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The map label for this gene is zitB [C]

Identifier: 126174320

GI number: 126174320

Start: 2436521

End: 2437630

Strand: Direct

Name: zitB [C]

Synonym: Sbal_2100

Alternate gene names: 126174320

Gene position: 2436521-2437630 (Clockwise)

Preceding gene: 126174318

Following gene: 126174321

Centisome position: 47.52

GC content: 47.84

Gene sequence:

>1110_bases
ATGAGTTTTCGAATCAGAACCGCGATGGCGAAAAAAACACACGCTATGTACTGTATTTACGGTTCTATGGCATTGCTCGC
CGACGGTTGGCACATGGGCACCCATGCTGCGGCCTTTATGATCACCTTGTTTGCCTATTCCTATGCCCGTAAACACGCTA
ACGATCCCGCCTTCGCCTTTGGTACAGGTAAGGTGAGTGTGCTTGGCGGTTACACTAGTGCAATAGCCTTAGGTTTAGTG
GCATTGGTGATGTTGATTGAATCGGGAATGCGGCTGATCAGTCCTGAGCAAATTCATTTCAACGAAGCTATTTTTGTGGC
CGTTATTGGTTTAAGCGTCAATATACTGAGTGTGTTTTTACTTAAAGATCATCATACCCACGATCACGGGCATCACCACG
GTCATGGACATGATCATAGTCACGACCATGAACATGATCATGATCATGCGCATCATAACAGCCAAGCACACACCCATGAC
GATCATGCCCATACAGCGCATTCAGATGATGTGGATCCGCACCCGCACCATGACTCACATGCACACGATGAAAGTCATCA
TGATCATAGCCATTGCCAACATGAACAGGATCACCAACATGCTGCAGAGCATGAGCATGAGCATGAGCATGAGCACAAGA
GCCAAAAGGACCACGGTGGCCATGATCACAACCTACGTGCGGCCTATTTTCACGTACTAGCCGATGCATTAACTTCAGTG
CTGGCCATCGCTGCCTTGTTGTTTGGTAAATACATGGGACTAACTTGGCTCGACCCGATTATGGGGATTGTCGGCGCTGT
GATTATCAGCCGTTGGTCTTGGGGACTCATTCAGCAAACGAGCCCTATTTTGCTGGACGGCGGCGTTAAAGCGTCATTGC
AACGTAAAGTCACACAAACCATTGAAGCTGTAACGGATCATCAAGTGGCCGATTTACATCTTTGGCGAGTGAGCGCCGAT
CACCATGCTATTATGGTGTCCATCGTGTCCCATTCACCGAAAGATGTCAGTTATTTTAATCAGTTACTGTCACAATTTCC
TGAATTGGCCCATATCACCATTGAACTCCATACTTGCCGTCAGCGCGAGTGTATGGCTAAGGAAGCCTAA

Upstream 100 bases:

>100_bases
AGGAATTACACAATGAAATCAACAGCAGCCGAGCAAGCGACAGGGCATCAAGCTTCAGCCCACCGCCAAGGGCACTCACT
CGCCCAGTGGCAACACTCAC

Downstream 100 bases:

>100_bases
TGACTGTTGAACATCATCATTCATCAAACCTGCATTCAAGTGAGCCACATTCGACTGCTCACTCAACAGCTGGACATTCA
ACGGCCGCACATTCAACCGA

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: Cation Efflux Protein; Cation Efflux System Protein; Cation Efflux Family Protein; Co/Zn/Cd Efflux System Component; Metal Transporter; Cation Transporter; Histidine-Rich Transporter Transmembrane Protein; Heavy Metal Transporter; Co/Zn/Cd Efflux System Component Protein; Cation Efflux Transporter; Metal Transport Transmembrane Protein; CDF Family Heavy Metal/H(+) Antiporter; CDF-Family Cation Efflux System Protein; Cobalt-Zinc-Cadmium Resistance Protein CzcD; Transmembrane Transporter; Zinc Transporter ZitB

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSFRIRTAMAKKTHAMYCIYGSMALLADGWHMGTHAAAFMITLFAYSYARKHANDPAFAFGTGKVSVLGGYTSAIALGLV
ALVMLIESGMRLISPEQIHFNEAIFVAVIGLSVNILSVFLLKDHHTHDHGHHHGHGHDHSHDHEHDHDHAHHNSQAHTHD
DHAHTAHSDDVDPHPHHDSHAHDESHHDHSHCQHEQDHQHAAEHEHEHEHEHKSQKDHGGHDHNLRAAYFHVLADALTSV
LAIAALLFGKYMGLTWLDPIMGIVGAVIISRWSWGLIQQTSPILLDGGVKASLQRKVTQTIEAVTDHQVADLHLWRVSAD
HHAIMVSIVSHSPKDVSYFNQLLSQFPELAHITIELHTCRQRECMAKEA

Sequences:

