Click here to switch to the map view.

The map label for this gene is trxB1 [H]

Identifier: 125624390

GI number: 125624390

Start: 1563450

End: 1564376

Strand: Reverse

Name: trxB1 [H]

Synonym: llmg_1588

Alternate gene names: 125624390

Gene position: 1564376-1563450 (Counterclockwise)

Preceding gene: 125624391

Following gene: 125624389

Centisome position: 61.85

GC content: 38.51

Gene sequence:

>927_bases
ATGACAGAAAAGAAATATGATGTTGTCATCATTGGTTCAGGCCCTGCGGGAATGACTGCAGCGATGTATACTGCTCGTTC
TGAAATGAAAACTTTGCTTTTAGAGCGTGGTGTTCCTGGCGGTCAAATGAATAATACAGCGGAGATTGAAAACTATCCTG
GTTATGAAACAATCATGGGACCTGAACTTTCAATGAAAATGGCTGAACCTTTGGAAGGTTTGGGAGTTGAAAATGCTTAT
GGTTTTGTGACTGGCATTGAAGATCATGGTGATTATAAAAAAATTATCACCGAAGATGATGAGTTCATCACAAAATCAAT
CATTATCGCGACTGGAGCTAATCACCGTAAGCTAGAAATTCCTGGAGAAGAAGAATATGGAGCTCGTGGAGTTTCTTATT
GTGCCGTTTGTGATGGTGCATTCTTTAGAAACCAAGAAATCTTAGTCATTGGTGGTGGGGATTCGGCCGTTGAAGAAGCA
CTCTATTTGACTCGTTTTGGTCAATCAGTGACGATTATGCATCGTCGTGATAAATTACGTGCACAAGAAATTATTCAACA
AAGAGCTTTTAAAGAAGAAAAAATCAACTTTATTTGGGATTCTGTTCCGATGGAAATCAAAGGAGATGATAAAAAAATTC
AATCTGTTGTTTATAAAAATGTTAAAACAGGTGAAGTAACTGAAAAAGCTTTTGGTGGAATATTCATTTATGTAGGACTT
GATCCAGTAGCTGAATTTGTGAGCGATCTTGGAATTACTGACGAAGCAGGTTGGATTATTACTGACGACCACATGAGGAC
AAATATCCCTGGTATCTTTGCCGTAGGAGATGTTCGTCAAAAGGATTTCCGTCAAATCACAACAGCAGTTGGTGATGGTG
CTCAAGCAGCTCAAGAAGCTTATAAGTTTGTTGTTGAACTTGGATAA

Upstream 100 bases:

>100_bases
TTTTAGATCTGATAAATGAAGAGCTCAAGTTTGCTTAAAAGCTAGCTTGAGTTTATAAATTTAAGGGGAGTTCTTAAGCT
CTTAGAAAAGGGATTAAAAA

Downstream 100 bases:

>100_bases
AATAAAAATTACTGACAAAGAAGTCAGTAATTTTTTGTTAAAGGATTCGGAATGACATTTAATAGAAAATATGGTAAACT
GTAAGTAACACAATTTTGAA

Product: TrxB1 protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAY
GFVTGIEDHGDYKKIITEDDEFITKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEA
LYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGL
DPVAEFVSDLGITDEAGWIITDDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGAQAAQEAYKFVVELG

Sequences:

>Translated_308_residues
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAY
GFVTGIEDHGDYKKIITEDDEFITKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEA
LYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGL
DPVAEFVSDLGITDEAGWIITDDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGAQAAQEAYKFVVELG
>Mature_307_residues
TEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAYG
FVTGIEDHGDYKKIITEDDEFITKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEAL
YLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLD
PVAEFVSDLGITDEAGWIITDDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGAQAAQEAYKFVVELG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI148277071, Length=244, Percent_Identity=27.4590163934426, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI148277065, Length=244, Percent_Identity=27.4590163934426, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI33519430, Length=244, Percent_Identity=27.4590163934426, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI33519428, Length=244, Percent_Identity=27.4590163934426, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI33519426, Length=244, Percent_Identity=27.4590163934426, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI291045266, Length=245, Percent_Identity=24.8979591836735, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI291045268, Length=245, Percent_Identity=24.8979591836735, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=36.624203821656, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=32.3529411764706, Blast_Score=157, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=42.8115015974441, Blast_Score=233, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=38.7820512820513, Blast_Score=204, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24640553, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640549, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640551, Length=212, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33951; Mature: 33820

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMG
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDEFITKSIIIATGANHRKLEI
CCCCHHHHCCHHHCCCCCCCEEEEECCCCCCHHHHCCCCHHHHEEEEEEEECCCCEEEEC
PGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLR
CCCCCCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHH
AQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGL
HHHHHHHHHHHHHCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
DPVAEFVSDLGITDEAGWIITDDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGAQAAQEA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHH
YKFVVELG
HHHHEECC
>Mature Secondary Structure 
TEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMG
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDEFITKSIIIATGANHRKLEI
CCCCHHHHCCHHHCCCCCCCEEEEECCCCCCHHHHCCCCHHHHEEEEEEEECCCCEEEEC
PGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLR
CCCCCCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHH
AQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGL
HHHHHHHHHHHHHCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
DPVAEFVSDLGITDEAGWIITDDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGAQAAQEA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHH
YKFVVELG
HHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]