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The map label for this gene is fruA [H]

Identifier: 125624370

GI number: 125624370

Start: 1540757

End: 1542661

Strand: Reverse

Name: fruA [H]

Synonym: llmg_1568

Alternate gene names: 125624370

Gene position: 1542661-1540757 (Counterclockwise)

Preceding gene: 125624371

Following gene: 125624366

Centisome position: 60.99

GC content: 40.89

Gene sequence:

>1905_bases
ATGGAAATTAAAGATTTATTAAAAACAGAGGTTATGATTCTTGACCTCCAAGCAACTAGCAAAGAAGCCGTTATTGATGA
AATGGTCAATAAATTAGTTTCTGAAGGTTATGTCAGTGATTTTGCAACTTTTAAAGCAGGAATTATGGCACGTGAAGCGC
AAACTTCAACTGGACTTGGTGACGGGATTGCCATGCCTCACAGTAAAAATACCGCTGTTAATGAACCGGTTGTTCTATTT
GCAAAATCAAAAACTGGTGTTGATTACACGGCATTAGATGGTCAACCTGTCAATCTTTTCTTCATGATTGCAGCACCAGA
TGGTGCTAATGATACTCACTTAGAAGCTTTGGCACAACTTTCCACTTATCTTCTTAAAGACGGTTTCCAAGACCGTTTGC
GAAAAGTTGAATACCCACGCGAAGTCATTCAACTCTTTTCTGAAAAACAAGAAGAAGTTGCAACTCTTGAAAATGCTGAA
CATTACATTGTAGCTGTAACAGCATGTACAACAGGAATTGCCCATACTTACATGGCTGAAGAAGCACTTAAAAAACAAGC
CTTGGAAATGGGTGTTGGTATAAAGGTTGAAACCAATGGTGCGCGTGGAATTGATAATAAATTAACTTCAGCTGATATTC
AAAAAGCTGATGCTGTTATCGTAGCTGCGGACAAAAAAGTCGAAATGAATCGTTTTGCTGGTAAAGAAATGGTTCAAGTT
CCAGTTGCACACGCCATTCGAGATACGGAAGAATTAATTAATCGTGCGCTCTCAGGAAATGCACCAATCTATGAAGCAGA
TGGAACGGATGAAGTAAAAGAAGAATCATCTGGTGGCTTAGGTAAAGCTTTCTATAAACACTTAATGGGTGGTGTTTCTG
CAATGCTTCCATTCGTTGTCGGAGGTGGGATTCTTATCGCTCTTGCTTTCTTGATTGACCAAGCGATGGGGGTTCCTCAA
AGTCAATTGGCCAACCTTGGAGTTTATCATCCTTTAGCTGCTTACTTTAAAAATGTTGGGGGCGCGGCTTTTGCCTTTAT
GTTACCTGTTTTAGCCGGTTTCATTGCAAACTCAATCGCTGATAAGCCTGGTTTAGTTGCTGGTTTTGTCGCTGGTTCTA
TGGCATCTTCTGGTTTGGCTTTTGGTCATTTAGACCCTGCTAAAATGATTCCGTCTGGTTTCTTAGGAGCCTTGGTTGGT
GGTTTCCTTGCTGGTGGAGTGATTATTCTTCTTCGTAAAGTCTTCGCAAAACTTCCGCGTTCACTTGATGGGATTAAAGC
TATCTTGATTTATCCATTAGTTGGAACATTTATCACAGGTTTCCTAATGCTCTTTGTCAATATCCCAATGGCCGCAATTA
ATACTGGACTTTCTAACTTCCTAGCAAGCTTATCAGGCGCATCTGCCCTTGTTCTTGGTTTAGTTGTTGGTGGAATGATG
GCTATTGACCTTGGCGGTCCAATCAACAAAGCTGCTTATATCTTTGCAACTGGTACTTTAGCAGCAACAGTTTCAACTGG
TGGTTCAGTAACAATGGCAGCAGTTATGGCTGGTGGGATGGTTCCACCACTCGCAACTACAGTAGCTGTTATCTTGTTTA
AAAATAAATTTACCAAAGAAGAACGTAATGCTGGTTTGACAAACATTGTGATGGGGCTTTCATTCATCACTGAAGGGTCA
ATTCCATTTGGCGCAGCCGACCCAGCACGCGCAATTCCATCATTTATGATTGGAGCAGCAGTAGCCGGTGGTTTGACTGG
TATGGCCAATATTAAATTGATGGCACCACATGGTGGAGTCTTCGTACTTGCTTTGACTAATAACCCGTTACTTTATCTCT
TGTTCATCTTGATTGGAGCAATTGTTTCAGGCCTATTATTTGGAGCTTTGAAAAAAGCTAAATAA

