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The map label for this gene is cynX [H]

Identifier: 126173637

GI number: 126173637

Start: 1609412

End: 1610617

Strand: Reverse

Name: cynX [H]

Synonym: Sbal_1399

Alternate gene names: 126173637

Gene position: 1610617-1609412 (Counterclockwise)

Preceding gene: 126173640

Following gene: 126173634

Centisome position: 31.41

GC content: 50.08

Gene sequence:

>1206_bases
ATGCGGTCACCCCAGTCAGAGAAAGCGAATTTATTACTTCTCGGAATCGCGTTCATTCTTATCGGTCTAAATCTGCGCCC
CATTCTCGCTTCCGTCGGGCCTTTGCTGCCCAGCATACAAGAGGATATCAGCTTAAGTTTTACCCTAGCGTCTATGCTGA
CATTGCTGCCCGTGCTCGCCATGGGACTGGGCTGCTTTGCGGGTTTTAGTATCGCTAAACGGTTAGGTTTTAATACCGTG
ATGACGGGATCGTTGCTCCTCTTGATCGTCGCCACGGCAATGCGTTTTTGGGCGATGGATGCAAGCTGGCTTATCTGCTC
GGCATTACTAGCCGGAGTCGGTATCGCTCTTATTCAAACCATCATGCCTGCCATGATCAAACTCAATTTCGGTGAACGGG
TGCCCTTAATGATGGGGCTTTACGTCACCGCCATTATGGGCGGCGCTGCTTTGGCCGCCAGCAGTGCGCCTTTTATCGGG
ATGAACTTAGGTTGGCGTGCGGGCTTAGGCCATTGGACTTGGTTAGGCGTAGTGGCACTGGCGCTATGGCTGATGGTTAA
ACATAACGCCGCATTGCCGAATCAAACTGCGGAGCAAACTGTGCAGCTTAGCTTTTGGCGTTTTCGTCGCAGTTGGCTAT
TAGCGATATTTTTTGCTTTAGGCACAAGCTGTTATGTCTGCGTGCTTGCATGGTTAGCCCCCTACGCGGTCGAGTTAGGT
TATAGCCAAACGCAATCGGGATTAGTGTTAGGTTTCTTAACCAGCATGGAAGTGATCGCGGGCTTAGTGTTTCCTTGGCT
TGCCAGCAAGTCAACGGACAGACGCGCTATTATTGCCCTACTGTGCTTACTGCAACTCATCGGTTTTATGGGGCTCGCAC
TCGCCCCTCAAGTGTCGCTATTTTTATGGGCGGGACTTGCGGGATTAGGCATAGGCGGGATTTTTCCACTCGGATTAATT
GTGACTATGGATCATCAACAAAATCCGATGTTAGCGGGTAAATTAACCGCCTTTGTACAAGGTGTGGGTTATACCATTGC
CGCCATTTCGCCTTGGATTGCTGGATTGATCCGCGATAATTTCAATAGCTTTAACAGTGCATGGTTGTTGCTCGGGGGCT
TAAGTCTGATGGCGTGGATACTATCTTGGCAATTTAATCCGCAGGGTTATGCACGCCAATATCAAGTCACCCGCTGCGTA
TCTTAA

Upstream 100 bases:

>100_bases
CAACTTACTGTAGTTGAAAGGAAATCATCGTAAATGTGCTAAATGCCGCTACAGGTCACTCTTTCAACAAATCAAACTTA
GCTTATTTTGGAGACAATCC

Downstream 100 bases:

>100_bases
CTCTCTAATTCAAAATAAAAAAACCGCCATGTCGATTAACGAGCATGGCGGTTTTTTATAGTGTGGGCTCGATAAATCGA
GCCCACACTAGGTACAACTT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRSPQSEKANLLLLGIAFILIGLNLRPILASVGPLLPSIQEDISLSFTLASMLTLLPVLAMGLGCFAGFSIAKRLGFNTV
MTGSLLLLIVATAMRFWAMDASWLICSALLAGVGIALIQTIMPAMIKLNFGERVPLMMGLYVTAIMGGAALAASSAPFIG
MNLGWRAGLGHWTWLGVVALALWLMVKHNAALPNQTAEQTVQLSFWRFRRSWLLAIFFALGTSCYVCVLAWLAPYAVELG
YSQTQSGLVLGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGLALAPQVSLFLWAGLAGLGIGGIFPLGLI
VTMDHQQNPMLAGKLTAFVQGVGYTIAAISPWIAGLIRDNFNSFNSAWLLLGGLSLMAWILSWQFNPQGYARQYQVTRCV
S

