFRLTASPI
VSKEGERLGTVVEWLDRTIEVQTEQEISRIVTAAAAGDFSQRADTEGKQGFFLMLANNLNSLIETSDRGLQDVARVLMAL
ADGDLTTRIYNDYEGTFNDLKNYSNQTAEKLSFMIQDIQRAADTINTASAEIAQGNADLSSRTEEQASSLEETSASMEEL
TGTVKLNADNASQANALASKASEVAVDGGELIQQVVQTMASINESARKIADIIGVIDGIAFQTNILALNAAVEAARAGEQ
GRGFAVVASEVRSLAQRSTNAAKDIKALISDSVTKIESGNSLVGKSGDTMKEIVIAIKRVNDIMAEIASASNEQALGIDE
ISKAVVQMDEMTQQNAALVEEAAAAAESMQSQAQQLSDSVASFRVDDDEQPHVVQPTKKKKLTANTTSLTVARMPVKAKM
PMPKLKKVDQDEWEEF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=339, Percent_Identity=51.3274336283186, Blast_Score=292, Evalue=5e-80,
Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=55.8441558441558, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1787690, Length=301, Percent_Identity=53.156146179402, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=52.8813559322034, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=43.5483870967742, Blast_Score=199, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 72445; Mature: 72314

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFKFFGNDEAREQRDEERQRYFQLLDNSGNSFMIADSQRNIIYANKAVVRLLQEAEDD
CCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHH
IRKELPQFSVAKLIGSNIDIFHKNPAHQRNLLERLTQSHTAQITIGKRTFRLILTPIITS
HHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHCC
ENKHLGTGVEWIDRTESIEAERATQRIMEALNNTSTNVMIADANRTIIYMNRSVEAMLRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHH
SEHEIRQALPHFSVDKILGSSMDIFHRNPAHQASLLDKLDRKYESLIKVASCHFRLTASP
HHHHHHHHCCCCCHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
IVSKEGERLGTVVEWLDRTIEVQTEQEISRIVTAAAAGDFSQRADTEGKQGFFLMLANNL
HHCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEHHHH
NSLIETSDRGLQDVARVLMALADGDLTTRIYNDYEGTFNDLKNYSNQTAEKLSFMIQDIQ
HHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RAADTINTASAEIAQGNADLSSRTEEQASSLEETSASMEELTGTVKLNADNASQANALAS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
KASEVAVDGGELIQQVVQTMASINESARKIADIIGVIDGIAFQTNILALNAAVEAARAGE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVASEVRSLAQRSTNAAKDIKALISDSVTKIESGNSLVGKSGDTMKEIVIAIKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VNDIMAEIASASNEQALGIDEISKAVVQMDEMTQQNAALVEEAAAAAESMQSQAQQLSDS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASFRVDDDEQPHVVQPTKKKKLTANTTSLTVARMPVKAKMPMPKLKKVDQDEWEEF
HHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCHHHHCCCCHHHCCC
>Mature Secondary Structure 
SIFKFFGNDEAREQRDEERQRYFQLLDNSGNSFMIADSQRNIIYANKAVVRLLQEAEDD
CCEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHH
IRKELPQFSVAKLIGSNIDIFHKNPAHQRNLLERLTQSHTAQITIGKRTFRLILTPIITS
HHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHCC
ENKHLGTGVEWIDRTESIEAERATQRIMEALNNTSTNVMIADANRTIIYMNRSVEAMLRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHH
SEHEIRQALPHFSVDKILGSSMDIFHRNPAHQASLLDKLDRKYESLIKVASCHFRLTASP
HHHHHHHHCCCCCHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
IVSKEGERLGTVVEWLDRTIEVQTEQEISRIVTAAAAGDFSQRADTEGKQGFFLMLANNL
HHCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEHHHH
NSLIETSDRGLQDVARVLMALADGDLTTRIYNDYEGTFNDLKNYSNQTAEKLSFMIQDIQ
HHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RAADTINTASAEIAQGNADLSSRTEEQASSLEETSASMEELTGTVKLNADNASQANALAS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
KASEVAVDGGELIQQVVQTMASINESARKIADIIGVIDGIAFQTNILALNAAVEAARAGE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVASEVRSLAQRSTNAAKDIKALISDSVTKIESGNSLVGKSGDTMKEIVIAIKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VNDIMAEIASASNEQALGIDEISKAVVQMDEMTQQNAALVEEAAAAAESMQSQAQQLSDS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASFRVDDDEQPHVVQPTKKKKLTANTTSLTVARMPVKAKMPMPKLKKVDQDEWEEF
HHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]