Upstream 100 bases:

>100_bases
CGATTGCTTGTGGAACTTCAAAGGCATTCTCAGATGATATGCCAAGCCGAGCATTTTTGGAAGATATTTATAAAAAAGTT
AATATTTCAGAGGTGAAATG

Downstream 100 bases:

>100_bases
AATTTAATAAAATGAAAGAAGCGGATAATGATGTGAACCCCAAAAGCTAGACTTTTTAGACAAGAATAATTTCTTGTCTT
TTTTTTGTTATTTTGAATAA

Product: PTS system, fructose specific IIBC components

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEIKDLLKTEVMILDLQATSKEAVIDEMVNKLVSEGYVSDFATFKAGIMAREAQTSTGLGDGIAMPHSKNTAVNEPVVLF
AKSKTGVDYTALDGQPVNLFFMIAAPDGANDTHLEALAQLSTYLLKDGFQDRLRKVEYPREVIQLFSEKQEEVATLENAE
HYIVAVTACTTGIAHTYMAEEALKKQALEMGVGIKVETNGARGIDNKLTSADIQKADAVIVAADKKVEMNRFAGKEMVQV
PVAHAIRDTEELINRALSGNAPIYEADGTDEVKEESSGGLGKAFYKHLMGGVSAMLPFVVGGGILIALAFLIDQAMGVPQ
SQLANLGVYHPLAAYFKNVGGAAFAFMLPVLAGFIANSIADKPGLVAGFVAGSMASSGLAFGHLDPAKMIPSGFLGALVG
GFLAGGVIILLRKVFAKLPRSLDGIKAILIYPLVGTFITGFLMLFVNIPMAAINTGLSNFLASLSGASALVLGLVVGGMM
AIDLGGPINKAAYIFATGTLAATVSTGGSVTMAAVMAGGMVPPLATTVAVILFKNKFTKEERNAGLTNIVMGLSFITEGS
IPFGAADPARAIPSFMIGAAVAGGLTGMANIKLMAPHGGVFVLALTNNPLLYLLFILIGAIVSGLLFGALKKAK

Sequences:

>Translated_634_residues
MEIKDLLKTEVMILDLQATSKEAVIDEMVNKLVSEGYVSDFATFKAGIMAREAQTSTGLGDGIAMPHSKNTAVNEPVVLF
AKSKTGVDYTALDGQPVNLFFMIAAPDGANDTHLEALAQLSTYLLKDGFQDRLRKVEYPREVIQLFSEKQEEVATLENAE
HYIVAVTACTTGIAHTYMAEEALKKQALEMGVGIKVETNGARGIDNKLTSADIQKADAVIVAADKKVEMNRFAGKEMVQV
PVAHAIRDTEELINRALSGNAPIYEADGTDEVKEESSGGLGKAFYKHLMGGVSAMLPFVVGGGILIALAFLIDQAMGVPQ
SQLANLGVYHPLAAYFKNVGGAAFAFMLPVLAGFIANSIADKPGLVAGFVAGSMASSGLAFGHLDPAKMIPSGFLGALVG
GFLAGGVIILLRKVFAKLPRSLDGIKAILIYPLVGTFITGFLMLFVNIPMAAINTGLSNFLASLSGASALVLGLVVGGMM
AIDLGGPINKAAYIFATGTLAATVSTGGSVTMAAVMAGGMVPPLATTVAVILFKNKFTKEERNAGLTNIVMGLSFITEGS
IPFGAADPARAIPSFMIGAAVAGGLTGMANIKLMAPHGGVFVLALTNNPLLYLLFILIGAIVSGLLFGALKKAK
>Mature_634_residues
MEIKDLLKTEVMILDLQATSKEAVIDEMVNKLVSEGYVSDFATFKAGIMAREAQTSTGLGDGIAMPHSKNTAVNEPVVLF
AKSKTGVDYTALDGQPVNLFFMIAAPDGANDTHLEALAQLSTYLLKDGFQDRLRKVEYPREVIQLFSEKQEEVATLENAE
HYIVAVTACTTGIAHTYMAEEALKKQALEMGVGIKVETNGARGIDNKLTSADIQKADAVIVAADKKVEMNRFAGKEMVQV
PVAHAIRDTEELINRALSGNAPIYEADGTDEVKEESSGGLGKAFYKHLMGGVSAMLPFVVGGGILIALAFLIDQAMGVPQ
SQLANLGVYHPLAAYFKNVGGAAFAFMLPVLAGFIANSIADKPGLVAGFVAGSMASSGLAFGHLDPAKMIPSGFLGALVG
GFLAGGVIILLRKVFAKLPRSLDGIKAILIYPLVGTFITGFLMLFVNIPMAAINTGLSNFLASLSGASALVLGLVVGGMM
AIDLGGPINKAAYIFATGTLAATVSTGGSVTMAAVMAGGMVPPLATTVAVILFKNKFTKEERNAGLTNIVMGLSFITEGS
IPFGAADPARAIPSFMIGAAVAGGLTGMANIKLMAPHGGVFVLALTNNPLLYLLFILIGAIVSGLLFGALKKAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=482, Percent_Identity=42.7385892116183, Blast_Score=341, Evalue=7e-95,
Organism=Escherichia coli, GI1786951, Length=616, Percent_Identity=36.2012987012987, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI87082348, Length=444, Percent_Identity=34.2342342342342, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1790386, Length=329, Percent_Identity=35.258358662614, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788729, Length=370, Percent_Identity=29.1891891891892, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=43.6170212765958, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367327, Length=129, Percent_Identity=26.3565891472868, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790390, Length=94, Percent_Identity=38.2978723404255, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788730, Length=87, Percent_Identity=39.0804597701149, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789597, Length=151, Percent_Identity=26.4900662251656, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66129; Mature: 66129

