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The map label for this gene is kinE [H]

Identifier: 125624322

GI number: 125624322

Start: 1491825

End: 1493150

Strand: Reverse

Name: kinE [H]

Synonym: llmg_1518

Alternate gene names: 125624322

Gene position: 1493150-1491825 (Counterclockwise)

Preceding gene: 125624323

Following gene: 125624321

Centisome position: 59.03

GC content: 34.39

Gene sequence:

>1326_bases
ATGAAAAAAACAGAATCTAAAACAAGTGCCAATATCATCACAGAAACTTTTGTCCGTATATTTTTGATTTTTACACTCCT
TGTTACGATAATTGTCTCAGGAATTGTTGCTTTTACAAGTTTACAAATTCGAGAGAGTGAGGGGACGTCTCTGATTTCTT
CGGTACAAGAAGCGGCAGAAAATGGTAACGTAAACTGGGATGAATTTAAACTGGATAGTGAAAAAGATGAAAAATCTACT
TTTGTTAGACTAACAAGGGCTTCTGGAGATATTGATGAAAGTCATGGCACATCACATTTTTTAAAGTCACGGCTTTCTTG
GGGCAATTTTAGTCTGTCAAAAGATGTTATCTTTTGGTATAGCTCAGAAACGGCCAAAAATGGGAATAAAGTAGAATTAT
GGTTAAACATAAATATTGTTGTAAAATCAATGATAAGGGCGATATTAGTCATTGTCGCTGTCATGATTATTCTCTTTTTT
ATCGCTCTAATTTTAATTCGAAAGGCCGCAAATACAATTAGCCAGCCTTTGACTGATATGATGTTAGCGACTGATGAAAA
AGAAGTTAAACAATTACCAGTCAGTAAAAATCCAATTGAGGTTCGTCAGCTAAGTCAAAGTTTTAATCGCTTATTAAACA
GATTAAATCAAAAAATTGAGAATGAGCAGCAGTTTGTTTCGGATGCTTCACATGAACTGAGGACGCCCGTTGCTGCAATT
CGTGGACATGTCACTTTATTAAAAAGAAGATGGCATGAGCATCCCGAAATTATTGATGACTCGCTATCTTATATTGATGA
AGAGTCCCTGAGAATGAAAGGGCTCATTGAAAATTTACTGACAATTTCTCGGGGAAATCATTTGGAAGTAAATAAAGAAA
AATTTAACTTGACTGAATTTACTGACAAAGTGGTCAGTGAAATTCAACCTGCTTTGAGCCAAAAAATTACATTTAATGGA
AAAAGCGAGATTTTTGTCAGGGCTGATAAAATGTCACTTTATAAAATCATCATTGTTTTTATTGAAAATGCTGGAAAATA
TTCACCCCAAGATTCAGAAATTAAAGTAAAAATTAGTTCTGAAAATCATCAAGTAGAGCTGCAAGTTGCTGATGAAGGAG
TGGGTATCCCAGAAGAAGAAAAAATTAATATTTTTGAACGATTTTATCGCATTGATAAATCCCGTTCAAGTGAAATTCCT
GGCACAGGTCTTGGGCTTGCGATTGCTAAACAATATGCGCAATTAAACCATGCTGAAGTCTTTGTCACAAACAATACTCC
GAAAGGATCAATTTTTCATCTCCTTATGGAGTCTATAGAAAACTAA

Upstream 100 bases:

>100_bases
GATGATTGCCTTGACTTTATTAGAATATCGAAAATTGAAGGTACAACTTTCAAAGGGGCAATCATATTCATCTCTGAAAA
ATATTAAAATAAACTAACGA

Downstream 100 bases:

>100_bases
ACTTATATTATGAATAAAAAAAATTACTATATTTTGGGTACTTTGACGACCCTCGCCTTTTTAATTTTAACTGTACTTGT
GAAAATATATTACACACACG

Product: sensor kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAENGNVNWDEFKLDSEKDEKST
FVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWYSSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFF
IALILIRKAANTISQPLTDMMLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAI
RGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEFTDKVVSEIQPALSQKITFNG
KSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISSENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIP
GTGLGLAIAKQYAQLNHAEVFVTNNTPKGSIFHLLMESIEN

Sequences:

>Translated_441_residues
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAENGNVNWDEFKLDSEKDEKST
FVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWYSSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFF
IALILIRKAANTISQPLTDMMLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAI
RGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEFTDKVVSEIQPALSQKITFNG
KSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISSENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIP
GTGLGLAIAKQYAQLNHAEVFVTNNTPKGSIFHLLMESIEN
>Mature_441_residues
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAENGNVNWDEFKLDSEKDEKST
FVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWYSSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFF
IALILIRKAANTISQPLTDMMLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAI
RGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEFTDKVVSEIQPALSQKITFNG
KSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISSENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIP
GTGLGLAIAKQYAQLNHAEVFVTNNTPKGSIFHLLMESIEN

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=316, Percent_Identity=25.3164556962025, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786783, Length=417, Percent_Identity=24.9400479616307, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=29.4354838709677, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=29.5918367346939, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789403, Length=289, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=29.368029739777, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=25.0980392156863, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=30.9803921568627, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=210, Percent_Identity=27.1428571428571, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=25.4125412541254, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=23.6286919831224, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=317, Percent_Identity=25.5520504731861, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=27.1493212669683, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=28.0542986425339, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=25.1028806584362, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787374, Length=223, Percent_Identity=25.1121076233184, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=26.0162601626016, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50029; Mature: 50029

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
NGNVNWDEFKLDSEKDEKSTFVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWY
CCCCCHHHEECCCCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEE
SSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFFIALILIRKAANTISQPLTDM
ECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAI
HHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEF
HHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHH
TDKVVSEIQPALSQKITFNGKSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISS
HHHHHHHHHHHHHCCEEECCCCEEEEEECHHHHHHHHHHHEECCCCCCCCCCEEEEEEEC
ENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIPGTGLGLAIAKQYAQLNHAEV
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
FVTNNTPKGSIFHLLMESIEN
EEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
NGNVNWDEFKLDSEKDEKSTFVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWY
CCCCCHHHEECCCCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEE
SSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFFIALILIRKAANTISQPLTDM
ECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAI
HHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEF
HHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHH
TDKVVSEIQPALSQKITFNGKSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISS
HHHHHHHHHHHHHCCEEECCCCEEEEEECHHHHHHHHHHHEECCCCCCCCCCEEEEEEEC
ENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIPGTGLGLAIAKQYAQLNHAEV
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
FVTNNTPKGSIFHLLMESIEN
EEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]