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The map label for this gene is fruR [H]

Identifier: 125624372

GI number: 125624372

Start: 1543662

End: 1544363

Strand: Reverse

Name: fruR [H]

Synonym: llmg_1570

Alternate gene names: 125624372

Gene position: 1544363-1543662 (Counterclockwise)

Preceding gene: 125624373

Following gene: 125624371

Centisome position: 61.05

GC content: 36.89

Gene sequence:

>702_bases
ATGTTAGTAAATGAAAGAAAAAAAAGGATTGTTGACTATCTAAAAATAAATAGGAGAGCAACAATAGAAGAACTTCTCAC
CCTGATGGATTGCTCTATTTCAACACTTAGGCGCGATTTGAATGAATTGGAGAAAGAAAAGAGTTTAAGGCGGGTCCATG
GTGGAGCCGAACTTACACAGGATTTATCAGAAGAGTTAAGTATTTCTGAAAAAACGTCCAAAAACATTCAAGAAAAAGAA
GAAATCGCGCAAATTGCCTTATCAAAAATTAAAGACGGAGATATTGTCTTTCTAGATGCTGGAACAACAACTGGTCTTTT
AGCAGAACTTATCAATCAATCACATCTTTATCTAACGATTGTAACTAACTCTGTCACGCATTTAGCAAAATTGACAGATG
ACCGATTGATTGTTTATTTACTCGGTGGTCGAGTGAAAAAGGTAACAGATGCAATCATTGGAAGTCAGGCCTTGGAACAA
CTATCTGCCTATCAATTTAATGTGGCCTTTGTGGGTGCGAACGGTTTTGATACCAAGCATGGCGCAATGACGCCAGACCA
TGAAGAAGCAGCAATTAAAGGATTAGCGGTTAAACAAAGTCAGAATGCTTATGTTTTGGCTGACTCTTCCAAATTAGGCC
AAATGAGTTTCGTAAAATTTGCTAATTCTGAAGAGGTTGAATTAATTACCGAGAATAATTAG

Upstream 100 bases:

>100_bases
TTTATTTTTGAACTTTTTTGAAAGAAAATGATAGTTAATGATTGATTTTGAAAGATAAAGGTGTTATAATAAATTTTGTA
AACGAATTCAGGAGATGGAA

Downstream 100 bases:

>100_bases
AGTATGTTTTTTTATGAATAAAAGTGAAAAGATTTCACTAAATGTTAATATTTCAAACTTACGTCTTAAATAAAAGGAGA
ACTATGATTTATACAGTAAC

Product: lactose transport regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MLVNERKKRIVDYLKINRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGGAELTQDLSEELSISEKTSKNIQEKE
EIAQIALSKIKDGDIVFLDAGTTTGLLAELINQSHLYLTIVTNSVTHLAKLTDDRLIVYLLGGRVKKVTDAIIGSQALEQ
LSAYQFNVAFVGANGFDTKHGAMTPDHEEAAIKGLAVKQSQNAYVLADSSKLGQMSFVKFANSEEVELITENN

Sequences:

>Translated_233_residues
MLVNERKKRIVDYLKINRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGGAELTQDLSEELSISEKTSKNIQEKE
EIAQIALSKIKDGDIVFLDAGTTTGLLAELINQSHLYLTIVTNSVTHLAKLTDDRLIVYLLGGRVKKVTDAIIGSQALEQ
LSAYQFNVAFVGANGFDTKHGAMTPDHEEAAIKGLAVKQSQNAYVLADSSKLGQMSFVKFANSEEVELITENN
>Mature_233_residues
MLVNERKKRIVDYLKINRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGGAELTQDLSEELSISEKTSKNIQEKE
EIAQIALSKIKDGDIVFLDAGTTTGLLAELINQSHLYLTIVTNSVTHLAKLTDDRLIVYLLGGRVKKVTDAIIGSQALEQ
LSAYQFNVAFVGANGFDTKHGAMTPDHEEAAIKGLAVKQSQNAYVLADSSKLGQMSFVKFANSEEVELITENN

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=235, Percent_Identity=31.063829787234, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789829, Length=228, Percent_Identity=29.3859649122807, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=27.9475982532751, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=28.3898305084746, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787540, Length=214, Percent_Identity=29.4392523364486, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=28.695652173913, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082344, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=212, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787063, Length=229, Percent_Identity=23.5807860262009, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790635, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 25851; Mature: 25851

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNERKKRIVDYLKINRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGGAELTQ
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DLSEELSISEKTSKNIQEKEEIAQIALSKIKDGDIVFLDAGTTTGLLAELINQSHLYLTI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEE
VTNSVTHLAKLTDDRLIVYLLGGRVKKVTDAIIGSQALEQLSAYQFNVAFVGANGFDTKH
ECCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
GAMTPDHEEAAIKGLAVKQSQNAYVLADSSKLGQMSFVKFANSEEVELITENN
CCCCCCHHHHHHHHEEEECCCCEEEEECCCCCCCCHHEEECCCCCEEEEECCC
>Mature Secondary Structure
MLVNERKKRIVDYLKINRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGGAELTQ
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DLSEELSISEKTSKNIQEKEEIAQIALSKIKDGDIVFLDAGTTTGLLAELINQSHLYLTI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEE
VTNSVTHLAKLTDDRLIVYLLGGRVKKVTDAIIGSQALEQLSAYQFNVAFVGANGFDTKH
ECCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
GAMTPDHEEAAIKGLAVKQSQNAYVLADSSKLGQMSFVKFANSEEVELITENN
CCCCCCHHHHHHHHEEEECCCCEEEEECCCCCCCCHHEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]