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The map label for this gene is sbcB [H]

Identifier: 126173926

GI number: 126173926

Start: 1975062

End: 1976480

Strand: Reverse

Name: sbcB [H]

Synonym: Sbal_1695

Alternate gene names: 126173926

Gene position: 1976480-1975062 (Counterclockwise)

Preceding gene: 126173933

Following gene: 126173925

Centisome position: 38.55

GC content: 44.82

Gene sequence:

>1419_bases
ATGAAGATGAAAGACGATAAAGCTGGGTCGATTTTTTGGCACGACTACGAAACCTTTGGGGCTAACCCGGCGAAAGACAG
ACCCTCGCAATTTGCCGGTATTCGAACGGATTTAGATCTCAATATTATCGGCGAGCCTGAGACATTTTATTGCAAGCAAG
CCCCTGATTATTTGCCGTCACCAGAAGCGATATTGATCACAGGGATCACTCCGCAGTTAGCCAATTTAAAAGGCATCCCT
GAAACTGAGTTTATGGGGCGTATTCAAGCACTGTTTAGCCAGCCAAACACCTGTGTCGCGGGCTACAACTCACTGCGTTT
TGATGATGAAGTGACCCGTTATGGCTTTTATAGAAACTTTATCGATCCCTATGCCCGTGAATGGCAAAATGGCAACTCTC
GTTGGGATATCATTGATTTAGTACGCGCGTGTTACGCATTTAGACCCGAAGGGATCAATTGGCCAACCAAGGAAGATGGA
TCTCCTAGTTTTAAGCTAGAACATTTGACCCAAGCGAATGGTTTAAGCCATGAGAAAGCCCATGATGCCATGTCTGATGT
GTATGCAACCATCGCTATGGCAAAACTCATTCGCGAGAAACAACCTAAGTTATATCAGTACTATTTTGACCTGCGCCGTA
AGCAAGCGGTGAGCGATCAAATCGATGTGCTCAATATGCAGCCGTTAGTACACGTGAGCTCTAAGATCAGTGCTCGCAAT
GGCTGTACGACGTTGATTTCCCCCGTGGCGCACCATCCAACCAATAAAAATGCAGTTATTTGCGTTAATTTAGCCATGGA
TTTAACGCCACTCTTTGAGCTAGATATCGAGCAAATTAAAACGCGTATGTATACGCCAAGAGCCGATCTTGCCGAAGACG
AATTACCGATCGCGGTAAAACAAATTCATTTAAATAAGTGCCCTTTTATCACTTCGGCTAAAATCCTCAGCGATGAACAT
GCCGCTCGTTTAGGCATAGATAAAGAATTTGCCAGAGAGCAATATAAACGCCTTAAACTTCACCCAGAACTACGTGAAAA
ACTGGCGCTATTATTTGAGCACGATGACAGCAGAGCGACCACAGATCCCGATTTGATGCTCTATTCAGGTGGTTTCTTTA
GCCAAGCTGATAAAGCGAAAATGGAAATCATCCGTCATACCCTACCGCAAAATTTAGCGGCGCTAGACTTGCAGTTTGAT
GATCCACGTATCCCTGAAATGCTGTTTCGTTACCGCGCCCGTAATTACCCTGAACTACTCGATTACGAAGAGTCGCAGCG
CTGGCGTGAATTCTGTCAAAGTCGCTTAGCCGATCAAGACTACGTACTTAAATTAGAAAATCTGCTGCAAGATACGCAAG
TGGATGAGACTAAGCAGAAGTTACTGGCTGCCCTTTGTCATTATTTGCGTGAACTTTAA

Upstream 100 bases:

>100_bases
CGAAGAGTAGCAAACTAAATTGATGTGAATGACAACGAATCCAAATAAAGTCATTTGACGTTAAATAACATGATGTTAAA
TGCTTTAGAGAACGAAATAA

Downstream 100 bases:

>100_bases
GTTTAATCAATTCAAGCTTAAGTCTTTTATTTAATAGTCTTAAGCTTGTTTATATTCGTGAATAGACTCACTCTATTAGG
CGCATAACTTAAATTGTTTA

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKMKDDKAGSIFWHDYETFGANPAKDRPSQFAGIRTDLDLNIIGEPETFYCKQAPDYLPSPEAILITGITPQLANLKGIP
ETEFMGRIQALFSQPNTCVAGYNSLRFDDEVTRYGFYRNFIDPYAREWQNGNSRWDIIDLVRACYAFRPEGINWPTKEDG
SPSFKLEHLTQANGLSHEKAHDAMSDVYATIAMAKLIREKQPKLYQYYFDLRRKQAVSDQIDVLNMQPLVHVSSKISARN
GCTTLISPVAHHPTNKNAVICVNLAMDLTPLFELDIEQIKTRMYTPRADLAEDELPIAVKQIHLNKCPFITSAKILSDEH
AARLGIDKEFAREQYKRLKLHPELREKLALLFEHDDSRATTDPDLMLYSGGFFSQADKAKMEIIRHTLPQNLAALDLQFD
DPRIPEMLFRYRARNYPELLDYEESQRWREFCQSRLADQDYVLKLENLLQDTQVDETKQKLLAALCHYLREL