Sequences:

>Translated_401_residues
MRSPQSEKANLLLLGIAFILIGLNLRPILASVGPLLPSIQEDISLSFTLASMLTLLPVLAMGLGCFAGFSIAKRLGFNTV
MTGSLLLLIVATAMRFWAMDASWLICSALLAGVGIALIQTIMPAMIKLNFGERVPLMMGLYVTAIMGGAALAASSAPFIG
MNLGWRAGLGHWTWLGVVALALWLMVKHNAALPNQTAEQTVQLSFWRFRRSWLLAIFFALGTSCYVCVLAWLAPYAVELG
YSQTQSGLVLGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGLALAPQVSLFLWAGLAGLGIGGIFPLGLI
VTMDHQQNPMLAGKLTAFVQGVGYTIAAISPWIAGLIRDNFNSFNSAWLLLGGLSLMAWILSWQFNPQGYARQYQVTRCV
S
>Mature_401_residues
MRSPQSEKANLLLLGIAFILIGLNLRPILASVGPLLPSIQEDISLSFTLASMLTLLPVLAMGLGCFAGFSIAKRLGFNTV
MTGSLLLLIVATAMRFWAMDASWLICSALLAGVGIALIQTIMPAMIKLNFGERVPLMMGLYVTAIMGGAALAASSAPFIG
MNLGWRAGLGHWTWLGVVALALWLMVKHNAALPNQTAEQTVQLSFWRFRRSWLLAIFFALGTSCYVCVLAWLAPYAVELG
YSQTQSGLVLGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGLALAPQVSLFLWAGLAGLGIGGIFPLGLI
VTMDHQQNPMLAGKLTAFVQGVGYTIAAISPWIAGLIRDNFNSFNSAWLLLGGLSLMAWILSWQFNPQGYARQYQVTRCV
S

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=355, Percent_Identity=38.5915492957746, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788092, Length=356, Percent_Identity=28.6516853932584, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43221; Mature: 43221

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPQSEKANLLLLGIAFILIGLNLRPILASVGPLLPSIQEDISLSFTLASMLTLLPVLA
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MGLGCFAGFSIAKRLGFNTVMTGSLLLLIVATAMRFWAMDASWLICSALLAGVGIALIQT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IMPAMIKLNFGERVPLMMGLYVTAIMGGAALAASSAPFIGMNLGWRAGLGHWTWLGVVAL
HHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHH
ALWLMVKHNAALPNQTAEQTVQLSFWRFRRSWLLAIFFALGTSCYVCVLAWLAPYAVELG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSQTQSGLVLGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGLALAPQVSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLWAGLAGLGIGGIFPLGLIVTMDHQQNPMLAGKLTAFVQGVGYTIAAISPWIAGLIRDN
HHHHHHHHCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
FNSFNSAWLLLGGLSLMAWILSWQFNPQGYARQYQVTRCVS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRSPQSEKANLLLLGIAFILIGLNLRPILASVGPLLPSIQEDISLSFTLASMLTLLPVLA
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MGLGCFAGFSIAKRLGFNTVMTGSLLLLIVATAMRFWAMDASWLICSALLAGVGIALIQT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IMPAMIKLNFGERVPLMMGLYVTAIMGGAALAASSAPFIGMNLGWRAGLGHWTWLGVVAL
HHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHH
ALWLMVKHNAALPNQTAEQTVQLSFWRFRRSWLLAIFFALGTSCYVCVLAWLAPYAVELG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSQTQSGLVLGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGLALAPQVSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLWAGLAGLGIGGIFPLGLIVTMDHQQNPMLAGKLTAFVQGVGYTIAAISPWIAGLIRDN
HHHHHHHHCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
FNSFNSAWLLLGGLSLMAWILSWQFNPQGYARQYQVTRCVS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]