>Translated_369_residues
MSFRIRTAMAKKTHAMYCIYGSMALLADGWHMGTHAAAFMITLFAYSYARKHANDPAFAFGTGKVSVLGGYTSAIALGLV
ALVMLIESGMRLISPEQIHFNEAIFVAVIGLSVNILSVFLLKDHHTHDHGHHHGHGHDHSHDHEHDHDHAHHNSQAHTHD
DHAHTAHSDDVDPHPHHDSHAHDESHHDHSHCQHEQDHQHAAEHEHEHEHEHKSQKDHGGHDHNLRAAYFHVLADALTSV
LAIAALLFGKYMGLTWLDPIMGIVGAVIISRWSWGLIQQTSPILLDGGVKASLQRKVTQTIEAVTDHQVADLHLWRVSAD
HHAIMVSIVSHSPKDVSYFNQLLSQFPELAHITIELHTCRQRECMAKEA
>Mature_368_residues
SFRIRTAMAKKTHAMYCIYGSMALLADGWHMGTHAAAFMITLFAYSYARKHANDPAFAFGTGKVSVLGGYTSAIALGLVA
LVMLIESGMRLISPEQIHFNEAIFVAVIGLSVNILSVFLLKDHHTHDHGHHHGHGHDHSHDHEHDHDHAHHNSQAHTHDD
HAHTAHSDDVDPHPHHDSHAHDESHHDHSHCQHEQDHQHAAEHEHEHEHEHKSQKDHGGHDHNLRAAYFHVLADALTSVL
AIAALLFGKYMGLTWLDPIMGIVGAVIISRWSWGLIQQTSPILLDGGVKASLQRKVTQTIEAVTDHQVADLHLWRVSADH
HAIMVSIVSHSPKDVSYFNQLLSQFPELAHITIELHTCRQRECMAKEA

Specific function: Involved In Zinc Efflux Across The Cytoplasmic Membrane, Thus Reducing Zinc Accumulation In The Cytoplasm And Rendering Bacteria More Resistant To Zinc. It May Contribute To Zinc Homeostasis At Low Concentrations Of Zinc, Whereas Znta Is Required For Grow

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI222080086, Length=339, Percent_Identity=25.9587020648968, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI40255009, Length=339, Percent_Identity=25.9587020648968, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32564488, Length=104, Percent_Identity=36.5384615384615, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323899, Length=309, Percent_Identity=25.8899676375405, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324892, Length=283, Percent_Identity=23.321554770318, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585900, Length=326, Percent_Identity=20.8588957055215, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24585898, Length=326, Percent_Identity=20.8588957055215, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24585896, Length=326, Percent_Identity=20.8588957055215, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI19921672, Length=326, Percent_Identity=20.8588957055215, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41283; Mature: 41152

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRIRTAMAKKTHAMYCIYGSMALLADGWHMGTHAAAFMITLFAYSYARKHANDPAFAF
CCEEHHHHHHHHHCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GTGKVSVLGGYTSAIALGLVALVMLIESGMRLISPEQIHFNEAIFVAVIGLSVNILSVFL
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCEEEEHHHHHHHHHHHHHH
LKDHHTHDHGHHHGHGHDHSHDHEHDHDHAHHNSQAHTHDDHAHTAHSDDVDPHPHHDSH
HHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHDESHHDHSHCQHEQDHQHAAEHEHEHEHEHKSQKDHGGHDHNLRAAYFHVLADALTSV
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LAIAALLFGKYMGLTWLDPIMGIVGAVIISRWSWGLIQQTSPILLDGGVKASLQRKVTQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHHHHHH
IEAVTDHQVADLHLWRVSADHHAIMVSIVSHSPKDVSYFNQLLSQFPELAHITIELHTCR
HHHHHCCCHHEEEEEEECCCCCEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEEECHH
QRECMAKEA
HHHHHHCCC
>Mature Secondary Structure 
SFRIRTAMAKKTHAMYCIYGSMALLADGWHMGTHAAAFMITLFAYSYARKHANDPAFAF
CEEHHHHHHHHHCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GTGKVSVLGGYTSAIALGLVALVMLIESGMRLISPEQIHFNEAIFVAVIGLSVNILSVFL
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCEEEEHHHHHHHHHHHHHH
LKDHHTHDHGHHHGHGHDHSHDHEHDHDHAHHNSQAHTHDDHAHTAHSDDVDPHPHHDSH
HHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHDESHHDHSHCQHEQDHQHAAEHEHEHEHEHKSQKDHGGHDHNLRAAYFHVLADALTSV
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LAIAALLFGKYMGLTWLDPIMGIVGAVIISRWSWGLIQQTSPILLDGGVKASLQRKVTQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHHHHHH
IEAVTDHQVADLHLWRVSADHHAIMVSIVSHSPKDVSYFNQLLSQFPELAHITIELHTCR
HHHHHCCCHHEEEEEEECCCCCEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEEECHH
QRECMAKEA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA