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The map label for this gene is fadH [H]

Identifier: 126174277

GI number: 126174277

Start: 2382562

End: 2384580

Strand: Direct

Name: fadH [H]

Synonym: Sbal_2056

Alternate gene names: 126174277

Gene position: 2382562-2384580 (Clockwise)

Preceding gene: 126174274

Following gene: 126174283

Centisome position: 46.47

GC content: 50.87

Gene sequence:

>2019_bases
ATGTCGTTTCCCCATTTATTAGAACCCTTAGATCTGGGATTTACCCAGCTCAAAAACCGCGTGCTTATGGGCTCAATGCA
CACAGGTTTGGAAGAAGAAAAGGGCGGATTTGAGAAACTGGCAGCGTTCTACAAAGAACGCGCTCTGGGCGGTGTGGGTT
TGATTGTGACGGGTGGTATTTCCCCTAATCTTCGTGGCCGCCTTACGCCCCATGCCTGTCAGCTGAGTTTTCCTTGGCAA
GTCGGTAAGCATCGCGTGGTCACGCAGGCGGTGCATGAGGCTGGCGGTAAGATCTGTATGCAAATTTTGCATGCGGGCCG
CTACGGTTATCATCCTTTTTCCCAAGCACCGAGCAAGATTAAATCACCGATTACACCTTTTACGCCGTCTGCTATGTCTA
GTCGCCAAGTGCGCTCGACCATTAAGGATTACGCCAGCTCCGCCGCCCTTGCCAAGAAAGCCGGTTACGATGGCGTCGAG
GTCATGGGCTCAGAAGGCTATTTGATCAATCAGTTTGTCAGTGCGCGCACCAACACCCGCACCGATGAATGGGGCGGCGC
GTTTGAAAAGCGCGCGCAATTCCCAATTGAGATTGTTAACGCGATACGGGCAAAGGTCGGAAAAGACTTCATCATTATCT
TCCGTTTATCTATGCTCGATCTAGTGGATAACGGCTCGACTTGGGATGAAGTGGTGCAGCTCGCCCAGTGGTTAGAGCAA
GCTGGCGTGTCCATTTTGAATACCGGCATTGGTTGGCATGAAGCGCGTGTACCGACAATTGCGACAAGTGTGCCCCGCGG
CGCCTTTGCGTGGGTGACTGAAAAGCTCAAACAATCAGTTTCTGTGCCCTTAATTGCGACTAACCGCATTAACACCCCTG
AGATTGGCGAGCAGATCATTGCCTCTGGTCAAGCTGACATGGTGTCGATGGCAAGGCCTTTCCTTGCCGATCCTGAGTTT
GTGAATAAAGCCGCGGCGAACACGCCAGAGCTTATCAACACTTGCATTGGCTGTAACCAAGCGTGCCTTGACCATACTTT
TGCACTTAAGCGTGCGACCTGCTTAGTGAATCCTCGTGCCTGTTATGAGACTGAAATCAACTTCTTACCCACAGCAAATA
AAAAGCGTATTGCGGTGATGGGCGCAGGTCCTGCGGGCATGGCGTTCTCTGTCTATGCCGCCATGCGTGGCCATCACGTT
GTCTTGTTTGAAGCGAAATCCGAGGTGGGTGGCCAGTTTAATCTCGCCCGTAAAATCCCTGGGAAAGAAGAGTTTAACGA
GACTATCCGTTATTTCATCAATCAAATTAATTTGCATAAGGTGGAGCTGAGATTAAACACTCGCCTTGATGCCAGCGTGT
TGGCAACCGAAAAGTTTGATGAAGTGGTGATAGCGTCAGGCGTTGTGCCGCGTGATTTAGTCTTACCCGGCTTTGATGAC
CCACGCGTGGTCGATTATCAAAAAGTGCTCTCGGGTGAAGTGACCGTCGGTAATACGGTGGCCTTGATTGGTGCTGGCGG
CATAGGGTTCGATATGGCGCACTTTTTGTGTGAGCGCCAATCTAGCACATTGAACGCTGATAAATGGCTGCAACAGTGGG
GCATAGATAAAACTTACCAACATGCGGGCGGCCTAACAGAACCTCATTCCGATAATACCGATCATCGTAAGGTGTTTTTA
CTGCAACGTAAAACGTCGAAGATGGGTAAAGGCTTAGGTAAAACCACCGGCTGGATCCACCGTCTTGTGCTTAAGCAACA
TGATGTGAAGATGAAAACGGGCGTGAGTTACGATAAGTTTGATTATGCGGGACTGCATATTCGCGTGGGCGAAACCGCTG
AAGTGCTGGCCGTTGATAATGTTGTGCTTTGCGCTGGACAAGAATCGAATCGCACCTTAGTGGATGAGATGAAAGCGACG
GGCTTGCCTGTGCATCTGATTGGCGGCGTGGATGTCGCGGCAGAGCTTGATGCTAAGCGTGCAATTCGCCAAGGCGCTGA
GCTGGCAATGCGTTTATAG

