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The map label for this gene is lspA [H]

Identifier: 125624329

GI number: 125624329

Start: 1498812

End: 1499264

Strand: Reverse

Name: lspA [H]

Synonym: llmg_1525

Alternate gene names: 125624329

Gene position: 1499264-1498812 (Counterclockwise)

Preceding gene: 125624330

Following gene: 125624328

Centisome position: 59.27

GC content: 33.11

Gene sequence:

>453_bases
ATGAAAAAATTACTGTCACTTGTAATTATCGTTGTTGGAATTATTGCTGACCAAGTTTTCAAAAATTGGGTTGTTGCTAA
TATTCAACTTGGAGATACAAAAAAAATTTGGCCAGATGTATTGAGCCTGACTTATATTAAAAATGATGGGGCTGCTTGGT
CATCATTTTCTGGTCAACAATGGTTTTTCCTTGTTTTGACACCTATTGTACTCATTGTTGCACTATGGTTTTTGTGGAAA
AAAATGGGACAAAATTGGTATTTTGCTGGCTTAACTTTGATTATTGCGGGAGCTTTAGGGAATTTTATTGACCGCGTTCG
TCAAGGTTTTGTTGTCGATATGTTTCAAACAGAATTTATGGATTTTCCAATCTTTAATATCGCAGATATCTTACTATCTG
TCGGTTTTGTTGTTCTATTTATTGCAATTTTGACGGACAAAGAAACAAAATAA

Upstream 100 bases:

>100_bases
ATTGTCTGATTTTTGGGGGCTTTCTATTTCTGAAAAGGGCTAAAAGTCTATTTTATGATACTTATTGACCCTCGTTGACG
CGGTGTGGTATAATTAAAAT

Downstream 100 bases:

>100_bases
GCTTTTTAAAAAACGAGTGACAGTAAGTAGCATTAAAACCTCTATGAAAAAGGAAAAATCGATTGCCTATAATAAAAATT
ACTGAAGAAAATAAAGATTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKKLLSLVIIVVGIIADQVFKNWVVANIQLGDTKKIWPDVLSLTYIKNDGAAWSSFSGQQWFFLVLTPIVLIVALWFLWK
KMGQNWYFAGLTLIIAGALGNFIDRVRQGFVVDMFQTEFMDFPIFNIADILLSVGFVVLFIAILTDKETK

Sequences:

>Translated_150_residues
MKKLLSLVIIVVGIIADQVFKNWVVANIQLGDTKKIWPDVLSLTYIKNDGAAWSSFSGQQWFFLVLTPIVLIVALWFLWK
KMGQNWYFAGLTLIIAGALGNFIDRVRQGFVVDMFQTEFMDFPIFNIADILLSVGFVVLFIAILTDKETK
>Mature_150_residues
MKKLLSLVIIVVGIIADQVFKNWVVANIQLGDTKKIWPDVLSLTYIKNDGAAWSSFSGQQWFFLVLTPIVLIVALWFLWK
KMGQNWYFAGLTLIIAGALGNFIDRVRQGFVVDMFQTEFMDFPIFNIADILLSVGFVVLFIAILTDKETK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=134, Percent_Identity=40.2985074626866, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17053; Mature: 17053

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSLVIIVVGIIADQVFKNWVVANIQLGDTKKIWPDVLSLTYIKNDGAAWSSFSGQQ
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHEECCCCCCCCCCCCCH
WFFLVLTPIVLIVALWFLWKKMGQNWYFAGLTLIIAGALGNFIDRVRQGFVVDMFQTEFM
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
DFPIFNIADILLSVGFVVLFIAILTDKETK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLLSLVIIVVGIIADQVFKNWVVANIQLGDTKKIWPDVLSLTYIKNDGAAWSSFSGQQ
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHEECCCCCCCCCCCCCH
WFFLVLTPIVLIVALWFLWKKMGQNWYFAGLTLIIAGALGNFIDRVRQGFVVDMFQTEFM
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
DFPIFNIADILLSVGFVVLFIAILTDKETK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]