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The map label for this gene is dnaQ [H]

Identifier: 125624340

GI number: 125624340

Start: 1509135

End: 1509968

Strand: Reverse

Name: dnaQ [H]

Synonym: llmg_1537

Alternate gene names: 125624340

Gene position: 1509968-1509135 (Counterclockwise)

Preceding gene: 125624341

Following gene: 125624339

Centisome position: 59.69

GC content: 33.33

Gene sequence:

>834_bases
ATGTCTGAGAAATATGTCGTATTTGACTTTGAAACCACAGGATTTTCTGCACAAAAAAATGAAATTATTCAAATTGGTGC
GGTAAAATATGATGAAAATAATCAAGAACTTGCTAGATTCAATCAATTAGTAAAAAACCAACGTTCTTATGTTTCGACAG
AAATTACCCAATTGACTGGTATAAAACCAGCGGATTTATTGAATCAACCAACGATTGAAGAAATTTTACCCGATTTTTTA
GATTTTATCAAAGGTCATTTAGTAGTGGCACATAATGCACCTTTTGATATTTCATTCCTCTATCAAGCGATTATTGATTG
CGCCATCACCGATGTTGAAGCTTTTCGTGTTTATGATACTTTAGCAGAAAGTAAAAAACTTCTGACCATGTCCTCTTATG
CTTTGGAAAATTTCAAAGATTTACTGGAAATGAATGATTTACGTTCGCACGATGCCCTTAATGACTGTCTAATTACAGCT
AAACTCTATCAATATTTACAAAAAATTGAAGAAGTTGAACGGTCAGTAGAATCAGAAGTTGCTGACGAACTTGGTCAGTT
AGATTTATTTGGTGACAGTTCTGATGAAATTACTGACAGCATTCGTCGAAAGTTAAACTTACCCATTACCAAGGCTTTGG
TCTACTATCAGCAAAATTTGGAACGAAAATGGGAACGGTTTGAAGTTCTAGGAATTTCGGTTGAACGAGAATATTCTACA
GGTTCAAGTCTAAAAATTCGTTTACATAATTCAGAAAAAGTGAAAATTCATTCTGATTTTCTAAAAGAAATGCAAAAAGC
CAATTTCGTCACGATTATGGAGGAAGAGAAATGA

Upstream 100 bases:

>100_bases
GCTGACAGAAAGTTAAAAAACTACCAGAAAACGCTGACAGAAATTCCTGAATTTGGGAAAGTAATTAAAACAAAAGAAAT
TATTGAGGAACTAAATAAAA

Downstream 100 bases:

>100_bases
CAGCAATTTGGAAATTAAAAAAATTTAATCAATTAACAACAGATGAGATGTATCAACTTTTGAGTTTGCGTACGGCTGTC
TTTGTTGTGGAGCAAAATTG

Product: DNA polymerase III, epsilon chain

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQELARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPDFL
DFIKGHLVVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITA
KLYQYLQKIEEVERSVESEVADELGQLDLFGDSSDEITDSIRRKLNLPITKALVYYQQNLERKWERFEVLGISVEREYST
GSSLKIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK

Sequences:

>Translated_277_residues
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQELARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPDFL
DFIKGHLVVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITA
KLYQYLQKIEEVERSVESEVADELGQLDLFGDSSDEITDSIRRKLNLPITKALVYYQQNLERKWERFEVLGISVEREYST
GSSLKIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
>Mature_276_residues
SEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQELARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPDFLD
FIKGHLVVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAK
LYQYLQKIEEVERSVESEVADELGQLDLFGDSSDEITDSIRRKLNLPITKALVYYQQNLERKWERFEVLGISVEREYSTG
SSLKIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=170, Percent_Identity=31.1764705882353, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 32018; Mature: 31886

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQELARFNQLVKNQRSYVSTEITQLTG
CCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IKPADLLNQPTIEEILPDFLDFIKGHLVVAHNAPFDISFLYQAIIDCAITDVEAFRVYDT
CCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAKLYQYLQKIEEVERSVESEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADELGQLDLFGDSSDEITDSIRRKLNLPITKALVYYQQNLERKWERFEVLGISVEREYST
HHHHCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
GSSLKIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
CCEEEEEEECCCEEEEHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure 
SEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQELARFNQLVKNQRSYVSTEITQLTG
CCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IKPADLLNQPTIEEILPDFLDFIKGHLVVAHNAPFDISFLYQAIIDCAITDVEAFRVYDT
CCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAKLYQYLQKIEEVERSVESEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADELGQLDLFGDSSDEITDSIRRKLNLPITKALVYYQQNLERKWERFEVLGISVEREYST
HHHHCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
GSSLKIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
CCEEEEEEECCCEEEEHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]