Upstream 100 bases:

>100_bases
ATTGTAAAGGATTTTGACTGATGGCCTCGATCCAACGGTTGAGCTTAGATTTGACTCAAGGTATGCTGATTTAAATCACT
TGTTTTAAAAGGATGTTTGA

Downstream 100 bases:

>100_bases
AAACTCGATAAGTCTTCTGCGATAAGCTTTAGGCGTTAAGTTTTAGAGCCTGAAAGCCTGAACCTGTGTTCAGGCTTTTT
TGTTTTGGTTTTCCGCGGGA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVE
VMGSEGYLINQFVSARTNTRTDEWGGAFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
AGVSILNTGIGWHEARVPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHHV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFINQINLHKVELRLNTRLDASVLATEKFDEVVIASGVVPRDLVLPGFDD
PRVVDYQKVLSGEVTVGNTVALIGAGGIGFDMAHFLCERQSSTLNADKWLQQWGIDKTYQHAGGLTEPHSDNTDHRKVFL
LQRKTSKMGKGLGKTTGWIHRLVLKQHDVKMKTGVSYDKFDYAGLHIRVGETAEVLAVDNVVLCAGQESNRTLVDEMKAT
GLPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Sequences:

>Translated_672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVE
VMGSEGYLINQFVSARTNTRTDEWGGAFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
AGVSILNTGIGWHEARVPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHHV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFINQINLHKVELRLNTRLDASVLATEKFDEVVIASGVVPRDLVLPGFDD
PRVVDYQKVLSGEVTVGNTVALIGAGGIGFDMAHFLCERQSSTLNADKWLQQWGIDKTYQHAGGLTEPHSDNTDHRKVFL
LQRKTSKMGKGLGKTTGWIHRLVLKQHDVKMKTGVSYDKFDYAGLHIRVGETAEVLAVDNVVLCAGQESNRTLVDEMKAT
GLPVHLIGGVDVAAELDAKRAIRQGAELAMRL
>Mature_671_residues
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQV
GKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEV
MGSEGYLINQFVSARTNTRTDEWGGAFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQA
GVSILNTGIGWHEARVPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEFV
NKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHHVV
LFEAKSEVGGQFNLARKIPGKEEFNETIRYFINQINLHKVELRLNTRLDASVLATEKFDEVVIASGVVPRDLVLPGFDDP
RVVDYQKVLSGEVTVGNTVALIGAGGIGFDMAHFLCERQSSTLNADKWLQQWGIDKTYQHAGGLTEPHSDNTDHRKVFLL
QRKTSKMGKGLGKTTGWIHRLVLKQHDVKMKTGVSYDKFDYAGLHIRVGETAEVLAVDNVVLCAGQESNRTLVDEMKATG
LPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=678, Percent_Identity=56.3421828908555, Blast_Score=781, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=27.5071633237822, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=248, Percent_Identity=26.6129032258064, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=26.4, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=175, Percent_Identity=30.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=235, Percent_Identity=26.3829787234043, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=248, Percent_Identity=24.5967741935484, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=250, Percent_Identity=26, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=345, Percent_Identity=23.768115942029, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=29.0598290598291, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=353, Percent_Identity=22.9461756373938, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73514; Mature: 73383

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEVMGSEGYLINQFVSARTNTR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDEWGGAFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
CCHHCCHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVSILNTGIGWHEARVPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHHVVLFEAKSEVGGQFNLARKIP
HHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFINQINLHKVELRLNTRLDASVLATEKFDEVVIASGVVPRDLVLPGFDD
CHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCC
PRVVDYQKVLSGEVTVGNTVALIGAGGIGFDMAHFLCERQSSTLNADKWLQQWGIDKTYQ
CCEECHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
HAGGLTEPHSDNTDHRKVFLLQRKTSKMGKGLGKTTGWIHRLVLKQHDVKMKTGVSYDKF
HCCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCC
DYAGLHIRVGETAEVLAVDNVVLCAGQESNRTLVDEMKATGLPVHLIGGVDVAAELDAKR
CCCEEEEEECCCEEEEEECCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC
>Mature Secondary Structure 
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEVMGSEGYLINQFVSARTNTR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDEWGGAFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
CCHHCCHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVSILNTGIGWHEARVPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHHVVLFEAKSEVGGQFNLARKIP
HHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFINQINLHKVELRLNTRLDASVLATEKFDEVVIASGVVPRDLVLPGFDD
CHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCC
PRVVDYQKVLSGEVTVGNTVALIGAGGIGFDMAHFLCERQSSTLNADKWLQQWGIDKTYQ
CCEECHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
HAGGLTEPHSDNTDHRKVFLLQRKTSKMGKGLGKTTGWIHRLVLKQHDVKMKTGVSYDKF
HCCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCC
DYAGLHIRVGETAEVLAVDNVVLCAGQESNRTLVDEMKATGLPVHLIGGVDVAAELDAKR
CCCEEEEEECCCEEEEEECCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]