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The map label for this gene is 126173778

Identifier: 126173778

GI number: 126173778

Start: 1796398

End: 1796793

Strand: Reverse

Name: 126173778

Synonym: Sbal_1544

Alternate gene names: NA

Gene position: 1796793-1796398 (Counterclockwise)

Preceding gene: 126173782

Following gene: 126173777

Centisome position: 35.04

GC content: 47.98

Gene sequence:

>396_bases
ATGCGCGTAACCCGCTTAGATCATTTGGTCTTAACCGTAAAAGACATCGCCGTCAGCGTCGAATTTTATCAAACCGTGCT
CGGGATGAAGAAAGTGGTATTTGGCAATCAGCGTATTGCGTTAAGTTTTGGCGACCAAAAGATTAATCTGCACCAAGCGG
GCGCCGAATTTGAACCTAAAGCTGCAGCAGCCACGCCCGGCAGTGCCGATCTATGTTTTGTAGTCAGCCATAACATAGAA
GAAGTGATCGCGCATTTAAACGCTCTTCAGATTAAAATCATTGAAGGACCAGTGCTACGAACCGGCGCCACAGGCCGGAT
AAACTCTGTCTATATCCGCGACCCCGATTGTAACCTGCTTGAGTTATCAGAATATTTGCCCGCCTGCACTGGGTAA

Upstream 100 bases:

>100_bases
CACCAGCACATGATGTAAGGTATCTGACTCTTATTCGTCTCAAGCATAGAGATAGCGTTCAAAATCAGAGCCCACTCTGA
GCCATTCTAAGGAAAGTAAA

Downstream 100 bases:

>100_bases
GCGAAGTTAAAAACTTCATTTGAATTTTTTAATCAAAGTCAAAGTCGTGGGGCTTCACCCCACACCCGACCAAGGAGGAC
TGCTCGTCCTATCAAAAACG

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MRVTRLDHLVLTVKDIAVSVEFYQTVLGMKKVVFGNQRIALSFGDQKINLHQAGAEFEPKAAAATPGSADLCFVVSHNIE
EVIAHLNALQIKIIEGPVLRTGATGRINSVYIRDPDCNLLELSEYLPACTG

Sequences:

>Translated_131_residues
MRVTRLDHLVLTVKDIAVSVEFYQTVLGMKKVVFGNQRIALSFGDQKINLHQAGAEFEPKAAAATPGSADLCFVVSHNIE
EVIAHLNALQIKIIEGPVLRTGATGRINSVYIRDPDCNLLELSEYLPACTG
>Mature_131_residues
MRVTRLDHLVLTVKDIAVSVEFYQTVLGMKKVVFGNQRIALSFGDQKINLHQAGAEFEPKAAAATPGSADLCFVVSHNIE
EVIAHLNALQIKIIEGPVLRTGATGRINSVYIRDPDCNLLELSEYLPACTG

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=124, Percent_Identity=54.0322580645161, Blast_Score=145, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14277; Mature: 14277

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTRLDHLVLTVKDIAVSVEFYQTVLGMKKVVFGNQRIALSFGDQKINLHQAGAEFEPK
CCCCCHHHEEEEEEHHEEHHHHHHHHHHHHHHEECCCEEEEEECCCEEEEEECCCCCCCC
AAAATPGSADLCFVVSHNIEEVIAHLNALQIKIIEGPVLRTGATGRINSVYIRDPDCNLL
CCCCCCCCCCEEEEEECCHHHHHHHCCEEEEEEECCCEEECCCCCCCEEEEEECCCCCEE
ELSEYLPACTG
EHHHHCCCCCC
>Mature Secondary Structure
MRVTRLDHLVLTVKDIAVSVEFYQTVLGMKKVVFGNQRIALSFGDQKINLHQAGAEFEPK
CCCCCHHHEEEEEEHHEEHHHHHHHHHHHHHHEECCCEEEEEECCCEEEEEECCCCCCCC
AAAATPGSADLCFVVSHNIEEVIAHLNALQIKIIEGPVLRTGATGRINSVYIRDPDCNLL
CCCCCCCCCCEEEEEECCHHHHHHHCCEEEEEEECCCEEECCCCCCCEEEEEECCCCCEE
ELSEYLPACTG
EHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]