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The map label for this gene is yiaY [H]

Identifier: 126173559

GI number: 126173559

Start: 1504427

End: 1505575

Strand: Reverse

Name: yiaY [H]

Synonym: Sbal_1321

Alternate gene names: 126173559

Gene position: 1505575-1504427 (Counterclockwise)

Preceding gene: 126173560

Following gene: 126173558

Centisome position: 29.36

GC content: 50.13

Gene sequence:

>1149_bases
ATGGCTGCTAAATTTTTTATTCCTTCTGTCAACGTGTTAGGCCAAGGCGCAGTGGATGACGCTATCGGTGACATCAAAAC
CTTAGGCTTTAAACACGCACTCATAGTGACAGACAAACCCTTAGTCAAAATTGGCTTAGTCGGTGAAGTGGCCGAAAAAC
TTGGTCAAAATGGCATTACCTCCACCATCTATGATGGCGTACAACCTAACCCAACCGTAACGAACGTCGAAGCAGGTTTA
GCCCTGTTAAAAGCCAACAAGTGTGACTTTGTGATTTCACTCGGTGGCGGCTCACCCCATGATTGCGCCAAAGGTATCGC
CCTTGTTGCCACCAATGGCGGCAGCATTAAGGATTACGAAGGGTTAGATCAATCCGCAAAACCACAGTTGCCATTAGTGG
CTATTAATACGACGGCAGGTACTGCCAGTGAAATGACGCGCTTCTGTATCATTACCGACGAAGCCCGCCACATTAAAATG
GCGATTGTCGATAAGCACACCACGCCTTTGCTGTCGGTCAATGACCCTGAACTCATGCTGAAAAAGCCTGCGAGCCTCAC
GGCCGCAACCGGTATGGATGCACTGACTCACGCGGTTGAAGCCTATGTGTCTATTGCTGCCAACCCGATCACCGACGCCT
GCGCGATCAAGGCTATGGAATTGATTCAGGCTAACTTAGTCAACGCGGTTGAAAACGGTCAAGACATCAATGCCCGTGAA
CAAATGGCCTACGCACAGTTCTTAGCGGGTATGGCCTTTAACAATGCCAGCTTAGGTTATGTGCATGCGATGGCGCACCA
GTTAGGCGGTTTCTACGATCTGCCCCACGGTGTGTGTAACGCCCTGCTGCTGCCCCATGTACAGGAATACAACGCCCAGG
TCGTCCCTGCTCGCTTGAAAGACATTGCCAAGGCTATGGGTGTGGATGTGTCCAGCATGACCGATGAGCAAGGTGCCAGT
GCGGCGATAGCGGCAATCAAAAAGCTGTCTTTTGCGGTTAAGATCCCAGAAAACCTGACCTTGTTAGGCGTAAAAGCGGA
AGATATTCCAACACTTGCGGATAACGCGTTAAAAGATGCCTGTGGATTCACCAATCCAAAACAAGCGACCCAAGCGGAGA
TCTGTCAGATCTTCACTAATGCGCTGTAG

Upstream 100 bases:

>100_bases
CCGAACTCGATCGAGCTCACACTTTCACTACCTCCAAATTGGTAGCTTGATCACCAGAAAAGAACACAACTTAATCTTTA
CAAGCAAATAGGTGGATTTT

Downstream 100 bases:

>100_bases
TTGCGCGCTGTAATCGCCATACTTTATCAATCGCAAGTTATCGCACAGCAATCGTGCGCTAACTTGCTGGATAACGACTG
ATTGTCCTGCTAGTGCGTAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAAKFFIPSVNVLGQGAVDDAIGDIKTLGFKHALIVTDKPLVKIGLVGEVAEKLGQNGITSTIYDGVQPNPTVTNVEAGL
ALLKANKCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAMELIQANLVNAVENGQDINARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVVPARLKDIAKAMGVDVSSMTDEQGAS
AAIAAIKKLSFAVKIPENLTLLGVKAEDIPTLADNALKDACGFTNPKQATQAEICQIFTNAL

Sequences:

>Translated_382_residues
MAAKFFIPSVNVLGQGAVDDAIGDIKTLGFKHALIVTDKPLVKIGLVGEVAEKLGQNGITSTIYDGVQPNPTVTNVEAGL
ALLKANKCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAMELIQANLVNAVENGQDINARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVVPARLKDIAKAMGVDVSSMTDEQGAS
AAIAAIKKLSFAVKIPENLTLLGVKAEDIPTLADNALKDACGFTNPKQATQAEICQIFTNAL
>Mature_381_residues
AAKFFIPSVNVLGQGAVDDAIGDIKTLGFKHALIVTDKPLVKIGLVGEVAEKLGQNGITSTIYDGVQPNPTVTNVEAGLA
LLKANKCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMA
IVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAMELIQANLVNAVENGQDINAREQ
MAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVVPARLKDIAKAMGVDVSSMTDEQGASA
AIAAIKKLSFAVKIPENLTLLGVKAEDIPTLADNALKDACGFTNPKQATQAEICQIFTNAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=387, Percent_Identity=29.4573643410853, Blast_Score=145, Evalue=8e-35,
Organism=Escherichia coli, GI48994951, Length=381, Percent_Identity=69.0288713910761, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=44.0104166666667, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=37.1352785145889, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787493, Length=407, Percent_Identity=31.2039312039312, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789386, Length=323, Percent_Identity=25.077399380805, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=410, Percent_Identity=24.6341463414634, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=54.6174142480211, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=26.8292682926829, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40032; Mature: 39900

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKFFIPSVNVLGQGAVDDAIGDIKTLGFKHALIVTDKPLVKIGLVGEVAEKLGQNGIT
CCCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEHHHHHHHHHCCCCCC
STIYDGVQPNPTVTNVEAGLALLKANKCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHHCCCCCCCCEEEHHHCEEEEECCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCCC
GLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLLSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHEE
KKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAMELIQANLVNAVENGQDINARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVVPARLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DIAKAMGVDVSSMTDEQGASAAIAAIKKLSFAVKIPENLTLLGVKAEDIPTLADNALKDA
HHHHHHCCCHHHCCCCCCHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHHHHHH
CGFTNPKQATQAEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAKFFIPSVNVLGQGAVDDAIGDIKTLGFKHALIVTDKPLVKIGLVGEVAEKLGQNGIT
CCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEHHHHHHHHHCCCCCC
STIYDGVQPNPTVTNVEAGLALLKANKCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHHCCCCCCCCEEEHHHCEEEEECCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCCC
GLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLLSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHEE
KKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAMELIQANLVNAVENGQDINARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVVPARLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DIAKAMGVDVSSMTDEQGASAAIAAIKKLSFAVKIPENLTLLGVKAEDIPTLADNALKDA
HHHHHHCCCHHHCCCCCCHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHHHHHH
CGFTNPKQATQAEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]