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00583 PFKB_KINASES_1 ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKDLLKTEVMILDLQATSKEAVIDEMVNKLVSEGYVSDFATFKAGIMAREAQTSTGLG
CCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
DGIAMPHSKNTAVNEPVVLFAKSKTGVDYTALDGQPVNLFFMIAAPDGANDTHLEALAQL
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHH
STYLLKDGFQDRLRKVEYPREVIQLFSEKQEEVATLENAEHYIVAVTACTTGIAHTYMAE
HHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
EALKKQALEMGVGIKVETNGARGIDNKLTSADIQKADAVIVAADKKVEMNRFAGKEMVQV
HHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHCCEEEEEECCCCHHHHHCCHHHHHH
PVAHAIRDTEELINRALSGNAPIYEADGTDEVKEESSGGLGKAFYKHLMGGVSAMLPFVV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GGGILIALAFLIDQAMGVPQSQLANLGVYHPLAAYFKNVGGAAFAFMLPVLAGFIANSIA
CCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
DKPGLVAGFVAGSMASSGLAFGHLDPAKMIPSGFLGALVGGFLAGGVIILLRKVFAKLPR
CCCCHHHHHHHHHHHHCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLDGIKAILIYPLVGTFITGFLMLFVNIPMAAINTGLSNFLASLSGASALVLGLVVGGMM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
AIDLGGPINKAAYIFATGTLAATVSTGGSVTMAAVMAGGMVPPLATTVAVILFKNKFTKE
EEECCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHH
ERNAGLTNIVMGLSFITEGSIPFGAADPARAIPSFMIGAAVAGGLTGMANIKLMAPHGGV
HHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
FVLALTNNPLLYLLFILIGAIVSGLLFGALKKAK
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIKDLLKTEVMILDLQATSKEAVIDEMVNKLVSEGYVSDFATFKAGIMAREAQTSTGLG
CCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
DGIAMPHSKNTAVNEPVVLFAKSKTGVDYTALDGQPVNLFFMIAAPDGANDTHLEALAQL
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHH
STYLLKDGFQDRLRKVEYPREVIQLFSEKQEEVATLENAEHYIVAVTACTTGIAHTYMAE
HHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
EALKKQALEMGVGIKVETNGARGIDNKLTSADIQKADAVIVAADKKVEMNRFAGKEMVQV
HHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHCCEEEEEECCCCHHHHHCCHHHHHH
PVAHAIRDTEELINRALSGNAPIYEADGTDEVKEESSGGLGKAFYKHLMGGVSAMLPFVV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GGGILIALAFLIDQAMGVPQSQLANLGVYHPLAAYFKNVGGAAFAFMLPVLAGFIANSIA
CCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
DKPGLVAGFVAGSMASSGLAFGHLDPAKMIPSGFLGALVGGFLAGGVIILLRKVFAKLPR
CCCCHHHHHHHHHHHHCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLDGIKAILIYPLVGTFITGFLMLFVNIPMAAINTGLSNFLASLSGASALVLGLVVGGMM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
AIDLGGPINKAAYIFATGTLAATVSTGGSVTMAAVMAGGMVPPLATTVAVILFKNKFTKE
EEECCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHH
ERNAGLTNIVMGLSFITEGSIPFGAADPARAIPSFMIGAAVAGGLTGMANIKLMAPHGGV
HHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
FVLALTNNPLLYLLFILIGAIVSGLLFGALKKAK
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]