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The map label for this gene is ugd [H]

Identifier: 125624416

GI number: 125624416

Start: 1587913

End: 1589082

Strand: Reverse

Name: ugd [H]

Synonym: llmg_1616

Alternate gene names: 125624416

Gene position: 1589082-1587913 (Counterclockwise)

Preceding gene: 125624417

Following gene: 125624415

Centisome position: 62.82

GC content: 38.03

Gene sequence:

>1170_bases
ATGACTAAAATAGCAGTAGTCGGTGCTGGTTATGTAGGAATGTCAATGGCAACTCTCCTTGCTCAAGGCAATGAAGTTCA
AATCGTGGATATTATTGCCGACAAGGTTAATAAAATCAATCAGAAAATCTCACCAATCAAAGATGAAGTTATTCAAGATT
TTTTATCTAACCATACACTAAATTTAAAAGCAACACTTGACAGCAGGCAAGCAATCAAAGATGCAAGTTTCGTGATTATT
GCAGCTCCAACAAATTATGACCCAGATAAACATTACTTTGATACCTCAGCTGTTGATGCGGTCATTGAAGAAACGGTAAA
AATTAATCCTAGTGCGCTCATGATTATTAAATCAACGATTCCAGTTGGCTATACAGAGGCAACCAAAAAGAAATATCAGA
CAGAAAACCTTATTTTTAGTCCAGAATTTCTAAGAGAAGGTAAAGCTTTGTATGATAATCTCCACCCAAGCCGTGTGATT
GTCGGCGAGAAGAGTTCGCGTGCCCATGAGTTTGCTAGACTCCTGATTGAGGGAGCGATTGATAAAGATATTCCTGCTTT
ATTTGTAAGCAGCCCTGAGGCAGAAGCAATCAAACTTTTTGCTAATACCTACCTTGCGATGCGCGTGGCTTTCTTTAATG
AACTTGATACTTATGCCGAAAAAAATCAATTAAATAGTCAACATATTATTAACGGTGTTGGGTTGGATTCACGGATTGGG
ACACATAATAATAATCCAAGTTTTGGTTATGGTGGTTATTGTTTGCCGAAAGACTCAAAGCAGCTTTTGGCCAGTTATGA
GGGCGTTCCTCAGGAGTTGATGACGGCTATTGTCAATACAAACGAAACCAGAAAACAGCACATTGTTGAGCAGATTATGG
CTAAATCTCAAAAAACTGTTGGAATTTACCGGTTGGTCATGAAAGCTGGGTCAGATAATTTCAGACAGAGTTCGATTATT
GATGTGATGAAACTCTTGCAAGATAAGGGGATAACGGTTCTTATCTATGAACCTACACTAGATTTGAAAGATTATGAAGG
GGCAAAACTCTTAGCAGATTTTGCTGACTTTAAAGAAAAAAGTGATGTGATTATCGCAAACCGGATGACAGAGGAATTAA
AAGCTGTGGACTCAAAAGTTTATACGAGAGATTTGTATAGAAGGGACTAG

Upstream 100 bases:

>100_bases
CAGTCCTCCCTAAAGATGCTCAATTTATCAAAGAAGTACAAGGATAAAATTTAGATAAAGCTAATAATCAAAAACATTAG
AAGAAAGTCAGGGAAAAAAG

Downstream 100 bases:

>100_bases
ATTGGAATAAACGATGAACCGTTATTACCTTGTAAAAGAAGATGGCACAAAAATAGAAAATCCCAAGATTAATGGCCTAA
CTGTTGAATTTTTAGGAAAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTKIAVVGAGYVGMSMATLLAQGNEVQIVDIIADKVNKINQKISPIKDEVIQDFLSNHTLNLKATLDSRQAIKDASFVII
AAPTNYDPDKHYFDTSAVDAVIEETVKINPSALMIIKSTIPVGYTEATKKKYQTENLIFSPEFLREGKALYDNLHPSRVI
VGEKSSRAHEFARLLIEGAIDKDIPALFVSSPEAEAIKLFANTYLAMRVAFFNELDTYAEKNQLNSQHIINGVGLDSRIG
THNNNPSFGYGGYCLPKDSKQLLASYEGVPQELMTAIVNTNETRKQHIVEQIMAKSQKTVGIYRLVMKAGSDNFRQSSII
DVMKLLQDKGITVLIYEPTLDLKDYEGAKLLADFADFKEKSDVIIANRMTEELKAVDSKVYTRDLYRRD

