Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 125624336

GI number: 125624336

Start: 1503379

End: 1504467

Strand: Reverse

Name: ribD [H]

Synonym: llmg_1532

Alternate gene names: 125624336

Gene position: 1504467-1503379 (Counterclockwise)

Preceding gene: 125624338

Following gene: 125624335

Centisome position: 59.48

GC content: 37.1

Gene sequence:

>1089_bases
ATGGAAAATGATGAGCATTTTATGAATTTAGCAATCCTACTGGCTCGAAAAGGAGGGGGAAACGTTAATCCAAATCCTCA
AGTAGGAGCGATTATTGTCAATGATGGTCGAATTATTGGTCAAGGTTATCATGAGAAATATGGAGAAGCACATGCGGAAA
TCAATGCATTTAAATCTTGTATAGAATCACCGGAGGGGTCAACCATTTATGTGACCTTAGAACCTTGTGCCCACCAAGGC
AAGCAACCGCCTTGTTTTGAAGCAATCATCAAAAATAAAGTGAAGCGTGTAGTCATTGGGAGTCTAGACCCAAATCCTTT
AGTAGCTGGTAAGGGAATTGAAGCAATGAAAAAAGCTGGAATTGATGTTTCATTAAAAGTTCTAGAAAAAGAGTGCAAAG
ACTTAAATAAGATTTTTTTTCATTACGTCACTCAAAGAACCCCCTACGTCATGATGAAGTATGCGATGACTCTTGATGGA
AAAATTGCGACTTATAAAGGTCAATCCAAATGGATTACAGGTGAAAAAGCAAGACAAAAGGTACATGAAGACCGTTCACG
TTTCATGGCAATCATGATTGGTGTTGAAACACTTCTGAAAGATGACCCACAATTAACTGCCAGAATAAAAAATGGGATAA
ATCCAATTAGAATTATTTGTGATACTCAACTTCGAACCCCTCTTACGTCTAAGATTGTTTCTACTGCATTTGAAATTCCA
ACAATCATTGCTACCTCAAATGAAAACATTCAAAAACATCAAGCTTTTATTGAAGCCGGTTGCGAGATTTTACTAGTTTC
TTCCATATCTAAACATTTGGATTTGAAAGATTTAATCACTAAGTTAGGAGAAAGAGAAATTGATAGTCTTATTTTAGAAG
GGGGAGCAAGACTCAACGCCTCAGCATTAAAAGCAGGAATTGTTCAAAAAGTTCAAGCCTATATTGCCCCTAAAATATTT
GGTGGGAAAGAAGCTCCAAGTTCTGTTGAAGGTCTAGGAGTAGAGCATCCCGATCAAGCCTATTTACTAGACCGACCTCA
AGTGGCCTATTTAGGAGAAGATATATTATTAGAAAGTGAGCTCATTTAA

Upstream 100 bases:

>100_bases
GGTTTTTTTGAGCTGTTTTTTTGCTTGAATAAAATAGAAAATTATCCTAAGCCCTTGAAATATTATTTTGGGGCTTATTT
TTTTTAGAAAGGATAAATGG

Downstream 100 bases:

>100_bases
TGTTTACAGGAATTATTGAGGAAATAGGAGAGGTAACTCAAATTCAAAAGAGAGATAAGTCGTCTAAATTAATCATTCGA
GCTTCCAGCATCTTAGAAGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MENDEHFMNLAILLARKGGGNVNPNPQVGAIIVNDGRIIGQGYHEKYGEAHAEINAFKSCIESPEGSTIYVTLEPCAHQG
KQPPCFEAIIKNKVKRVVIGSLDPNPLVAGKGIEAMKKAGIDVSLKVLEKECKDLNKIFFHYVTQRTPYVMMKYAMTLDG
KIATYKGQSKWITGEKARQKVHEDRSRFMAIMIGVETLLKDDPQLTARIKNGINPIRIICDTQLRTPLTSKIVSTAFEIP
TIIATSNENIQKHQAFIEAGCEILLVSSISKHLDLKDLITKLGEREIDSLILEGGARLNASALKAGIVQKVQAYIAPKIF
GGKEAPSSVEGLGVEHPDQAYLLDRPQVAYLGEDILLESELI

