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The map label for this gene is hexR [C]

Identifier: 125624270

GI number: 125624270

Start: 1435163

End: 1435888

Strand: Reverse

Name: hexR [C]

Synonym: llmg_1462

Alternate gene names: 125624270

Gene position: 1435888-1435163 (Counterclockwise)

Preceding gene: 125624271

Following gene: 125624269

Centisome position: 56.77

GC content: 34.3

Gene sequence:

>726_bases
ATGGCATTTCTAGGTAAGGTGGATTTTAAGAATTTAACAGAAACAGAGAAGGTAATTTATAACTATTTGCGTAATAACTT
TGAGAAGATACCACGTATGCATGTCCGTGATATTGCTTTAGAAGCTCATGCAGGCGCATCAAGTGTGATGCGATTAATTC
ATAAACTGGGTTATCACTCCTATTATCAATTTCAAGAGTTTGTAGAAAAACAACAACTAAAAGCTTCAACAGATAGTGAC
ATCTTTCAGCTTTTGTCGGCGAGCCATTATCCGTCAGAACTGATTGAAAAATGTCGTCAATTGACTGAACAGGTATTAAA
AGCTGATAGTATTATCTTTTTTGGATTAGGTACGTCTGGAAATATCTGTGAATATGCCATGCGAAGATTTGCTACACTAG
GTTTAAATGCTCTATCTTTGACTGATATGACTTATCCCTTAGAATCACATTTGCTAGAATCTCAGGATAGTCTAATCGTT
GTCTTTTCAATTTCTGGTGAGACAGGGGAGTTAATTGAGATTTTACAACACATTAGAAACAGGGAAAAAGTTATGATTAT
TTCTATTACTCCCAAAAAAGAAAGTAGCTTGGCCCAATTAAGTAATTTATCAATCAACTATAAAGTGGAAGAACGAAGAG
TAAATCTTTATGGTGATTTAACCAGCCAAATTCCAGCCATTTTTATCACTGAGGTCCTTTCAGAGATGATTTTTAAAAGT
AAATGA

Upstream 100 bases:

>100_bases
TAAAAATCCTATTGACTATTTTATGTAACATATTGTATAATAACAGAAATATAAAGAAAAGATAATCATCATAATTCTTC
TAAATTAAAAGGAGTGATAA

Downstream 100 bases:

>100_bases
AAATCCGCTTGGAACCAAAAATAAAACTTGAATATTTATCGTAAATAAAAGAGATTCAAAATTGCGCTATATAAGCAATT
GCTGAATATCTTTTTTTACA

Product: putative HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAFLGKVDFKNLTETEKVIYNYLRNNFEKIPRMHVRDIALEAHAGASSVMRLIHKLGYHSYYQFQEFVEKQQLKASTDSD
IFQLLSASHYPSELIEKCRQLTEQVLKADSIIFFGLGTSGNICEYAMRRFATLGLNALSLTDMTYPLESHLLESQDSLIV
VFSISGETGELIEILQHIRNREKVMIISITPKKESSLAQLSNLSINYKVEERRVNLYGDLTSQIPAIFITEVLSEMIFKS
K

Sequences:

>Translated_241_residues
MAFLGKVDFKNLTETEKVIYNYLRNNFEKIPRMHVRDIALEAHAGASSVMRLIHKLGYHSYYQFQEFVEKQQLKASTDSD
IFQLLSASHYPSELIEKCRQLTEQVLKADSIIFFGLGTSGNICEYAMRRFATLGLNALSLTDMTYPLESHLLESQDSLIV
VFSISGETGELIEILQHIRNREKVMIISITPKKESSLAQLSNLSINYKVEERRVNLYGDLTSQIPAIFITEVLSEMIFKS
K
>Mature_240_residues
AFLGKVDFKNLTETEKVIYNYLRNNFEKIPRMHVRDIALEAHAGASSVMRLIHKLGYHSYYQFQEFVEKQQLKASTDSDI
FQLLSASHYPSELIEKCRQLTEQVLKADSIIFFGLGTSGNICEYAMRRFATLGLNALSLTDMTYPLESHLLESQDSLIVV
FSISGETGELIEILQHIRNREKVMIISITPKKESSLAQLSNLSINYKVEERRVNLYGDLTSQIPAIFITEVLSEMIFKSK

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 27568; Mature: 27437

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLGKVDFKNLTETEKVIYNYLRNNFEKIPRMHVRDIALEAHAGASSVMRLIHKLGYHS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHH
YYQFQEFVEKQQLKASTDSDIFQLLSASHYPSELIEKCRQLTEQVLKADSIIFFGLGTSG
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC
NICEYAMRRFATLGLNALSLTDMTYPLESHLLESQDSLIVVFSISGETGELIEILQHIRN
CHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCC
REKVMIISITPKKESSLAQLSNLSINYKVEERRVNLYGDLTSQIPAIFITEVLSEMIFKS
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
AFLGKVDFKNLTETEKVIYNYLRNNFEKIPRMHVRDIALEAHAGASSVMRLIHKLGYHS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHH
YYQFQEFVEKQQLKASTDSDIFQLLSASHYPSELIEKCRQLTEQVLKADSIIFFGLGTSG
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC
NICEYAMRRFATLGLNALSLTDMTYPLESHLLESQDSLIVVFSISGETGELIEILQHIRN
CHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCC
REKVMIISITPKKESSLAQLSNLSINYKVEERRVNLYGDLTSQIPAIFITEVLSEMIFKS
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]