Sequences:

>Translated_472_residues
MKMKDDKAGSIFWHDYETFGANPAKDRPSQFAGIRTDLDLNIIGEPETFYCKQAPDYLPSPEAILITGITPQLANLKGIP
ETEFMGRIQALFSQPNTCVAGYNSLRFDDEVTRYGFYRNFIDPYAREWQNGNSRWDIIDLVRACYAFRPEGINWPTKEDG
SPSFKLEHLTQANGLSHEKAHDAMSDVYATIAMAKLIREKQPKLYQYYFDLRRKQAVSDQIDVLNMQPLVHVSSKISARN
GCTTLISPVAHHPTNKNAVICVNLAMDLTPLFELDIEQIKTRMYTPRADLAEDELPIAVKQIHLNKCPFITSAKILSDEH
AARLGIDKEFAREQYKRLKLHPELREKLALLFEHDDSRATTDPDLMLYSGGFFSQADKAKMEIIRHTLPQNLAALDLQFD
DPRIPEMLFRYRARNYPELLDYEESQRWREFCQSRLADQDYVLKLENLLQDTQVDETKQKLLAALCHYLREL
>Mature_472_residues
MKMKDDKAGSIFWHDYETFGANPAKDRPSQFAGIRTDLDLNIIGEPETFYCKQAPDYLPSPEAILITGITPQLANLKGIP
ETEFMGRIQALFSQPNTCVAGYNSLRFDDEVTRYGFYRNFIDPYAREWQNGNSRWDIIDLVRACYAFRPEGINWPTKEDG
SPSFKLEHLTQANGLSHEKAHDAMSDVYATIAMAKLIREKQPKLYQYYFDLRRKQAVSDQIDVLNMQPLVHVSSKISARN
GCTTLISPVAHHPTNKNAVICVNLAMDLTPLFELDIEQIKTRMYTPRADLAEDELPIAVKQIHLNKCPFITSAKILSDEH
AARLGIDKEFAREQYKRLKLHPELREKLALLFEHDDSRATTDPDLMLYSGGFFSQADKAKMEIIRHTLPQNLAALDLQFD
DPRIPEMLFRYRARNYPELLDYEESQRWREFCQSRLADQDYVLKLENLLQDTQVDETKQKLLAALCHYLREL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=475, Percent_Identity=52.8421052631579, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54493; Mature: 54493

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKDDKAGSIFWHDYETFGANPAKDRPSQFAGIRTDLDLNIIGEPETFYCKQAPDYLPS
CCCCCCCCCCEEEECHHHCCCCCCCCCCHHHCCCEECCEEEEECCCCCEEECCCCCCCCC
PEAILITGITPQLANLKGIPETEFMGRIQALFSQPNTCVAGYNSLRFDDEVTRYGFYRNF
CCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
IDPYAREWQNGNSRWDIIDLVRACYAFRPEGINWPTKEDGSPSFKLEHLTQANGLSHEKA
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHH
HDAMSDVYATIAMAKLIREKQPKLYQYYFDLRRKQAVSDQIDVLNMQPLVHVSSKISARN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GCTTLISPVAHHPTNKNAVICVNLAMDLTPLFELDIEQIKTRMYTPRADLAEDELPIAVK
CCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
QIHLNKCPFITSAKILSDEHAARLGIDKEFAREQYKRLKLHPELREKLALLFEHDDSRAT
HEECCCCCCCCHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
TDPDLMLYSGGFFSQADKAKMEIIRHTLPQNLAALDLQFDDPRIPEMLFRYRARNYPELL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHH
DYEESQRWREFCQSRLADQDYVLKLENLLQDTQVDETKQKLLAALCHYLREL
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKMKDDKAGSIFWHDYETFGANPAKDRPSQFAGIRTDLDLNIIGEPETFYCKQAPDYLPS
CCCCCCCCCCEEEECHHHCCCCCCCCCCHHHCCCEECCEEEEECCCCCEEECCCCCCCCC
PEAILITGITPQLANLKGIPETEFMGRIQALFSQPNTCVAGYNSLRFDDEVTRYGFYRNF
CCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
IDPYAREWQNGNSRWDIIDLVRACYAFRPEGINWPTKEDGSPSFKLEHLTQANGLSHEKA
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHH
HDAMSDVYATIAMAKLIREKQPKLYQYYFDLRRKQAVSDQIDVLNMQPLVHVSSKISARN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GCTTLISPVAHHPTNKNAVICVNLAMDLTPLFELDIEQIKTRMYTPRADLAEDELPIAVK
CCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
QIHLNKCPFITSAKILSDEHAARLGIDKEFAREQYKRLKLHPELREKLALLFEHDDSRAT
HEECCCCCCCCHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
TDPDLMLYSGGFFSQADKAKMEIIRHTLPQNLAALDLQFDDPRIPEMLFRYRARNYPELL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHH
DYEESQRWREFCQSRLADQDYVLKLENLLQDTQVDETKQKLLAALCHYLREL
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]