Sequences:

>Translated_362_residues
MENDEHFMNLAILLARKGGGNVNPNPQVGAIIVNDGRIIGQGYHEKYGEAHAEINAFKSCIESPEGSTIYVTLEPCAHQG
KQPPCFEAIIKNKVKRVVIGSLDPNPLVAGKGIEAMKKAGIDVSLKVLEKECKDLNKIFFHYVTQRTPYVMMKYAMTLDG
KIATYKGQSKWITGEKARQKVHEDRSRFMAIMIGVETLLKDDPQLTARIKNGINPIRIICDTQLRTPLTSKIVSTAFEIP
TIIATSNENIQKHQAFIEAGCEILLVSSISKHLDLKDLITKLGEREIDSLILEGGARLNASALKAGIVQKVQAYIAPKIF
GGKEAPSSVEGLGVEHPDQAYLLDRPQVAYLGEDILLESELI
>Mature_362_residues
MENDEHFMNLAILLARKGGGNVNPNPQVGAIIVNDGRIIGQGYHEKYGEAHAEINAFKSCIESPEGSTIYVTLEPCAHQG
KQPPCFEAIIKNKVKRVVIGSLDPNPLVAGKGIEAMKKAGIDVSLKVLEKECKDLNKIFFHYVTQRTPYVMMKYAMTLDG
KIATYKGQSKWITGEKARQKVHEDRSRFMAIMIGVETLLKDDPQLTARIKNGINPIRIICDTQLRTPLTSKIVSTAFEIP
TIIATSNENIQKHQAFIEAGCEILLVSSISKHLDLKDLITKLGEREIDSLILEGGARLNASALKAGIVQKVQAYIAPKIF
GGKEAPSSVEGLGVEHPDQAYLLDRPQVAYLGEDILLESELI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=373, Percent_Identity=38.0697050938338, Blast_Score=250, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39826; Mature: 39826

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENDEHFMNLAILLARKGGGNVNPNPQVGAIIVNDGRIIGQGYHEKYGEAHAEINAFKSC
CCCCHHHHEEEEEEEECCCCCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHH
IESPEGSTIYVTLEPCAHQGKQPPCFEAIIKNKVKRVVIGSLDPNPLVAGKGIEAMKKAG
HCCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCEEECCCHHHHHHCC
IDVSLKVLEKECKDLNKIFFHYVTQRTPYVMMKYAMTLDGKIATYKGQSKWITGEKARQK
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHEECCEEEEECCCCCEECCHHHHHH
VHEDRSRFMAIMIGVETLLKDDPQLTARIKNGINPIRIICDTQLRTPLTSKIVSTAFEIP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
TIIATSNENIQKHQAFIEAGCEILLVSSISKHLDLKDLITKLGEREIDSLILEGGARLNA
EEEEECCCCHHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCCCCH
SALKAGIVQKVQAYIAPKIFGGKEAPSSVEGLGVEHPDQAYLLDRPQVAYLGEDILLESE
HHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCHHHCCCC
LI
CC
>Mature Secondary Structure
MENDEHFMNLAILLARKGGGNVNPNPQVGAIIVNDGRIIGQGYHEKYGEAHAEINAFKSC
CCCCHHHHEEEEEEEECCCCCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHH
IESPEGSTIYVTLEPCAHQGKQPPCFEAIIKNKVKRVVIGSLDPNPLVAGKGIEAMKKAG
HCCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCEEECCCHHHHHHCC
IDVSLKVLEKECKDLNKIFFHYVTQRTPYVMMKYAMTLDGKIATYKGQSKWITGEKARQK
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHEECCEEEEECCCCCEECCHHHHHH
VHEDRSRFMAIMIGVETLLKDDPQLTARIKNGINPIRIICDTQLRTPLTSKIVSTAFEIP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
TIIATSNENIQKHQAFIEAGCEILLVSSISKHLDLKDLITKLGEREIDSLILEGGARLNA
EEEEECCCCHHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCCCCH
SALKAGIVQKVQAYIAPKIFGGKEAPSSVEGLGVEHPDQAYLLDRPQVAYLGEDILLESE
HHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCHHHCCCC
LI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]