Sequences:

>Translated_389_residues
MTKIAVVGAGYVGMSMATLLAQGNEVQIVDIIADKVNKINQKISPIKDEVIQDFLSNHTLNLKATLDSRQAIKDASFVII
AAPTNYDPDKHYFDTSAVDAVIEETVKINPSALMIIKSTIPVGYTEATKKKYQTENLIFSPEFLREGKALYDNLHPSRVI
VGEKSSRAHEFARLLIEGAIDKDIPALFVSSPEAEAIKLFANTYLAMRVAFFNELDTYAEKNQLNSQHIINGVGLDSRIG
THNNNPSFGYGGYCLPKDSKQLLASYEGVPQELMTAIVNTNETRKQHIVEQIMAKSQKTVGIYRLVMKAGSDNFRQSSII
DVMKLLQDKGITVLIYEPTLDLKDYEGAKLLADFADFKEKSDVIIANRMTEELKAVDSKVYTRDLYRRD
>Mature_388_residues
TKIAVVGAGYVGMSMATLLAQGNEVQIVDIIADKVNKINQKISPIKDEVIQDFLSNHTLNLKATLDSRQAIKDASFVIIA
APTNYDPDKHYFDTSAVDAVIEETVKINPSALMIIKSTIPVGYTEATKKKYQTENLIFSPEFLREGKALYDNLHPSRVIV
GEKSSRAHEFARLLIEGAIDKDIPALFVSSPEAEAIKLFANTYLAMRVAFFNELDTYAEKNQLNSQHIINGVGLDSRIGT
HNNNPSFGYGGYCLPKDSKQLLASYEGVPQELMTAIVNTNETRKQHIVEQIMAKSQKTVGIYRLVMKAGSDNFRQSSIID
VMKLLQDKGITVLIYEPTLDLKDYEGAKLLADFADFKEKSDVIIANRMTEELKAVDSKVYTRDLYRRD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=372, Percent_Identity=25.8064516129032, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI296040443, Length=355, Percent_Identity=23.0985915492958, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI296040438, Length=243, Percent_Identity=25.5144032921811, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788340, Length=387, Percent_Identity=59.9483204134367, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI48994968, Length=413, Percent_Identity=23.9709443099274, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560350, Length=416, Percent_Identity=26.4423076923077, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136908, Length=379, Percent_Identity=27.1767810026385, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43413; Mature: 43282

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAVVGAGYVGMSMATLLAQGNEVQIVDIIADKVNKINQKISPIKDEVIQDFLSNHTL
CCEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCE
NLKATLDSRQAIKDASFVIIAAPTNYDPDKHYFDTSAVDAVIEETVKINPSALMIIKSTI
EEEEECCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCEEEEEEECC
PVGYTEATKKKYQTENLIFSPEFLREGKALYDNLHPSRVIVGEKSSRAHEFARLLIEGAI
CCCCCHHHHHHHHCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
DKDIPALFVSSPEAEAIKLFANTYLAMRVAFFNELDTYAEKNQLNSQHIINGVGLDSRIG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCC
THNNNPSFGYGGYCLPKDSKQLLASYEGVPQELMTAIVNTNETRKQHIVEQIMAKSQKTV
CCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
GIYRLVMKAGSDNFRQSSIIDVMKLLQDKGITVLIYEPTLDLKDYEGAKLLADFADFKEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCC
SDVIIANRMTEELKAVDSKVYTRDLYRRD
CCEEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKIAVVGAGYVGMSMATLLAQGNEVQIVDIIADKVNKINQKISPIKDEVIQDFLSNHTL
CEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCE
NLKATLDSRQAIKDASFVIIAAPTNYDPDKHYFDTSAVDAVIEETVKINPSALMIIKSTI
EEEEECCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCEEEEEEECC
PVGYTEATKKKYQTENLIFSPEFLREGKALYDNLHPSRVIVGEKSSRAHEFARLLIEGAI
CCCCCHHHHHHHHCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
DKDIPALFVSSPEAEAIKLFANTYLAMRVAFFNELDTYAEKNQLNSQHIINGVGLDSRIG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCC
THNNNPSFGYGGYCLPKDSKQLLASYEGVPQELMTAIVNTNETRKQHIVEQIMAKSQKTV
CCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
GIYRLVMKAGSDNFRQSSIIDVMKLLQDKGITVLIYEPTLDLKDYEGAKLLADFADFKEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCC
SDVIIANRMTEELKAVDSKVYTRDLYRRD
CCEEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]